Recurrent Primary Peritoneal Cancer

Also known as: Recurrent Primary Peritoneal Cavity Cancer

DrugDrug NameDrug Description
DB11793NiraparibA poly-ADP ribose polymerase inhibitor used to treat recurrent epithelial ovarian, fallopian tube, or primary peritoneal cancer responding to platinum based chemotherapy.
DB12332RucaparibA poly (ADP-ribose) polymerase (PARP) inhibitor used to treat recurrent ovarian and prostate cancers in previously treated adults.
DrugDrug NameTargetType
DB11793NiraparibPoly [ADP-ribose] polymerase 1target
DB11793NiraparibPoly [ADP-ribose] polymerase 2target
DB11793NiraparibCarboxylesteraseenzyme
DB11793NiraparibCytochrome P450 1A2enzyme
DB11793NiraparibBroad substrate specificity ATP-binding cassette transporter ABCG2transporter
DB11793NiraparibMultidrug and toxin extrusion protein 1transporter
DB11793NiraparibMultidrug and toxin extrusion protein 2transporter
DB11793NiraparibATP-dependent translocase ABCB1transporter
DB11793NiraparibAlbumincarrier
DB12332RucaparibPoly [ADP-ribose] polymerase 1target
DB12332RucaparibPoly [ADP-ribose] polymerase 2target
DB12332RucaparibProtein mono-ADP-ribosyltransferase PARP3target
DB12332RucaparibCytochrome P450 2D6enzyme
DB12332RucaparibCytochrome P450 1A2enzyme
DB12332RucaparibCytochrome P450 3A4enzyme
DB12332RucaparibATP-dependent translocase ABCB1transporter
DB12332RucaparibBroad substrate specificity ATP-binding cassette transporter ABCG2transporter
DB12332RucaparibMultidrug and toxin extrusion protein 1transporter
DB12332RucaparibMultidrug and toxin extrusion protein 2transporter
DB12332RucaparibSolute carrier family 22 member 1transporter
DB12332RucaparibATP-binding cassette sub-family C member 4transporter
DB12332RucaparibSolute carrier organic anion transporter family member 1B1transporter
DB12332RucaparibSolute carrier organic anion transporter family member 1B3transporter
DB12332RucaparibSolute carrier family 22 member 6transporter
DB12332RucaparibOrganic anion transporter 3transporter
DB12332RucaparibCytochrome P450 3A5enzyme
DB12332RucaparibCytochrome P450 3A7enzyme
DB12332RucaparibCytochrome P450 3A43enzyme
DB12332RucaparibCytochrome P450 2C19enzyme
DB12332RucaparibCytochrome P450 2C9enzyme
DB12332RucaparibCytochrome P450 2C8enzyme
DB12332RucaparibUDP-glucuronosyltransferase 1A1enzyme