Decompensated Cirrhosis

Also known as: Decompensated cirrhosis of liver (disorder) / Unspecified cirrhosis of liver / Liver Cirrhosis / Cirrhosis of liver / Cirrhosis of liver (disorder) / Cirrhosis liver / Hepatic cirrhosis NOS / Hepatic cirrhosis

Drug	Drug Name	Drug Description
DB09027	Ledipasvir	A direct-acting antiviral agent used to treat specific hepatitis C virus (HCV) infections in combination with other antiviral agents.
DB12914	Resmetirom	A thyroid hormone receptor-beta agonist used to treat noncirrhotic nonalcoholic steatohepatitis (NASH) with moderate to advanced liver fibrosis in adults.
DB08934	Sofosbuvir	A direct-acting antiviral agent used to treat specific hepatitis C virus (HCV) infections in combination with other antiviral agents.

Drug	Drug Name	Target	Type
DB09027	Ledipasvir	Nonstructural protein 5A	target
DB09027	Ledipasvir	P-glycoprotein 1	transporter
DB09027	Ledipasvir	ATP-binding cassette sub-family G member 2	transporter
DB12914	Resmetirom	Cytochrome P450 2C8	enzyme
DB12914	Resmetirom	UDP-glucuronosyltransferase 1-4	enzyme
DB12914	Resmetirom	UDP-glucuronosyltransferase 1-9	enzyme
DB12914	Resmetirom	Solute carrier organic anion transporter family member 1B1	transporter
DB12914	Resmetirom	Solute carrier organic anion transporter family member 1B3	transporter
DB12914	Resmetirom	ATP-binding cassette sub-family G member 2	transporter
DB12914	Resmetirom	Solute carrier family 22 member 8	transporter
DB12914	Resmetirom	Bile salt export pump	transporter
DB12914	Resmetirom	Thyroid hormone receptor beta	target
DB08934	Sofosbuvir	P-glycoprotein 1	transporter
DB08934	Sofosbuvir	ATP-binding cassette sub-family G member 2	transporter
DB08934	Sofosbuvir	RNA-dependent RNA-polymerase	target
DB08934	Sofosbuvir	Lysosomal protective protein	enzyme
DB08934	Sofosbuvir	Carboxylesterase	enzyme
DB08934	Sofosbuvir	Histidine triad nucleotide-binding protein 1	enzyme
DB08934	Sofosbuvir	UMP-CMP kinase	enzyme
DB08934	Sofosbuvir	Nucleoside diphosphate kinase A	enzyme

Drug	Drug Name	Phase	Status	Count
DB17743	Fecal microbiota	1 / 2	Unknown Status	1
DB05408	Emricasan	2	Unknown Status	1
DB15726	Human Umbilical Cord Mesenchymal Stem Cells	2	Not Yet Recruiting	1
DB15726	Human Umbilical Cord Mesenchymal Stem Cells	2	Recruiting	1
DB01015	Sulfamethoxazole	2	Terminated	1
DB02638	Terlipressin	2	Terminated	1
DB00440	Trimethoprim	2	Terminated	1
DB00129	Ornithine	2 / 3	Completed	1
DB01220	Rifaximin	2 / 3	Terminated	1
DB09183	Dasabuvir	3	Completed	1
DB09027	Ledipasvir	3	Completed	1
DB09296	Ombitasvir	3	Completed	1
DB09297	Paritaprevir	3	Completed	1
DB00811	Ribavirin	3	Completed	1
DB00503	Ritonavir	3	Completed	1
DB08934	Sofosbuvir	3	Completed	1
DB00118	Ademetionine	4	Recruiting	1
DB11995	Avatrombopag	4	Recruiting	1
DB00442	Entecavir	4	Unknown Status	1
DB00143	Glutathione	4	Recruiting	1
DB00062	Albumin human	Not Available	Active Not Recruiting	1
DB00062	Albumin human	Not Available	Completed	2
DB00062	Albumin human	Not Available	Not Yet Recruiting	3
DB00062	Albumin human	Not Available	Unknown Status	1
DB09102	Daclatasvir	Not Available	Completed	1
DB06292	Dapagliflozin	Not Available	Not Yet Recruiting	1
DB05408	Emricasan	Not Available	Terminated	1
DB00016	Erythropoietin	Not Available	Completed	1
DB01175	Escitalopram	Not Available	Completed	1
DB00099	Filgrastim	Not Available	Completed	1
DB00695	Furosemide	Not Available	Completed	1
DB00331	Metformin	Not Available	Not Yet Recruiting	1
DB00211	Midodrine	Not Available	Completed	1
DB00211	Midodrine	Not Available	Not Yet Recruiting	1
DB14375	Milk thistle	Not Available	Completed	1
DB00008	Peginterferon alfa-2a	Not Available	Available	1
DB01022	Phylloquinone	Not Available	Completed	1
DB00571	Propranolol	Not Available	Completed	1
DB00811	Ribavirin	Not Available	Completed	1
DB01220	Rifaximin	Not Available	Recruiting	1
DB09298	Silibinin	Not Available	Completed	1
DB01261	Sitagliptin	Not Available	Not Yet Recruiting	1
DB08934	Sofosbuvir	Not Available	Completed	1
DB00421	Spironolactone	Not Available	Completed	1
DB00300	Tenofovir disoproxil	Not Available	Available	1