Prophylaxis of Venous Thromboembolic Events

Also known as: Prophylaxis, Thromboembolism, Venous / VTE Prophylaxis / Prophylaxis of VTE / Prophylaxis of Venous Thromboembolism / Venous thromboembolism prophylaxis / Anticoagulant prophylaxis / Prescription of prophylactic anticoagulant (procedure) / Thrombosis prophylaxis / Thromboembolism prophylaxis / Anticoagulant prophylaxis (procedure)

Drug	Drug Name	Drug Description
DB12364	Betrixaban	A Factor Xa inhibitor used for prophylaxis of venous thromboembolism in hospitalized patients.
DB06779	Dalteparin	A low molecular weight heparin used for the prophylaxis of thrombotic events in certain patients and prevent acute cardiac ischemic events in patients with unstable angina and non-Q-wave myocardial infarction.
DB08813	Nadroparin	A low molecular weight heparin used for the prophylaxis of thrombotic events and deep vein thrombosis, and prevent unstable angina and non-Q-wave myocardial infarction.
DB06228	Rivaroxaban	A factor Xa inhibitor used to treat deep vein thrombosis (DVT) and pulmonary embolism (PE). May also be used as thrombosis prophylaxis in specific situations.
DB06822	Tinzaparin	A low molecular weight heparin used for the treatment of acute symptomatic deep vein thrombosis with or without pulmonary embolism when administered in conjunction with warfarin.

Drug	Drug Name	Target	Type
DB12364	Betrixaban	ATP-dependent translocase ABCB1	transporter
DB12364	Betrixaban	Coagulation factor X	target
DB12364	Betrixaban	Potassium voltage-gated channel subfamily H member 2	transporter
DB06779	Dalteparin	Vascular endothelial growth factor A, long form	target
DB06779	Dalteparin	Heparanase	enzyme
DB06779	Dalteparin	Antithrombin-III	target
DB06779	Dalteparin	P-selectin	target
DB08813	Nadroparin	Protein c-Fos	target
DB08813	Nadroparin	Myc proto-oncogene protein	target
DB08813	Nadroparin	P-selectin	target
DB08813	Nadroparin	Antithrombin-III	target
DB06228	Rivaroxaban	Coagulation factor X	target
DB06228	Rivaroxaban	Cytochrome P450 3A4	enzyme
DB06228	Rivaroxaban	Cytochrome P450 2J2	enzyme
DB06228	Rivaroxaban	ATP-dependent translocase ABCB1	transporter
DB06228	Rivaroxaban	Cytochrome P450 3A5	enzyme
DB06228	Rivaroxaban	Broad substrate specificity ATP-binding cassette transporter ABCG2	transporter
DB06822	Tinzaparin	Antithrombin-III	target
DB06822	Tinzaparin	A disintegrin and metalloproteinase with thrombospondin motifs 4	enzyme
DB06822	Tinzaparin	Integrin alpha-4	target
DB06822	Tinzaparin	Stromal cell-derived factor 1	target

Drug	Drug Name	Phase	Status	Count
DB12364	Betrixaban	1	Terminated	1
DB06228	Rivaroxaban	1	Completed	2
DB06228	Rivaroxaban	2	Completed	1
DB06050	TB-402	2	Completed	1
DB06228	Rivaroxaban	Not Available	Withdrawn	1