Advanced Non Small Cell Lung Cancer (NSCLC)

Also known as: Advanced Non-Small Cell Lung Cancer (NSCLC) / NSCLC (Advanced Non-small Cell Lung Cancer) / Advanced NSCLC / Nonsmall Cell Lung Cancer, Stage IV / Advanced Non-Small Cell Lung Cancer / Advanced Non Small Cell Lung Cancer / Advanced Nonsmall Cell Lung Cancer / Non-Small Cell Lung Cancer Stage IV / Advanced Non-small-cell Lung Cancer / Non-Small-Cell Lung Cancer Stage IV / Stage IV Non-Small Cell Lung Cancer / Non-small-cell Lung Cancer (NSCLC) Stage IV / Non-small Cell Lung Cancer (NSCLC), Stage IV / Non-small Cell Lung Cancer (NSCLC) Stage IV / Stage 4 Non-small cell lung cancer / Lung Cancer Non-small Cell Stage IV / Stage IV Non-small Cell Lung Cancer (NSCLC) / Metastatic non-small cell lung cancer (disorder) / Non-small cell lung cancer metastatic

DrugDrug NameDrug Description
DB00958CarboplatinA alkylating agent used to treat advanced ovarian cancer.
DB00441GemcitabineA nucleoside metabolic inhibitor used as adjunct therapy in the treatment of certain types of ovarian cancer, non-small cell lung carcinoma, metastatic breast cancer, and as a single agent for pancreatic cancer.
DB15781Hu-rhEGF-rP64k/MontA vaccine used to prevent recurrence of certain lung cancers in patients who have already received cyclophosphamide.
DrugDrug NameTargetType
DB00958CarboplatinDNAtarget
DB00958CarboplatinHigh affinity copper uptake protein 1transporter
DB00958CarboplatinProbable low affinity copper uptake protein 2transporter
DB00958CarboplatinXanthine dehydrogenase/oxidaseenzyme
DB00958CarboplatinMyeloperoxidaseenzyme
DB00958CarboplatinGlutathione S-transferase theta-1enzyme
DB00958CarboplatinMetallothionein-1Aenzyme
DB00958CarboplatinMetallothionein-2enzyme
DB00958CarboplatinSuperoxide dismutase [Cu-Zn]enzyme
DB00958CarboplatinGlutathione S-transferase Penzyme
DB00958CarboplatinGlutathione S-transferase Mu 1enzyme
DB00958CarboplatinNAD(P)H dehydrogenase [quinone] 1enzyme
DB00958CarboplatinCopper-transporting ATPase 1transporter
DB00958CarboplatinCopper-transporting ATPase 2transporter
DB00958CarboplatinATP-binding cassette sub-family G member 2transporter
DB00958CarboplatinCanalicular multispecific organic anion transporter 1transporter
DB00441GemcitabineRibonucleoside-diphosphate reductase large subunittarget
DB00441GemcitabineUMP-CMP kinasetarget
DB00441GemcitabineThymidylate synthasetarget
DB00441GemcitabineCytidine deaminaseenzyme
DB00441GemcitabineDeoxycytidine kinaseenzyme
DB00441GemcitabineP-glycoprotein 1transporter
DB00441GemcitabineMultidrug resistance-associated protein 7transporter
DB00441GemcitabineEquilibrative nucleoside transporter 1transporter
DB00441GemcitabineDNAtarget
DB00441GemcitabineSodium/nucleoside cotransporter 1transporter
DB00441GemcitabineEquilibrative nucleoside transporter 2transporter
DB00441GemcitabineSolute carrier family 28 member 3transporter
DB00441GemcitabineThymidine kinase 2, mitochondrialenzyme
DB00441GemcitabineUMP-CMP kinaseenzyme
DB00441GemcitabineNucleoside diphosphate kinase Aenzyme
DrugDrug NamePhaseStatusCount
DB025942'-Deoxycytidine1Completed1
DB019337-Hydroxystaurosporine1Completed1
DB11881AUY9221Completed1
DB08916Afatinib1Completed1
DB00062Albumin human1Active Not Recruiting1
DB00041Aldesleukin1Active Not Recruiting1
DB11595Atezolizumab1Active Not Recruiting1
DB00928Azacitidine1Completed1
DB11967Binimetinib1Completed1
DB05985Binimetinib1Withdrawn1
DB11967Binimetinib1Withdrawn1
DB00188Bortezomib1Completed1
DB00188Bortezomib1Terminated1
DB16741Bortezomib D-mannitol1Completed1
DB16741Bortezomib D-mannitol1Terminated1
DB11666Buparlisib1Completed1
DB11666Buparlisib1Withdrawn1
DB00958Carboplatin1Completed4
DB00958Carboplatin1Recruiting1
DB00958Carboplatin1Terminated1
DB04849Cediranib1Completed1
DB04849Cediranib1Terminated1
DB00482Celecoxib1Completed1
DB09063Ceritinib1Recruiting1
DB00002Cetuximab1Completed1
DB14547Chloride ion1Active Not Recruiting1
DB14547Chloride ion1Completed1
DB14547Chloride ion1Withdrawn1
DB00515Cisplatin1Active Not Recruiting1
DB00515Cisplatin1Completed2
DB00515Cisplatin1Recruiting1
DB00515Cisplatin1Terminated1
DB00515Cisplatin1Withdrawn1
DB00531Cyclophosphamide1Active Not Recruiting1
DB00531Cyclophosphamide1Completed1
DB00531Cyclophosphamide1Terminated1
DB01262Decitabine1Completed1
DB00004Denileukin diftitox1Completed1
DB01248Docetaxel1Active Not Recruiting1
DB01248Docetaxel1Completed1
DB01248Docetaxel1Recruiting1
DB01248Docetaxel1Terminated1
DB01248Docetaxel1Withdrawn1
DB05928Dovitinib1Terminated1
DB11714Durvalumab1Active Not Recruiting2
DB15631Edodekin alfa1Completed1
DB00530Erlotinib1Completed4
DB00530Erlotinib1Terminated3
DB01590Everolimus1Completed1
DB00990Exemestane1Completed1
DB00099Filgrastim1Terminated1
DB01073Fludarabine1Active Not Recruiting1
DB00441Gemcitabine1Active Not Recruiting1
DB00441Gemcitabine1Completed2
DB00441Gemcitabine1Terminated1
DB00441Gemcitabine1Withdrawn1
DB14865Human interleukin-21Completed1
DB06186Ipilimumab1Terminated1
DB00762Irinotecan1Completed1
DB01167Itraconazole1Active Not Recruiting1
DB16555Lactoferrin1Terminated1
DB14123Menthol1Completed1
DB12303Motolimod1Terminated1
DB15721Natural Killer Cell1Completed1
DB09559Necitumumab1Completed1
DB09035Nivolumab1Active Not Recruiting1
DB09035Nivolumab1Completed1
DB09035Nivolumab1Recruiting1
DB09330Osimertinib1Active Not Recruiting3
DB01229Paclitaxel1Active Not Recruiting1
DB01229Paclitaxel1Completed1
DB01229Paclitaxel1Terminated1
DB09073Palbociclib1Recruiting1
DB00019Pegfilgrastim1Terminated1
DB09037Pembrolizumab1Active Not Recruiting1
DB09037Pembrolizumab1Completed2
DB00642Pemetrexed1Completed4
DB12257Platinum1Active Not Recruiting1
DB12257Platinum1Completed1
DB12257Platinum1Withdrawn1
DB01103Quinacrine1Completed1
DB11870RG-47331Completed1
DB11870RG-47331Terminated2
DB15254RO-5126766 free base1Active Not Recruiting1
DB08877Ruxolitinib1Not Yet Recruiting1
DB14797SEphB4-HSA1Active Not Recruiting1
DB00020Sargramostim1Terminated1
DB12048Savolitinib1Active Not Recruiting1
DB11689Selumetinib1Active Not Recruiting1
DB00877Sirolimus1Completed1
DB00877Sirolimus1Withdrawn1
DB09276Sodium aurothiomalate1Withdrawn1
DB04786Suramin1Completed1
DB11760Talazoparib1Withdrawn1
DB06287Temsirolimus1Completed1
DB00072Trastuzumab1Completed1
DB11771Tremelimumab1Active Not Recruiting1
DB00135Tyrosine1Recruiting1
DB00135Tyrosine1Terminated1
DB00313Valproic acid1Completed1
DB04879Vatalanib1Completed1
DB07232Veliparib1Terminated1
DB00361Vinorelbine1Completed1
DB02546Vorinostat1Terminated1
DB00126Ascorbic acid1 / 2Completed1
DB00995Auranofin1 / 2Recruiting1
DB00928Azacitidine1 / 2Completed1
DB05015Belinostat1 / 2Completed1
DB00112Bevacizumab1 / 2Completed1
DB00958Carboplatin1 / 2Completed3
DB00958Carboplatin1 / 2Recruiting1
DB00958Carboplatin1 / 2Terminated1
DB00002Cetuximab1 / 2Completed2
DB00515Cisplatin1 / 2Not Yet Recruiting1
DB00515Cisplatin1 / 2Unknown Status1
DB05759Cixutumumab1 / 2Completed1
DB12250Cixutumumab1 / 2Completed1
DB01248Docetaxel1 / 2Completed1
DB05719Elesclomol1 / 2Completed1
DB11841Entinostat1 / 2Completed1
DB00530Erlotinib1 / 2Completed4
DB15107Fludeoxyglucose1 / 2Completed1
DB09150Fludeoxyglucose (18F)1 / 2Completed1
DB15030GTI-20401 / 2Completed1
DB00441Gemcitabine1 / 2Completed1
DB06186Ipilimumab1 / 2Recruiting1
DB00762Irinotecan1 / 2Unknown Status1
DB16250Nazartinib1 / 2Active Not Recruiting1
DB06192Nimotuzumab1 / 2Recruiting1
DB06132Nivolumab1 / 2Recruiting1
DB09035Nivolumab1 / 2Recruiting2
DB14844ONC-2011 / 2Withdrawn1
DB09330Osimertinib1 / 2Active Not Recruiting1
DB00526Oxaliplatin1 / 2Recruiting1
DB01229Paclitaxel1 / 2Completed2
DB01229Paclitaxel1 / 2Terminated1
DB12090Patritumab1 / 2Completed1
DB09037Pembrolizumab1 / 2Recruiting2
DB00642Pemetrexed1 / 2Recruiting1
DB12332Rucaparib1 / 2Recruiting1
DB00877Sirolimus1 / 2Recruiting1
DB09256Tegafur1 / 2Unknown Status1
DB02546Vorinostat1 / 2Terminated1
DB11881AUY9222Terminated1
DB12001Abemaciclib2Completed1
DB15568Adagrasib2Recruiting1
DB00062Albumin human2Completed1
DB00041Aldesleukin2Suspended1
DB16640Almonertinib2Not Yet Recruiting1
DB14930Alovudine F-182Completed1
DB12326Antroquinonol2Completed1
DB11595Atezolizumab2Active Not Recruiting2
DB00928Azacitidine2Terminated1
DB00112Bevacizumab2Completed3
DB00112Bevacizumab2Recruiting1
DB00112Bevacizumab2Terminated4
DB00188Bortezomib2Completed4
DB00188Bortezomib2Terminated1
DB16741Bortezomib D-mannitol2Completed3
DB16741Bortezomib D-mannitol2Terminated1
DB11865Brivanib alaninate2Completed1
DB04690Camptothecin2Terminated1
DB14776Camrelizumab2Recruiting1
DB00958Carboplatin2Active Not Recruiting1
DB00958Carboplatin2Completed10
DB00958Carboplatin2Recruiting1
DB00958Carboplatin2Terminated4
DB00958Carboplatin2Unknown Status1
DB00958Carboplatin2Withdrawn1
DB00482Celecoxib2Completed2
DB00002Cetuximab2Completed4
DB14547Chloride ion2Completed1
DB00515Cisplatin2Completed4
DB00515Cisplatin2Recruiting1
DB00515Cisplatin2Withdrawn1
DB05759Cixutumumab2Completed1
DB12250Cixutumumab2Completed1
DB05759Cixutumumab2Terminated1
DB12250Cixutumumab2Terminated1
DB08865Crizotinib2Recruiting1
DB08865Crizotinib2Terminated1
DB00531Cyclophosphamide2Suspended1
DB01254Dasatinib2Completed1
DB01234Dexamethasone2Completed1
DB01248Docetaxel2Completed7
DB01248Docetaxel2Suspended1
DB01248Docetaxel2Terminated5
DB01248Docetaxel2Withdrawn1
DB11714Durvalumab2Recruiting1
DB06423Endostatin2Completed1
DB11841Entinostat2Terminated1
DB15769Envafolimab2Active Not Recruiting1
DB04940Eribulin2Completed1
DB08871Eribulin2Completed1
DB00530Erlotinib2Completed7
DB00530Erlotinib2Suspended1
DB00530Erlotinib2Terminated2
DB00530Erlotinib2Withdrawn1
DB14951Etirinotecan pegol2Completed1
DB16729Favezelimab2Recruiting1
DB00099Filgrastim2Completed1
DB15041Florilglutamic acid F-182Completed1
DB01073Fludarabine2Suspended1
DB09502Fludeoxyglucose (18F)2Completed2
DB13134Fluorine F-182Completed1
DB00317Gefitinib2Completed1
DB00441Gemcitabine2Completed6
DB00441Gemcitabine2Suspended1
DB00441Gemcitabine2Terminated1
DB14865Human interleukin-22Completed1
DB01611Hydroxychloroquine2Completed1
DB00619Imatinib2Completed1
DB05975Iniparib2Completed1
DB00762Irinotecan2Completed1
DB00762Irinotecan2Terminated1
DB09078Lenvatinib2Recruiting1
DB14123Menthol2Completed1
DB00331Metformin2Active Not Recruiting1
DB15483Modified vaccinia ankara2Completed1
DB09049Naloxegol2Active Not Recruiting1
DB06192Nimotuzumab2Terminated1
DB16256Ningetinib2Not Yet Recruiting1
DB09079Nintedanib2Completed1
DB06132Nivolumab2Active Not Recruiting1
DB09035Nivolumab2Active Not Recruiting2
DB06132Nivolumab2Completed1
DB09035Nivolumab2Completed2
DB09035Nivolumab2Recruiting1
DB06132Nivolumab2Terminated1
DB09035Nivolumab2Terminated1
DB06132Nivolumab2Withdrawn1
DB09035Nivolumab2Withdrawn3
DB09330Osimertinib2Recruiting1
DB01229Paclitaxel2Active Not Recruiting1
DB01229Paclitaxel2Completed12
DB01229Paclitaxel2Terminated3
DB13809Paclitaxel poliglumex2Completed1
DB00019Pegfilgrastim2Completed1
DB09037Pembrolizumab2Active Not Recruiting3
DB09037Pembrolizumab2Completed1
DB09037Pembrolizumab2Recruiting3
DB09037Pembrolizumab2Suspended1
DB09037Pembrolizumab2Terminated1
DB00642Pemetrexed2Active Not Recruiting1
DB00642Pemetrexed2Completed2
DB00642Pemetrexed2Recruiting1
DB00642Pemetrexed2Suspended1
DB00642Pemetrexed2Terminated4
DB00642Pemetrexed2Unknown Status1
DB00642Pemetrexed2Withdrawn1
DB15102Pemigatinib2Not Yet Recruiting1
DB12257Platinum2Completed1
DB12257Platinum2Recruiting1
DB06300Ponatinib2Active Not Recruiting1
DB08901Ponatinib2Active Not Recruiting1
DB16422Quavonlimab2Recruiting1
DB11870RG-47332Terminated1
DB13045Racotumomab2Completed1
DB05578Ramucirumab2Withdrawn1
DB14765Rivoceranib2Completed1
DB14765Rivoceranib2Recruiting1
DB06176Romidepsin2Completed1
DB14797SEphB4-HSA2Active Not Recruiting1
DB11805Saracatinib2Completed1
DB15765Sintilimab2Not Yet Recruiting1
DB00398Sorafenib2Completed1
DB04786Suramin2Completed1
DB15106Surufatinib2Recruiting1
DB06584TG40102Completed1
DB04942Tamibarotene2Terminated1
DB06287Temsirolimus2Completed1
DB01041Thalidomide2Recruiting1
DB04960Tipifarnib2Completed1
DB15043Toripalimab2Recruiting2
DB00072Trastuzumab2Completed1
DB00135Tyrosine2Active Not Recruiting1
DB00135Tyrosine2Completed1
DB00135Tyrosine2Terminated2
DB00361Vinorelbine2Completed3
DB00361Vinorelbine2Recruiting1
DB02546Vorinostat2Completed2
DB08916Afatinib2 / 3Active Not Recruiting1
DB00112Bevacizumab2 / 3Completed1
DB00958Carboplatin2 / 3Completed1
DB00002Cetuximab2 / 3Active Not Recruiting1
DB00515Cisplatin2 / 3Completed1
DB01248Docetaxel2 / 3Not Yet Recruiting1
DB01248Docetaxel2 / 3Terminated1
DB12047Ganetespib2 / 3Terminated1
DB00441Gemcitabine2 / 3Completed1
DB09078Lenvatinib2 / 3Not Yet Recruiting1
DB01229Paclitaxel2 / 3Completed1
DB00533Rofecoxib2 / 3Completed1
DB15327Abivertinib3Not Yet Recruiting1
DB15568Adagrasib3Recruiting1
DB05136Bavituximab3Completed1
DB00112Bevacizumab3Completed1
DB14776Camrelizumab3Recruiting1
DB01101Capecitabine3Terminated1
DB00958Carboplatin3Completed2
DB00958Carboplatin3Recruiting2
DB00958Carboplatin3Terminated1
DB11960Carboxyamidotriazole3Completed1
DB00515Cisplatin3Completed3
DB06643Denosumab3Completed1
DB01248Docetaxel3Completed1
DB01248Docetaxel3Recruiting2
DB01248Docetaxel3Terminated2
DB12349Dulanermin3Unknown Status1
DB06423Endostatin3Completed1
DB00530Erlotinib3Completed2
DB00530Erlotinib3Terminated1
DB11741Famitinib3Recruiting1
DB12047Ganetespib3Terminated1
DB00317Gefitinib3Not Yet Recruiting1
DB00441Gemcitabine3Completed4
DB00441Gemcitabine3Terminated1
DB06186Ipilimumab3Active Not Recruiting1
DB09035Nivolumab3Active Not Recruiting1
DB01229Paclitaxel3Completed1
DB01229Paclitaxel3Recruiting1
DB01229Paclitaxel3Terminated1
DB00642Pemetrexed3Completed2
DB00642Pemetrexed3Recruiting1
DB00642Pemetrexed3Terminated1
DB09153Sodium chloride3Completed1
DB06240Tariquidar3Terminated2
DB00135Tyrosine3Not Yet Recruiting1
DB00361Vinorelbine3Completed2
DB00361Vinorelbine3Terminated2
DB01248Docetaxel4Unknown Status1
DB06423Endostatin4Unknown Status1
DB12130Lorlatinib4Active Not Recruiting1
DB00945Acetylsalicylic acidNot AvailableNot Yet Recruiting3
DB16087AlflutinibNot AvailableActive Not Recruiting1
DB14930Alovudine F-18Not AvailableRecruiting1
DB00958CarboplatinNot AvailableCompleted1
DB00515CisplatinNot AvailableCompleted1
DB01234DexamethasoneNot AvailableRecruiting1
DB15351Dihematoporphyrin etherNot AvailableWithdrawn1
DB01248DocetaxelNot AvailableTerminated1
DB00530ErlotinibNot AvailableCompleted1
DB00317GefitinibNot AvailableCompleted1
DB00441GemcitabineNot AvailableTerminated1
DB05296Motexafin lutetiumNot AvailableTerminated1
DB09330OsimertinibNot AvailableNot Yet Recruiting3
DB00642PemetrexedNot AvailableTerminated1
DB00707Porfimer sodiumNot AvailableWithdrawn1