Bacterial Vaginosis (BV)

Also known as: Vaginosis, Bacterial / Bacterial Vaginosis / Vaginosis bacterial / (Vaginitis &/or vulvovaginitis (& non specified)) or (bacterial vaginosis) or (vulvitis non specified) / Bacterial vaginosis (disorder) / Vaginitis bacterial / Vaginosis bacterial NOS / Vaginitis bacterial NOS / Non-specific vaginitis

DrugDrug NameDrug Description
DB01190ClindamycinA lincosamide antibiotic used to treat serious infections caused by susceptible anaerobic, streptococcal, staphylococcal, and pneumococcal bacteria.
DB00257ClotrimazoleA topical broad-spectrum antifungal agent used for the treatment of a wide variety of dermatophyte infections and candidiasis.
DB01026KetoconazoleA broad spectrum antifungal used to treat seborrheic dermatitis and fungal skin infections.
DB00281LidocaineA local anesthetic used in a wide variety of superficial and invasive procedures.
DB00916MetronidazoleA nitroimidazole used to treat trichomoniasis, amebiasis, inflammatory lesions of rosacea, and bacterial infections, as well as prevent postoperative infections.
DB12834SecnidazoleA nitroimidazole antibiotic used to treat bacterial vaginosis.
DB00911TinidazoleA nitroimidazole used to treat trichomoniasis, giardiasis, amebiasis, and bacterial vaginosis.
DrugDrug NameTargetType
DB01190ClindamycinCytochrome P450 3A4enzyme
DB01190ClindamycinCytochrome P450 3A5enzyme
DB01190ClindamycinAlpha-1-acid glycoprotein 1carrier
DB01190ClindamycinP-glycoprotein 1transporter
DB01190Clindamycin50S ribosomal protein L1target
DB00257ClotrimazoleIntermediate conductance calcium-activated potassium channel protein 4target
DB00257ClotrimazoleCytochrome P450 2D6enzyme
DB00257ClotrimazoleCytochrome P450 2C8enzyme
DB00257ClotrimazoleCytochrome P450 3A4enzyme
DB00257ClotrimazoleCytochrome P450 2B6enzyme
DB00257ClotrimazoleP-glycoprotein 1transporter
DB00257ClotrimazoleCytochrome P450 2A6enzyme
DB00257ClotrimazoleCytochrome P450 2C9enzyme
DB00257ClotrimazoleCytochrome P450 2E1enzyme
DB00257ClotrimazoleCytochrome P450 3A7enzyme
DB00257ClotrimazoleCytochrome P450 51target
DB00257ClotrimazoleNuclear receptor subfamily 1 group I member 2target
DB00257ClotrimazoleHydroxycarboxylic acid receptor 2target
DB00257ClotrimazoleBile salt export pumptransporter
DB00257ClotrimazoleSolute carrier organic anion transporter family member 1B1transporter
DB00257ClotrimazoleSolute carrier organic anion transporter family member 1B3transporter
DB00257ClotrimazoleErgosteroltarget
DB01026KetoconazoleCytochrome P450 3A4enzyme
DB01026KetoconazoleCytochrome P450 2C9enzyme
DB01026KetoconazoleCytochrome P450 2C19enzyme
DB01026KetoconazoleCytochrome P450 3A5enzyme
DB01026KetoconazoleCytochrome P450 1A2enzyme
DB01026KetoconazoleCytochrome P450 2C8enzyme
DB01026KetoconazoleCytochrome P450 1A1enzyme
DB01026KetoconazoleCytochrome P450 2D6enzyme
DB01026KetoconazoleBile salt export pumptransporter
DB01026KetoconazoleP-glycoprotein 1transporter
DB01026KetoconazoleCytochrome P450 11B1, mitochondrialenzyme
DB01026KetoconazoleCytochrome P450 1B1enzyme
DB01026KetoconazoleCytochrome P450 2A6enzyme
DB01026KetoconazoleCytochrome P450 2B6enzyme
DB01026KetoconazoleLanosterol 14-alpha demethylasetarget
DB01026KetoconazoleAndrogen receptortarget
DB01026KetoconazoleSteroid 17-alpha-hydroxylase/17,20 lyasetarget
DB01026KetoconazoleSteroid 21-hydroxylasetarget
DB01026KetoconazolePotassium voltage-gated channel subfamily H member 2target
DB01026KetoconazoleNuclear receptor subfamily 1 group I member 2target
DB01026KetoconazoleNuclear receptor subfamily 1 group I member 3target
DB01026KetoconazoleUDP-glucuronosyltransferase 1-1enzyme
DB01026KetoconazoleUDP-glucuronosyltransferase 2B7enzyme
DB01026KetoconazoleSolute carrier organic anion transporter family member 1B1transporter
DB01026KetoconazoleCytochrome P450 4F12enzyme
DB01026KetoconazoleLeukotriene-B(4) omega-hydroxylase 1enzyme
DB01026KetoconazoleSerum albumincarrier
DB01026KetoconazoleSex hormone-binding globulincarrier
DB01026KetoconazoleCytochrome P450 19A1enzyme
DB01026KetoconazoleUDP-glucuronosyltransferase 1-7enzyme
DB00281LidocaineSodium channel protein type 5 subunit alphatarget
DB00281LidocaineSodium channel protein type 10 subunit alphatarget
DB00281LidocaineEpidermal growth factor receptortarget
DB00281LidocaineSodium channel protein type 9 subunit alphatarget
DB00281LidocaineCytochrome P450 1A2enzyme
DB00281LidocaineCytochrome P450 2D6enzyme
DB00281LidocaineCytochrome P450 3A4enzyme
DB00281LidocaineCytochrome P450 3A5enzyme
DB00281LidocaineCytochrome P450 3A7enzyme
DB00281LidocaineSolute carrier family 22 member 5transporter
DB00281LidocaineP-glycoprotein 1transporter
DB00281LidocaineCytochrome P450 2A6enzyme
DB00281LidocaineCytochrome P450 2B6enzyme
DB00281LidocaineCytochrome P450 2C8enzyme
DB00281LidocaineCytochrome P450 2C9enzyme
DB00281LidocaineSodium channel protein type 4 subunit alphatarget
DB00281LidocaineAlpha-1-acid glycoprotein 1target
DB00281LidocaineAlpha-1-acid glycoprotein 2target
DB00916MetronidazoleOxygen-insensitive NADPH nitroreductasetarget
DB00916MetronidazoleCytochrome P450 2C9enzyme
DB00916MetronidazoleCytochrome P450 3A4enzyme
DB00916MetronidazoleCytochrome P450 2C8enzyme
DB00916MetronidazoleUDP-glucuronosyltransferase 1-1enzyme
DB00916MetronidazoleAnaerobic bacterial DNAtarget
DB00916MetronidazoleProtozoal DNAtarget
DB00916MetronidazoleP-glycoprotein 1transporter
DB00916MetronidazoleCytochrome P450 2A6enzyme
DB00916MetronidazoleCytochrome P450 3A5enzyme
DB00916MetronidazoleCytochrome P450 3A7enzyme
DB00911TinidazoleCytochrome P450 3A4enzyme
DB00911TinidazoleDNAtarget
DB00911TinidazoleBile salt export pumptransporter
DrugDrug NamePhaseStatusCount
DB09130Copper0Terminated1
DB15823Lactobacillus acidophilus0Completed1
DB16540Lactobacillus delbrueckii bulgaricus0Completed1
DB00916Metronidazole0Terminated1
DB00916Metronidazole0Unknown Status1
DB01110Miconazole0Unknown Status1
DB00911Tinidazole0Completed1
DB09321Zinc oxide0Terminated1
DB00916Metronidazole1Completed1
DB00916Metronidazole1Not Yet Recruiting1
DB09130Copper1 / 2Terminated1
DB00916Metronidazole1 / 2Completed1
DB00916Metronidazole1 / 2Terminated1
DB11854Astodrimer2Completed1
DB14547Chloride ion2Unknown Status1
DB16635Glyceryl laurate2Completed1
DB00916Metronidazole2Completed4
DB00916Metronidazole2Terminated1
DB01110Miconazole2Completed1
DB11062Octisalate2Completed1
DB09535Octocrylene2Completed1
DB01220Rifaximin2Terminated1
DB12834Secnidazole2Completed1
DB09153Sodium chloride2Unknown Status1
DB09321Zinc oxide2Completed1
DB11326Boric acid2 / 3Completed1
DB00916Metronidazole2 / 3Completed1
DB00916Metronidazole2 / 3Unknown Status2
DB11145Oxyquinoline2 / 3Completed1
DB00815Sodium lauryl sulfate2 / 3Completed1
DB00681Amphotericin B3Completed1
DB00681Amphotericin B3Unknown Status1
DB11854Astodrimer3Completed4
DB01190Clindamycin3Completed3
DB01190Clindamycin3Unknown Status1
DB00257Clotrimazole3Completed1
DB11615Dequalinium3Completed1
DB01234Dexamethasone3Unknown Status1
DB00196Fluconazole3Completed1
DB01026Ketoconazole3Completed1
DB01026Ketoconazole3Unknown Status1
DB14224Lactobacillus reuteri3Terminated1
DB00916Metronidazole3Completed5
DB00916Metronidazole3Terminated1
DB00916Metronidazole3Unknown Status1
DB00646Nystatin3Unknown Status1
DB12834Secnidazole3Completed2
DB00759Tetracycline3Completed1
DB00759Tetracycline3Unknown Status1
DB00911Tinidazole3Completed2
DB09321Zinc oxide3Completed3
DB00207Azithromycin4Completed1
DB13306Chlorquinaldol4Terminated1
DB01190Clindamycin4Completed2
DB01190Clindamycin4Unknown Status1
DB00257Clotrimazole4Completed1
DB00286Conjugated estrogens4Recruiting1
DB00151Cysteine4Unknown Status1
DB00783Estradiol4Recruiting1
DB00977Ethinylestradiol4Active Not Recruiting1
DB00977Ethinylestradiol4Completed1
DB00977Ethinylestradiol4Unknown Status1
DB00294Etonogestrel4Active Not Recruiting1
DB00294Etonogestrel4Completed1
DB00294Etonogestrel4Unknown Status1
DB15823Lactobacillus acidophilus4Completed1
DB15823Lactobacillus acidophilus4Unknown Status1
DB16540Lactobacillus delbrueckii bulgaricus4Completed1
DB14224Lactobacillus reuteri4Completed1
DB00916Metronidazole4Completed6
DB00916Metronidazole4Recruiting2
DB00916Metronidazole4Terminated1
DB00916Metronidazole4Unknown Status2
DB14678Norethindrone enanthate4Completed1
DB00717Norethisterone4Completed1
DB11062Octisalate4Completed1
DB09535Octocrylene4Completed1
DB11145Oxyquinoline4Recruiting1
DB12487Promestriene4Terminated1
DB00815Sodium lauryl sulfate4Recruiting1
DB00911Tinidazole4Completed1
DB09321Zinc oxide4Completed1
DB09321Zinc oxide4Recruiting1
DB01190ClindamycinNot AvailableCompleted1
DB00916MetronidazoleNot AvailableCompleted6
DB00916MetronidazoleNot AvailableTerminated1
DB01110MiconazoleNot AvailableCompleted1
DB00577ValaciclovirNot AvailableWithdrawn1