Moderate to Severe Alzheimer's Disease

Also known as: Moderate-to-severe Alzheimer's Disease / Moderate to severe Alzheimer’s disease / Moderate to Severe Alzheimer

Drug	Drug Name	Drug Description
DB01043	Memantine	An NMDA receptor antagonist used to treat moderate to severe dementia in Alzheimer's.

Drug	Drug Name	Target	Type
DB01043	Memantine	Cytochrome P450 2B6	enzyme
DB01043	Memantine	Solute carrier family 22 member 2	transporter
DB01043	Memantine	5-hydroxytryptamine receptor 3A	target
DB01043	Memantine	Neuronal acetylcholine receptor subunit alpha-7	target
DB01043	Memantine	Cytochrome P450 2A6	enzyme
DB01043	Memantine	Cytochrome P450 2C19	enzyme
DB01043	Memantine	Dopamine D2 receptor	target
DB01043	Memantine	Glutamate receptor ionotropic, NMDA 1	target
DB01043	Memantine	Sodium/hydrogen exchanger 1	transporter
DB01043	Memantine	Solute carrier family 22 member 4	transporter
DB01043	Memantine	Multidrug and toxin extrusion protein 1	transporter
DB01043	Memantine	Glutamate (NMDA) receptor	target
DB01043	Memantine	GABA(A) Receptor	target
DB01043	Memantine	Glycine receptors	target

Drug	Drug Name	Phase	Status	Count
DB11725	Latrepirdine	3	Terminated	1
DB12747	Tertomotide	3	Not Yet Recruiting	1
DB00843	Donepezil	4	Unknown Status	1
DB01043	Memantine	4	Unknown Status	1