Severe Combined Immunodeficiencies (SCID)

Also known as: Severe Combined Immunodeficiency Disease / SCID / Severe Combined Immunodeficiency Syndrome / Severe Combined Immunodeficiency (SCID) / Severe Combined Immunodeficiency / Severe Combined Immune Deficiency (SCID) / Severe Combined Immune Deficiency / Severe combined immunodeficiency disease (disorder) / Combined immunodeficiency, unspecified / Combined immunodeficiency / Combined immunodeficiency syndrome / Combined immunity deficiency / Combined immunodeficiencies / Combined immunodeficiency disease (disorder)

Drug	Drug Name	Drug Description
DB00061	Pegademase	A modified form of bovine adenosine deaminase used to treat adenosine deaminase deficiency, a condition which leads to the formation of adenosine metabolites which are cytotoxic to lymphocytes.

Drug	Drug Name	Target	Type
DB00061	Pegademase	Adenosine	target
DB00061	Pegademase	Growth factor receptor-bound protein 2	target

Drug	Drug Name	Phase	Status	Count
DB00087	Alemtuzumab	1	Completed	1
DB16367	Autologous peripheral blood-derived CD34+ cells	1	Completed	1
DB00091	Cyclosporine	1	Completed	1
DB00099	Filgrastim	1	Completed	1
DB00688	Mycophenolate mofetil	1	Completed	1
DB18263	TBX-1400	1	Not Yet Recruiting	1
DB00495	Zidovudine	1	Completed	1
DB00087	Alemtuzumab	1 / 2	Terminated	1
DB00098	Antithymocyte immunoglobulin (rabbit)	1 / 2	Active Not Recruiting	1
DB18136	Briquilimab	1 / 2	Recruiting	1
DB01008	Busulfan	1 / 2	Active Not Recruiting	1
DB01008	Busulfan	1 / 2	Completed	2
DB01008	Busulfan	1 / 2	Enrolling by Invitation	1
DB01008	Busulfan	1 / 2	Recruiting	1
DB00099	Filgrastim	1 / 2	Enrolling by Invitation	1
DB01073	Fludarabine	1 / 2	Active Not Recruiting	1
DB01073	Fludarabine	1 / 2	Completed	1
DB01073	Fludarabine	1 / 2	Terminated	1
DB00877	Sirolimus	1 / 2	Enrolling by Invitation	1
DB04572	Thiotepa	1 / 2	Active Not Recruiting	1
DB04572	Thiotepa	1 / 2	Completed	1
DB00087	Alemtuzumab	2	Recruiting	1
DB00087	Alemtuzumab	2	Terminated	1
DB01008	Busulfan	2	Recruiting	1
DB00099	Filgrastim	2	Terminated	1
DB01073	Fludarabine	2	Completed	1
DB01073	Fludarabine	2	Recruiting	1
DB01042	Melphalan	2	Completed	1
DB01042	Melphalan	2	Recruiting	1
DB00563	Methotrexate	2	Completed	1
DB00688	Mycophenolate mofetil	2	Completed	1
DB06809	Plerixafor	2	Terminated	1
DB00877	Sirolimus	2	Withdrawn	1
DB00864	Tacrolimus	2	Completed	1
DB04572	Thiotepa	2	Recruiting	1
DB00531	Cyclophosphamide	2 / 3	Unknown Status	1
DB01073	Fludarabine	2 / 3	Unknown Status	1
DB14712	Elapegademase	3	Completed	1
DB00028	Human immunoglobulin G	3	Completed	1
DB00061	Pegademase	3	Completed	1
DB00640	Adenosine	Not Available	Enrolling by Invitation	1
DB00087	Alemtuzumab	Not Available	Recruiting	1
DB01008	Busulfan	Not Available	Recruiting	1
DB01008	Busulfan	Not Available	Terminated	1
DB09110	Coenzyme M	Not Available	Recruiting	1
DB00531	Cyclophosphamide	Not Available	Recruiting	1
DB00531	Cyclophosphamide	Not Available	Terminated	1
DB00091	Cyclosporine	Not Available	Terminated	1
DB14712	Elapegademase	Not Available	Completed	1
DB00773	Etoposide	Not Available	Terminated	1
DB01073	Fludarabine	Not Available	Recruiting	1
DB01042	Melphalan	Not Available	Recruiting	1
DB00563	Methotrexate	Not Available	Terminated	1
DB00959	Methylprednisolone	Not Available	Terminated	1
DB00635	Prednisone	Not Available	Terminated	1