Polycystic Ovaries Syndrome

Also known as: Polycystic Ovarian Syndrome (PCOS) / Poly Cystic Ovary Syndrome / Polycystic Ovary Syndrome / Polycystic Ovary / Polycystic Ovary Syndrome, PCOS / Polycystic Ovary Syndrome (PCOS) / Polycystic Ovaries / Polycystic Ovarian Syndrome / PCOS / Polycystic ovary (disorder) / Sclerocystic ovary syndrome / Stein-Leventhal syndrome / Multicystic ovaries / (Polycystic ovaries) or (isosexual virilisation) or (Stein-Leventhal syndrome) or (multicystic ovaries) / (Polycystic ovaries) or (Stein-Leventhal syndrome) / Polycystic ovaries (disorder)

DrugDrug NameDrug Description
DB00823Ethynodiol diacetateAn oral contraceptive used to prevent pregnancy.
DB01216FinasterideAn antiandrogenic compound that is used for the treatment of symptomatic benign prostatic hyperplasia (BPH) and male pattern hair loss in adult males by inhibiting Type II 5-alpha reductase.
DB01006LetrozoleAn aromatase inhibitor used to treat breast cancer in postmenopausal women.
DB14741Luteinizing hormoneNot Annotated
DB01357MestranolA synthetic estradiol found in oral contraceptive pills for contraception and the treatment of other conditions in the female reproductive system, such as dysmenorrhea and dysfunctional uterine bleeding.
DB00331MetforminA biguanide drug used in conjunction with diet and exercise for glycemic control in type 2 diabetes mellitus and used off-label for insulin resistance in polycystic ovary syndrome (PCOS).
DB06713NorelgestrominA progestin used for the prevention of pregnancy in women who elect to use a transdermal patch as a method of contraception.
DB00957NorgestimateA progesterone used as a contraceptive and to treat acne vulgaris.
DB09389NorgestrelA progestin used in combination with ethinyl estradiol for oral contraception and prevention of pregnancy in women.
DrugDrug NameTargetType
DB00823Ethynodiol diacetateEstrogen receptor alphatarget
DB00823Ethynodiol diacetateProgesterone receptortarget
DB00823Ethynodiol diacetateCytochrome P450 3A4enzyme
DB01216Finasteride3-oxo-5-alpha-steroid 4-dehydrogenase 1target
DB01216FinasterideCytochrome P450 3A4enzyme
DB01216Finasteride3-oxo-5-alpha-steroid 4-dehydrogenase 2target
DB01216Finasteride3-oxo-5-beta-steroid 4-dehydrogenasetarget
DB01216FinasterideCytochrome P450 3A5enzyme
DB01216FinasterideCytochrome P450 3A7enzyme
DB01216FinasterideSolute carrier family 12 member 5transporter
DB01006LetrozoleCytochrome P450 19A1target
DB01006LetrozoleCytochrome P450 3A4enzyme
DB01006LetrozoleCytochrome P450 2A6enzyme
DB01006LetrozoleCytochrome P450 19A1enzyme
DB01006LetrozoleCytochrome P450 2C19enzyme
DB01006LetrozoleUDP-glucuronosyltransferase 2B7enzyme
DB01006LetrozoleSerum albumincarrier
DB01006LetrozoleP-glycoprotein 1transporter
DB01357MestranolEstrogen receptor alphatarget
DB01357MestranolCytochrome P450 2C9enzyme
DB01357MestranolCytochrome P450 3A4enzyme
DB01357MestranolCytochrome P450 2C8enzyme
DB00331Metformin5'-AMP-activated protein kinase subunit beta-1target
DB00331MetforminSolute carrier family 22 member 2transporter
DB00331MetforminSolute carrier family 22 member 1transporter
DB00331MetforminMultidrug and toxin extrusion protein 1transporter
DB00331MetforminEquilibrative nucleoside transporter 4transporter
DB00331MetforminSolute carrier family 22 member 3transporter
DB00331MetforminMultidrug and toxin extrusion protein 2transporter
DB00331MetforminElectron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrialtarget
DB00331MetforminGlycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmictarget
DB06713NorelgestrominSteryl-sulfataseenzyme
DB06713NorelgestrominProgesterone receptortarget
DB06713NorelgestrominSerum albumintarget
DB06713NorelgestrominAndrogen receptortarget
DB06713NorelgestrominCytochrome P450 3A4enzyme
DB00957NorgestimateProgesterone receptortarget
DB00957NorgestimateEstrogen receptor alphatarget
DB00957NorgestimateCanalicular multispecific organic anion transporter 1transporter
DB00957NorgestimateCytochrome P450 3A4enzyme
DB00957NorgestimateAndrogen receptortarget
DB00957NorgestimateCytochrome P450 2B6enzyme
DB00957NorgestimateCytochrome P450 2C9enzyme
DB00957NorgestimateUDP-glucuronosyltransferase 1-1enzyme
DB00957NorgestimateSerum albumincarrier
DB00957NorgestimateSex hormone-binding globulincarrier
DB00957NorgestimateP-glycoprotein 1transporter
DB09389NorgestrelProgesterone receptortarget
DB09389Norgestrel3-oxo-5-alpha-steroid 4-dehydrogenase 1target
DB09389NorgestrelAndrogen receptortarget
DB09389NorgestrelCytochrome P450 3A4enzyme
DB09389NorgestrelCytochrome P450 19A1enzyme
DrugDrug NamePhaseStatusCount
DB00097Choriogonadotropin alfa0Recruiting1
DB00097Choriogonadotropin alfa0Withdrawn1
DB09126Chorionic Gonadotropin (Human)0Completed1
DB00882Clomifene0Completed1
DB01285Corticotropin0Recruiting1
DB04839Cyproterone acetate0Completed1
DB01234Dexamethasone0Withdrawn1
DB00783Estradiol0Recruiting2
DB00499Flutamide0Recruiting1
DB00158Folic acid0Not Yet Recruiting1
DB06785Ganirelix0Completed1
DB00741Hydrocortisone0Withdrawn2
DB14541Hydrocortisone cypionate0Withdrawn1
DB13178Inositol0Not Yet Recruiting1
DB11196Inositol0Unknown Status1
DB01006Letrozole0Completed2
DB00007Leuprolide0Withdrawn1
DB00331Metformin0Completed5
DB00331Metformin0Not Yet Recruiting1
DB00331Metformin0Recruiting3
DB00331Metformin0Unknown Status1
DB01132Pioglitazone0Completed4
DB00396Progesterone0Recruiting2
DB00421Spironolactone0Completed1
DB00421Spironolactone0Recruiting3
DB00624Testosterone0Completed1
DB01284Tetracosactide0Recruiting1
DB01284Tetracosactide0Withdrawn1
DB00882Clomifene1Unknown Status1
DB01395Drospirenone1Unknown Status1
DB00783Estradiol1Unknown Status1
DB00977Ethinylestradiol1Unknown Status1
DB13961Fish oil1Suspended1
DB00499Flutamide1Active Not Recruiting1
DB00644Gonadorelin1Recruiting1
DB01167Itraconazole1Terminated1
DB01006Letrozole1Not Yet Recruiting1
DB00331Metformin1Completed1
DB00331Metformin1Recruiting1
DB00331Metformin1Suspended1
DB08893Mirabegron1Recruiting1
DB13981Nomegestrol acetate1Unknown Status1
DB11062Octisalate1Withdrawn1
DB09535Octocrylene1Withdrawn1
DB00396Progesterone1Completed1
DB00396Progesterone1Recruiting1
DB01399Salsalate1Terminated1
DB09321Zinc oxide1Withdrawn1
DB08907Canagliflozin1 / 2Enrolling by Invitation1
DB00882Clomifene1 / 2Not Yet Recruiting1
DB00158Folic acid1 / 2Unknown Status1
DB15823Lactobacillus acidophilus1 / 2Recruiting1
DB16540Lactobacillus delbrueckii bulgaricus1 / 2Recruiting1
DB00331Metformin1 / 2Enrolling by Invitation1
DB00331Metformin1 / 2Recruiting1
DB11062Octisalate1 / 2Enrolling by Invitation1
DB09535Octocrylene1 / 2Enrolling by Invitation1
DB01261Sitagliptin1 / 2Recruiting1
DB11094Vitamin D1 / 2Not Yet Recruiting1
DB09321Zinc oxide1 / 2Enrolling by Invitation1
DB08842Acetylcarnitine2Completed1
DB06151Acetylcysteine2Completed1
DB00026Anakinra2Completed1
DB01076Atorvastatin2Completed1
DB00169Cholecalciferol2Recruiting1
DB09126Chorionic Gonadotropin (Human)2Unknown Status1
DB00882Clomifene2Completed1
DB00882Clomifene2Enrolling by Invitation1
DB00882Clomifene2Unknown Status2
DB04839Cyproterone acetate2Completed1
DB04839Cyproterone acetate2Unknown Status1
DB11979Elagolix2Completed1
DB00977Ethinylestradiol2Completed1
DB00977Ethinylestradiol2Unknown Status1
DB01276Exenatide2Completed1
DB00499Flutamide2Recruiting1
DB00066Follitropin2Unknown Status1
DB09024Follitropin2Unknown Status1
DB00644Gonadorelin2Enrolling by Invitation1
DB01050Ibuprofen2Enrolling by Invitation1
DB13178Inositol2Recruiting1
DB13178Inositol2Unknown Status1
DB01006Letrozole2Unknown Status1
DB00007Leuprolide2Completed1
DB00583Levocarnitine2Completed2
DB15048Licogliflozin2Completed1
DB00331Metformin2Completed8
DB00331Metformin2Enrolling by Invitation1
DB00331Metformin2Recruiting1
DB06710Methyltestosterone2Enrolling by Invitation1
DB01083Orlistat2Completed1
DB11692Pavinetant2Terminated1
DB01132Pioglitazone2Completed2
DB02709Resveratrol2Completed1
DB01399Salsalate2Recruiting1
DB00421Spironolactone2Completed1
DB00094Urofollitropin2Unknown Status1
DB11094Vitamin D2Completed1
DB09145Water2Unknown Status1
DB00097Choriogonadotropin alfa2 / 3Completed1
DB00882Clomifene2 / 3Completed1
DB15350D-chiro-Inositol2 / 3Completed1
DB09038Empagliflozin2 / 3Completed1
DB01276Exenatide2 / 3Active Not Recruiting1
DB13178Inositol2 / 3Completed1
DB01006Letrozole2 / 3Completed1
DB00331Metformin2 / 3Completed3
DB00331Metformin2 / 3Unknown Status1
DB00396Progesterone2 / 3Completed1
DB13928Semaglutide2 / 3Recruiting1
DB00421Spironolactone2 / 3Completed1
DB16447Thymoquinone2 / 3Completed1
DB11340Ubiquinol2 / 3Completed1
DB00630Alendronic acid3Completed1
DB13100Biguanide3Completed1
DB01200Bromocriptine3Unknown Status1
DB00050Cetrorelix3Completed3
DB00169Cholecalciferol3Completed1
DB00097Choriogonadotropin alfa3Completed3
DB09126Chorionic Gonadotropin (Human)3Completed3
DB00882Clomifene3Completed4
DB00882Clomifene3Not Yet Recruiting1
DB00882Clomifene3Unknown Status1
DB00882Clomifene3Withdrawn1
DB09066Corifollitropin alfa3Recruiting1
DB06292Dapagliflozin3Completed1
DB06292Dapagliflozin3Recruiting1
DB06699Degarelix3Completed1
DB00304Desogestrel3Recruiting1
DB01234Dexamethasone3Completed1
DB00254Doxycycline3Completed1
DB01395Drospirenone3Completed3
DB01395Drospirenone3Recruiting1
DB00977Ethinylestradiol3Completed3
DB00977Ethinylestradiol3Recruiting1
DB01276Exenatide3Completed1
DB00158Folic acid3Unknown Status1
DB00066Follitropin3Completed1
DB09024Follitropin3Completed1
DB00066Follitropin3Recruiting1
DB00644Gonadorelin3Completed2
DB13178Inositol3Unknown Status1
DB00030Insulin human3Completed1
DB01006Letrozole3Completed3
DB01006Letrozole3Recruiting1
DB06655Liraglutide3Completed1
DB00331Metformin3Completed16
DB00331Metformin3Recruiting1
DB00331Metformin3Unknown Status1
DB00331Metformin3Withdrawn1
DB00191Phentermine3Completed1
DB00481Raloxifene3Completed1
DB06335Saxagliptin3Completed1
DB00641Simvastatin3Completed1
DB00273Topiramate3Completed1
DB06825Triptorelin3Completed1
DB00284Acarbose4Unknown Status1
DB06203Alogliptin4Completed1
DB08907Canagliflozin4Enrolling by Invitation1
DB00050Cetrorelix4Recruiting3
DB00169Cholecalciferol4Completed3
DB00169Cholecalciferol4Terminated1
DB09126Chorionic Gonadotropin (Human)4Recruiting3
DB09126Chorionic Gonadotropin (Human)4Withdrawn1
DB00882Clomifene4Completed10
DB00882Clomifene4Not Yet Recruiting1
DB00882Clomifene4Recruiting4
DB00882Clomifene4Withdrawn2
DB04839Cyproterone acetate4Completed2
DB04839Cyproterone acetate4Recruiting1
DB04839Cyproterone acetate4Unknown Status2
DB00151Cysteine4Completed1
DB01395Drospirenone4Completed4
DB01395Drospirenone4Recruiting1
DB01395Drospirenone4Unknown Status1
DB09045Dulaglutide4Enrolling by Invitation1
DB01175Escitalopram4Completed1
DB00783Estradiol4Terminated1
DB13956Estradiol valerate4Completed1
DB13956Estradiol valerate4Withdrawn1
DB00977Ethinylestradiol4Completed6
DB00977Ethinylestradiol4Recruiting3
DB00977Ethinylestradiol4Unknown Status2
DB00294Etonogestrel4Recruiting1
DB01276Exenatide4Completed1
DB01276Exenatide4Recruiting3
DB01276Exenatide4Unknown Status1
DB00158Folic acid4Completed4
DB00158Folic acid4Recruiting1
DB00066Follitropin4Completed1
DB09024Follitropin4Completed1
DB06785Ganirelix4Unknown Status1
DB00644Gonadorelin4Completed1
DB00644Gonadorelin4Not Yet Recruiting1
DB13178Inositol4Completed1
DB13178Inositol4Recruiting1
DB00030Insulin human4Completed1
DB11629Laropiprant4Completed1
DB01006Letrozole4Completed2
DB01006Letrozole4Recruiting1
DB01006Letrozole4Withdrawn1
DB00007Leuprolide4Completed1
DB00007Leuprolide4Recruiting1
DB00007Leuprolide4Terminated1
DB00583Levocarnitine4Completed1
DB11256Levomefolic acid4Completed1
DB06655Liraglutide4Completed9
DB06655Liraglutide4Recruiting1
DB00603Medroxyprogesterone acetate4Withdrawn1
DB00032Menotropins4Completed2
DB00032Menotropins4Terminated1
DB00331Metformin4Completed28
DB00331Metformin4Enrolling by Invitation1
DB00331Metformin4Not Yet Recruiting1
DB00331Metformin4Recruiting4
DB00331Metformin4Suspended1
DB00331Metformin4Terminated3
DB00331Metformin4Unknown Status8
DB00331Metformin4Withdrawn2
DB09242Moxonidine4Completed1
DB00627Niacin4Completed1
DB09389Norgestrel4Completed1
DB11062Octisalate4Completed3
DB09535Octocrylene4Completed3
DB01083Orlistat4Unknown Status2
DB01132Pioglitazone4Completed2
DB01132Pioglitazone4Terminated1
DB00860Prednisolone4Recruiting1
DB00396Progesterone4Completed1
DB00396Progesterone4Withdrawn1
DB01656Roflumilast4Completed2
DB00412Rosiglitazone4Completed1
DB13928Semaglutide4Recruiting1
DB01105Sibutramine4Completed1
DB01105Sibutramine4Unknown Status1
DB00641Simvastatin4Completed1
DB01261Sitagliptin4Completed3
DB00675Tamoxifen4Completed1
DB00273Topiramate4Recruiting1
DB06825Triptorelin4Recruiting2
DB06825Triptorelin4Unknown Status1
DB11094Vitamin D4Completed2
DB11094Vitamin D4Recruiting2
DB11094Vitamin D4Terminated1
DB09145Water4Completed1
DB09321Zinc oxide4Completed3
DB00284AcarboseNot AvailableSuspended1
DB00284AcarboseNot AvailableUnknown Status1
DB01076AtorvastatinNot AvailableCompleted1
DB04115BerberineNot AvailableUnknown Status2
DB00248CabergolineNot AvailableCompleted1
DB01373CalciumNot AvailableCompleted1
DB00050CetrorelixNot AvailableActive Not Recruiting1
DB00097Choriogonadotropin alfaNot AvailableActive Not Recruiting1
DB00097Choriogonadotropin alfaNot AvailableCompleted1
DB00097Choriogonadotropin alfaNot AvailableRecruiting1
DB09126Chorionic Gonadotropin (Human)Not AvailableActive Not Recruiting1
DB09126Chorionic Gonadotropin (Human)Not AvailableCompleted1
DB04272Citric acidNot AvailableCompleted1
DB00882ClomifeneNot AvailableCompleted11
DB00882ClomifeneNot AvailableTerminated2
DB00882ClomifeneNot AvailableUnknown Status4
DB04839Cyproterone acetateNot AvailableCompleted1
DB04839Cyproterone acetateNot AvailableNot Yet Recruiting1
DB04839Cyproterone acetateNot AvailableRecruiting2
DB04839Cyproterone acetateNot AvailableUnknown Status1
DB00151CysteineNot AvailableCompleted1
DB06699DegarelixNot AvailableUnknown Status1
DB01234DexamethasoneNot AvailableCompleted1
DB01234DexamethasoneNot AvailableRecruiting2
DB09341Dextrose, unspecified formNot AvailableCompleted1
DB01119DiazoxideNot AvailableCompleted1
DB01395DrospirenoneNot AvailableCompleted2
DB01395DrospirenoneNot AvailableRecruiting1
DB01395DrospirenoneNot AvailableUnknown Status1
DB00783EstradiolNot AvailableActive Not Recruiting1
DB00783EstradiolNot AvailableCompleted2
DB00783EstradiolNot AvailableRecruiting1
DB00783EstradiolNot AvailableTerminated2
DB00783EstradiolNot AvailableUnknown Status1
DB13956Estradiol valerateNot AvailableCompleted1
DB00977EthinylestradiolNot AvailableCompleted3
DB00977EthinylestradiolNot AvailableNot Yet Recruiting1
DB00977EthinylestradiolNot AvailableRecruiting2
DB00977EthinylestradiolNot AvailableUnknown Status1
DB01039FenofibrateNot AvailableTerminated1
DB00499FlutamideNot AvailableCompleted1
DB00499FlutamideNot AvailableTerminated2
DB00158Folic acidNot AvailableCompleted2
DB09024FollitropinNot AvailableCompleted2
DB00644GonadorelinNot AvailableActive Not Recruiting1
DB00644GonadorelinNot AvailableCompleted1
DB00644GonadorelinNot AvailableUnknown Status1
DB11196InositolNot AvailableCompleted1
DB13178InositolNot AvailableCompleted2
DB13178InositolNot AvailableRecruiting1
DB00030Insulin humanNot AvailableWithdrawn1
DB01006LetrozoleNot AvailableCompleted4
DB01006LetrozoleNot AvailableUnknown Status5
DB00583LevocarnitineNot AvailableCompleted1
DB00583LevocarnitineNot AvailableRecruiting1
DB00367LevonorgestrelNot AvailableRecruiting1
DB00166Lipoic acidNot AvailableCompleted1
DB00166Lipoic acidNot AvailableUnknown Status1
DB00603Medroxyprogesterone acetateNot AvailableCompleted1
DB00603Medroxyprogesterone acetateNot AvailableTerminated2
DB01065MelatoninNot AvailableUnknown Status1
DB00032MenotropinsNot AvailableActive Not Recruiting1
DB00032MenotropinsNot AvailableCompleted1
DB00331MetforminNot AvailableActive Not Recruiting1
DB00331MetforminNot AvailableCompleted23
DB00331MetforminNot AvailableNot Yet Recruiting1
DB00331MetforminNot AvailableRecruiting4
DB00331MetforminNot AvailableSuspended1
DB00331MetforminNot AvailableTerminated1
DB00331MetforminNot AvailableUnknown Status10
DB00393NimodipineNot AvailableCompleted1
DB00727NitroglycerinNot AvailableCompleted1
DB09389NorgestrelNot AvailableCompleted1
DB01132PioglitazoneNot AvailableCompleted1
DB01132PioglitazoneNot AvailableTerminated1
DB00396ProgesteroneNot AvailableActive Not Recruiting1
DB00396ProgesteroneNot AvailableCompleted4
DB00396ProgesteroneNot AvailableTerminated2
DB00481RaloxifeneNot AvailableTerminated1
DB00863RanitidineNot AvailableCompleted1
DB00412RosiglitazoneNot AvailableSuspended1
DB00641SimvastatinNot AvailableCompleted1
DB00641SimvastatinNot AvailableUnknown Status1
DB00052SomatotropinNot AvailableWithdrawn1
DB00421SpironolactoneNot AvailableCompleted2
DB00421SpironolactoneNot AvailableRecruiting1
DB00624TestosteroneNot AvailableCompleted1
DB01284TetracosactideNot AvailableCompleted1
DB01284TetracosactideNot AvailableRecruiting1
DB09536Titanium dioxideNot AvailableRecruiting1
DB06825TriptorelinNot AvailableActive Not Recruiting1
DB06825TriptorelinNot AvailableUnknown Status1
DB09270UbidecarenoneNot AvailableCompleted1
DB11094Vitamin DNot AvailableActive Not Recruiting1
DB11094Vitamin DNot AvailableCompleted1
DB11094Vitamin DNot AvailableRecruiting1
DB09145WaterNot AvailableActive Not Recruiting1
DB09321Zinc oxideNot AvailableRecruiting1