Increased Intra Ocular Pressure (IOP)
Also known as: Elevated IOP / Increased IOP / Increased ocular pressure / Raised Ocular Pressure / Intraocular pressure raised / Increased ocular tension / Elevated Intraocular Pressure / Increase in intraocular pressure (IOP) / Increase in intraocular pressure / Intraocular pressure increased / Increased intraocular pressure / Raised Intraocular Pressure / Elevation in intraocular pressure / Elevation of intraocular pressure / (Ocular hypertension) or (raised intra-ocular pressure - finding or diagnosis) / (Borderline glaucoma) or (ocular hypertension) or (increased intra-ocular pressure) / Raised intraocular pressure (finding) / IOP increased / Raised IOP / Intraocular pressure high / Ocular tension increased / Tension ocular increased / Pressure intraocular increased
| Drug | Drug Name | Drug Description |
|---|---|---|
| DB00195 | Betaxolol | A cardioselective beta blocking agent commonly used to treat hypertension and elevated intraocular pressure (when administered ophthalmically). |
| DB00905 | Bimatoprost | A prostaglandin analog used to treat hypotrichosis of the eyelashes and intraocular pressure in open angle glaucoma or ocular hypertension. |
| DB00484 | Brimonidine | An alpha-2 adrenergic agonist used to treat glaucoma and ocular hypertension, as well as facial erythema in rosacea. |
| DB01194 | Brinzolamide | A carbonic anhydrase inhibitor used for the reduction of elevated intraocular pressure in patients with ocular hypertension or open-angle glaucoma. |
| DB00411 | Carbamoylcholine | A direct acting miotic agent administered ophthalmically to decrease intraocular pressure after cataract surgery, and to induce miosis during surgery. |
| DB00521 | Carteolol | A beta adrenergic antagonist used to treat arrhythmia, angina, hypertension, and glaucoma. |
| DB00869 | Dorzolamide | A carbonic anhydrase inhibitor used to treat high intraocular pressure in ocular hypertension and open angle glaucoma. |
| DB00654 | Latanoprost | An isopropyl ester prodrug used to treat increased intraocular pressure. |
| DB11660 | Latanoprostene bunod | A prostaglandin analog used to reduce ocular hypertension or treat open-angle glaucoma. |
| DB00742 | Mannitol | A sugar alcohol used to test for asthma, to reduce intracranial and intraocular pressure, to measure glomerular filtration rate, and to manage pulmonary symptoms associated with cystic fibrosis. |
| DB13931 | Netarsudil | A rho kinase inhibitor used to reduce intraocular pressure in patients with open angle glaucoma or ocular hypertension. |
| DB15071 | Omidenepag isopropyl | An agonist of the prostaglandin EP2 receptor indicated for the reduction of elevated intraocular pressure. |
| DB01085 | Pilocarpine | A muscarinic cholinergic agonist used on the eye to treat elevated intraocular pressure, various types of glaucoma, and to induce miosis. Also available orally to treat symptoms of dry mouth associated with Sjogren's syndrome and radiotherapy. |
| DB09153 | Sodium chloride | An ingredient found in a variety of nutritional products as a source of electrolytes and water. |
| DB08819 | Tafluprost | An ophthalmic prostaglandin analog used to lower intraocular pressure in patients with ocular hypertension or open-angle glaucoma. |
| DB00373 | Timolol | A non-selective beta adrenergic blocker used in the treatment of elevated intraocular pressure in ocular hypertension or open angle glaucoma. |
| DB00287 | Travoprost | A prostaglandin analog used in the treatment of elevated intraocular pressure due to open angle glaucoma or ocular hypertension. |
| Drug | Drug Name | Phase | Status | Count |
|---|---|---|---|---|
| DB05757 | DNB-001 | 1 / 2 | Completed | 1 |
| DB14875 | AZD-4017 | 2 | Completed | 1 |
| DB00654 | Latanoprost | 2 | Completed | 1 |
| DB00654 | Latanoprost | 3 | Active Not Recruiting | 1 |
| DB00653 | Magnesium sulfate | 3 | Completed | 1 |