Severe Chronic Obstructive Pulmonary Disease
Also known as: Chronic Obstructive Pulmonary Disease Severe / Chronic, severe Obstructive Pulmonary Disease / Severe chronic obstructive pulmonary disease (disorder)
| Drug | Drug Name | Drug Description |
|---|---|---|
| DB01656 | Roflumilast | A selective phosphodiesterase-4 inhibitor indicated to decrease the risk of exacerbations in patients with severe chronic obstructive pulmonary disease (COPD) and to treat plaque psoriasis. |
| Drug | Drug Name | Target | Type |
|---|---|---|---|
| DB01656 | Roflumilast | Cytochrome P450 3A4 | enzyme |
| DB01656 | Roflumilast | cAMP-specific 3',5'-cyclic phosphodiesterase 4 (PDE4) | target |
| DB01656 | Roflumilast | Cytochrome P450 1A2 | enzyme |
| Drug | Drug Name | Phase | Status | Count |
|---|---|---|---|---|
| DB00207 | Azithromycin | 3 | Recruiting | 1 |
| DB00155 | Citrulline | 3 | Not Yet Recruiting | 1 |
| DB01656 | Roflumilast | 3 | Recruiting | 1 |
| DB01001 | Albuterol | 4 | Completed | 1 |
| DB00169 | Cholecalciferol | 4 | Completed | 1 |
| DB00332 | Ipratropium | 4 | Completed | 1 |
| DB01221 | Ketamine | 4 | Completed | 1 |
| DB00936 | Salicylic acid | 4 | Completed | 1 |
| DB00871 | Terbutaline | 4 | Completed | 1 |