Advanced Urothelial Carcinoma
Also known as: Advanced transitional cell carcinoma
| Drug | Drug Name | Drug Description |
|---|---|---|
| DB11641 | Vinflunine | A vinca alkaloid used to treat advanced or metastatic transitional cell carcinoma of the urothelial tract after a platinum containing treatment has failed. |
| Drug | Drug Name | Target | Type |
|---|---|---|---|
| DB11641 | Vinflunine | ATP-binding cassette sub-family B member 5 | transporter |
| DB11641 | Vinflunine | P-glycoprotein 1 | transporter |
| DB11641 | Vinflunine | Serum albumin | carrier |
| DB11641 | Vinflunine | alpha1-acid glycoprotein | carrier |
| DB11641 | Vinflunine | Cytochrome P450 3A4 | enzyme |
| DB11641 | Vinflunine | Tubulin beta chain | target |