Cessation, Smoking

Also known as: Smoking Cessation

DrugDrug NameDrug Description
DB00184NicotineA stimulatory alkaloid found in tobacco products that is often used for the relief of nicotine withdrawal symptoms and as an aid to smoking cessation.
DrugDrug NameTargetType
DB00184NicotineNeuronal acetylcholine receptor subunit alpha-2target
DB00184NicotineNeuronal acetylcholine receptor subunit beta-2target
DB00184NicotineNeuronal acetylcholine receptor subunit alpha-7target
DB00184NicotineNeuronal acetylcholine receptor subunit alpha-4target
DB00184NicotineNeuronal acetylcholine receptor subunit alpha-10target
DB00184NicotineNeuronal acetylcholine receptor subunit alpha-9target
DB00184NicotineCytochrome P450 2A6enzyme
DB00184NicotineCytochrome P450 2E1enzyme
DB00184NicotineCytochrome P450 2A13enzyme
DB00184NicotineCytochrome P450 2B6enzyme
DB00184NicotineNeuronal acetylcholine receptor subunit beta-4target
DB00184NicotineNeuronal acetylcholine receptor subunit alpha-3target
DB00184NicotineNeuronal acetylcholine receptor subunit alpha-5target
DB00184NicotineNeuronal acetylcholine receptor subunit alpha-6target
DB00184NicotineNeuronal acetylcholine receptor subunit beta-3target
DB00184NicotineSolute carrier family 22 member 2transporter
DB00184NicotineSolute carrier family 22 member 1transporter
DB00184NicotineSolute carrier family 22 member 3transporter
DB00184NicotineSolute carrier family 22 member 5transporter
DB00184NicotineSolute carrier family 22 member 4transporter
DB00184NicotineCytochrome P450 1A1enzyme
DB00184NicotineCytochrome P450 1A2enzyme
DB00184NicotineCytochrome P450 2C19enzyme
DB00184NicotineCytochrome P450 2C8enzyme
DB00184NicotineCytochrome P450 2C9enzyme
DB00184NicotineCytochrome P450 2D6enzyme
DB00184NicotineCytochrome P450 3A4enzyme
DB00184NicotineAmine oxidase [flavin-containing] Aenzyme
DB00184NicotineAmine oxidase [flavin-containing] Benzyme
DB00184NicotineCytochrome P450 19A1target
DB00184NicotineCholine O-acetyltransferasetarget
DrugDrug NamePhaseStatusCount
DB01276Exenatide0Active Not Recruiting1
DB00270Isradipine0Recruiting1
DB11895Lenomorelin0Active Not Recruiting1
DB00184Nicotine0Active Not Recruiting1
DB00184Nicotine0Completed1
DB00184Nicotine0Recruiting2
DB00184Nicotine0Terminated1
DB00184Nicotine0Withdrawn1
DB01273Varenicline0Active Not Recruiting1
DB01273Varenicline0Completed2
DB01273Varenicline0Terminated1
DB09028Cytisine1Completed3
DB09028Cytisine1Terminated1
DB00184Nicotine1Completed11
DB00184Nicotine1Recruiting1
DB11062Octisalate1Completed1
DB09535Octocrylene1Completed1
DB01273Varenicline1Completed8
DB09321Zinc oxide1Completed1
DB00490Buspirone1 / 2Completed1
DB09028Cytisine1 / 2Terminated1
DB00514Dextromethorphan1 / 2Recruiting1
DB01276Exenatide1 / 2Completed1
DB04465Lactose1 / 2Completed1
DB00184Nicotine1 / 2Completed3
DB00184Nicotine1 / 2Recruiting2
DB00184Nicotine1 / 2Terminated1
DB01273Varenicline1 / 2Recruiting1
DB00945Acetylsalicylic acid2Active Not Recruiting1
DB01156Bupropion2Completed4
DB01156Bupropion2Not Yet Recruiting2
DB01156Bupropion2Recruiting1
DB00260Cycloserine2Withdrawn1
DB09028Cytisine2Active Not Recruiting1
DB09028Cytisine2Completed1
DB00514Dextromethorphan2Completed1
DB00514Dextromethorphan2Not Yet Recruiting1
DB09045Dulaglutide2Recruiting1
DB11726Encenicline2Terminated1
DB13961Fish oil2Completed1
DB05087Ganaxolone2Completed1
DB01241Gemfibrozil2Completed1
DB01018Guanfacine2Completed1
DB01018Guanfacine2Recruiting1
DB00030Insulin human2Terminated1
DB11867JNJ-393934062Completed2
DB06655Liraglutide2Recruiting1
DB04871Lorcaserin2Completed1
DB04871Lorcaserin2Terminated1
DB00737Meclizine2Completed1
DB14158Microcrystalline cellulose2Completed1
DB01203Nadolol2Completed1
DB06230Nalmefene2Completed1
DB00704Naltrexone2Completed1
DB00184Nicotine2Active Not Recruiting3
DB00184Nicotine2Completed15
DB00184Nicotine2Recruiting2
DB00184Nicotine2Terminated1
DB11062Octisalate2Completed3
DB11062Octisalate2Terminated1
DB11062Octisalate2Unknown Status1
DB09535Octocrylene2Completed3
DB09535Octocrylene2Terminated1
DB09535Octocrylene2Unknown Status1
DB09567Olive oil2Completed1
DB00641Simvastatin2Completed1
DB00877Sirolimus2Completed1
DB09153Sodium chloride2Recruiting1
DB13070Surinabant2Completed1
DB09034Suvorexant2Not Yet Recruiting1
DB01273Varenicline2Completed7
DB01273Varenicline2Recruiting3
DB01273Varenicline2Withdrawn1
DB09321Zinc oxide2Completed3
DB09321Zinc oxide2Terminated1
DB09321Zinc oxide2Unknown Status1
DB01156Bupropion2 / 3Completed1
DB16091EMB-012 / 3Recruiting1
DB04871Lorcaserin2 / 3Terminated1
DB01011Metyrapone2 / 3Recruiting1
DB00184Nicotine2 / 3Completed3
DB00842Oxazepam2 / 3Recruiting1
DB00107Oxytocin2 / 3Recruiting1
DB01273Varenicline2 / 3Active Not Recruiting1
DB01273Varenicline2 / 3Completed3
DB01273Varenicline2 / 3Terminated1
DB01156Bupropion3Active Not Recruiting2
DB01156Bupropion3Completed4
DB01156Bupropion3Recruiting2
DB00260Cycloserine3Completed1
DB09028Cytisine3Completed1
DB09028Cytisine3Recruiting2
DB12125Dianicline3Completed1
DB00184Nicotine3Completed11
DB00184Nicotine3Recruiting1
DB00184Nicotine3Unknown Status2
DB00184Nicotine3Withdrawn1
DB00571Propranolol3Completed1
DB06155Rimonabant3Completed4
DB00734Risperidone3Completed1
DB00273Topiramate3Completed1
DB11699Tropisetron3Completed1
DB01273Varenicline3Active Not Recruiting1
DB01273Varenicline3Completed16
DB01273Varenicline3Recruiting3
DB01273Varenicline3Terminated1
DB01273Varenicline3Unknown Status1
DB00909Zonisamide3Active Not Recruiting1
DB01156Bupropion4Completed10
DB01156Bupropion4Recruiting2
DB00557Hydroxyzine4Completed1
DB00825Levomenthol4Completed1
DB00184Nicotine4Active Not Recruiting4
DB00184Nicotine4Completed36
DB00184Nicotine4Not Yet Recruiting1
DB00184Nicotine4Recruiting2
DB00184Nicotine4Terminated2
DB11062Octisalate4Active Not Recruiting1
DB09535Octocrylene4Active Not Recruiting1
DB00396Progesterone4Completed1
DB00396Progesterone4Not Yet Recruiting1
DB01273Varenicline4Active Not Recruiting2
DB01273Varenicline4Completed29
DB01273Varenicline4Not Yet Recruiting2
DB01273Varenicline4Recruiting3
DB01273Varenicline4Terminated1
DB09321Zinc oxide4Active Not Recruiting1
DB01156BupropionNot AvailableCompleted2
DB01156BupropionNot AvailableUnknown Status3
DB09028CytisineNot AvailableNot Yet Recruiting1
DB00184NicotineNot AvailableActive Not Recruiting4
DB00184NicotineNot AvailableCompleted28
DB00184NicotineNot AvailableNot Yet Recruiting2
DB00184NicotineNot AvailableRecruiting9
DB00184NicotineNot AvailableSuspended1
DB00184NicotineNot AvailableUnknown Status4
DB01273VareniclineNot AvailableActive Not Recruiting1
DB01273VareniclineNot AvailableCompleted12
DB01273VareniclineNot AvailableNot Yet Recruiting1
DB01273VareniclineNot AvailableRecruiting2
DB01273VareniclineNot AvailableUnknown Status2