Constipation-predominant Irritable Bowel Syndrome (IBS-C)

Also known as: Constipation Predominant Irritable Bowel Syndrome / IBS, Constipation Predominant / Irritable Bowel Syndrome With Constipation / Irritable Bowel Syndrome Constipation Predominant / Irritable Bowel Syndrome With Constipation (IBS-C) / Constipation-predominant IBS (IBS-C) / Irritable Bowel Syndrome-Constipation / Constipation-Predominant Irritable Bowel Syndrome / Irritable Bowel Syndrome Predominant Constipation / Irritable colon / Colitis mucous / Mucous colitis / Irritable bowel syndrome NOS / IBS / Colon spastic / Spastic colon / Irritable colon syndrome / Functional bowel syndrome / Irritable bowel / Irritable Bowel Syndrome

DrugDrug NameDrug Description
DB08890LinaclotideA guanylate cyclase-C agonist used to treat constipation associated with irritable bowel syndrome or that is idiopathic in nature.
DB01046LubiprostoneA prostaglandin derivative used to treat constipation caused by irritable bowel syndrome and opioid-use.
DB13170PlecanatideA laxative used to treat chronic idiopathic constipation and IBS with constipation.
DB01079TegaserodA serotonin-4 (5-HT4) receptor agonist indicated for the treatment of constipation predominant irritable bowel syndrome (IBS-C) specifically in women under the age of 65. There is currently no safety or efficacy data for use of tegaserol in men.
DB11761TenapanorAn NHE3 inhibitor indicated for the treatment of constipation-predominant irritable bowel syndrome (IBS-C).
DrugDrug NamePhaseStatusCount
DB06777Chenodeoxycholic acid2Completed1
DB05049DDP7332Completed1
DB01175Escitalopram2Completed1
DB08890Linaclotide2Completed3
DB08890Linaclotide2Terminated1
DB00227Lovastatin2Terminated1
DB11097Plantago seed2Terminated1
DB13170Plecanatide2Recruiting1
DB01175Escitalopram2 / 3Not Yet Recruiting1
DB11761Tenapanor2 / 3Completed1
DB08890Linaclotide3Completed4
DB08890Linaclotide3Recruiting1
DB01046Lubiprostone3Completed1
DB11675Mosapride3Terminated1
DB04917Renzapride3Terminated1
DB11761Tenapanor3Completed3
DB04924Itopride4Recruiting1
DB00581Lactulose4Recruiting1
DB08890Linaclotide4Completed1
DB08890Linaclotide4Recruiting1
DB00338Omeprazole4Recruiting1
DB08890LinaclotideNot AvailableCompleted2
DB01046LubiprostoneNot AvailableCompleted1
DB00994NeomycinNot AvailableCompleted1
DB01220RifaximinNot AvailableCompleted1
DB01079TegaserodNot AvailableNo Longer Available1