Xerosis Cutis

Also known as: Xeroderma / Dryness of skin / Skin dry / Dryness of the skin / Skin dryness / Dry Skin / Pruritus hiemalis / Winter eczema / Senile asteatotic eczema (disorder) / Xerotic eczema / Eczema craquele / Asteatosis / Eczema asteatotic / Winter itch (disorder) / Winter itch / Dry skin dermatitis (disorder) / Asteatotic eczema / Skin xerosis / Asteatosis cutis (disorder) / Other manifestations of vitamin A deficiency / Xeroderma (disorder)

DrugDrug NameDrug Description
DB09357DexpanthenolAn alcoholic analogue of D-pantothenic acid that is used as a supplement or application to support a healthy epithelium and is also used to prevent vitamin deficiency in patients receiving total parenteral nutrition (TPN).
DB11074DimethiconeAn ingredient used to treat dry and irritated eyes.
DB14005Dimethicone 410Dimethicone is approved as a transdermal drug delivery system. Dimethicone 410 is part of the simethicone element in Dow Corning Q7-2242 LVA which is an antifoam.[L2163, L2166] Some OTC's containing...
DB09462GlycerinIt is used as a solvent, emollient, pharmaceutical agent, and sweetening agent.
DB11341IchthammolIchthammol is also referred to as ammonium bituminosulfonate or ammonium bituminosulphonate. It is an ammonium salt of dark sulfonated shale oil (bituminous schists) produced via distillation of the oil followed...
DB14104Linoleic acidNot Annotated
DB00916MetronidazoleA nitroimidazole used to treat trichomoniasis, amebiasis, inflammatory lesions of rosacea, and bacterial infections, as well as prevent postoperative infections.
DB03796Palmitic AcidA fatty used as a food additive and emollient or surfactant in cosmetics.
DB11204PanthenolAn ingredient used in skin, hair care, and nutritional products but is not an approved medication.
DB13964Peanut oilA compound used to lubricate ear wax, as an emollient, and used in laxatives.
DB11058PetrolatumFor use as an over the counter skin protectant [FDA Label]. Commonly used to treat diaper rash and chapped lips [FDA Label] .
DB03088Pidolic acidThere is currently no clinically approved and/or marketed medicine that relies upon pidolic acid as an active ingredient for any formal therapeutic indication. Although pidolic acid may be sold in...
DB15840Pine tarA medication indicated in itchy, inflamed, and flaky skin conditions.
DB03904UreaA keratolytic emollient used to treat hyperkeratotic lesions and moisturize the skin.
DrugDrug NameTargetType
DB09462GlycerinGroup IIE secretory phospholipase A2target
DB09462GlycerinInositol-3-phosphate synthase 1target
DB09462GlycerinAlcohol dehydrogenase 1Btarget
DB09462GlycerinInositol 1,4,5-trisphosphate receptor type 1target
DB09462GlycerinGlycodelintarget
DB09462GlycerinAlpha-N-acetylgalactosaminidasetarget
DB09462GlycerinADP-ribosylation factor 1target
DB09462GlycerinBifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1target
DB09462GlycerinDNA mismatch repair protein MutLtarget
DB09462GlycerinRibonucleoside-diphosphate reductase 1 subunit betatarget
DB09462GlycerinA/G-specific adenine glycosylasetarget
DB09462GlycerintRNA (cytosine(38)-C(5))-methyltransferasetarget
DB09462GlycerinCytochrome P450 2E1enzyme
DB09462GlycerinRetinal dehydrogenase 1enzyme
DB09462GlycerinPeroxisome proliferator-activated receptor deltatarget
DB09462GlycerinMaleylacetoacetate isomerasetarget
DB09462GlycerinAquaporin-7transporter
DB09462GlycerinAquaporin-9transporter
DB09462GlycerinGlycerol uptake facilitator proteintransporter
DB00916MetronidazoleOxygen-insensitive NADPH nitroreductasetarget
DB00916MetronidazoleCytochrome P450 2C9enzyme
DB00916MetronidazoleCytochrome P450 3A4enzyme
DB00916MetronidazoleCytochrome P450 2C8enzyme
DB00916MetronidazoleUDP-glucuronosyltransferase 1-1enzyme
DB00916MetronidazoleAnaerobic bacterial DNAtarget
DB00916MetronidazoleProtozoal DNAtarget
DB00916MetronidazoleP-glycoprotein 1transporter
DB00916MetronidazoleCytochrome P450 2A6enzyme
DB00916MetronidazoleCytochrome P450 3A5enzyme
DB00916MetronidazoleCytochrome P450 3A7enzyme
DB03796Palmitic AcidRhodopsintarget
DB03796Palmitic AcidSerum albumincarrier
DB03796Palmitic AcidPalmitoyl-protein thioesterase 1target
DB03796Palmitic AcidMyelin P2 proteintarget
DB03796Palmitic AcidFatty acid-binding protein, adipocytecarrier
DB03796Palmitic AcidFatty acid-binding protein, epidermalcarrier
DB03796Palmitic AcidGlycodelintarget
DB03796Palmitic AcidFatty acid-binding protein, heartcarrier
DB03796Palmitic AcidHepatocyte nuclear factor 4-gammatarget
DB03796Palmitic AcidLipid binding proteintarget
DB03796Palmitic AcidCytochrome P450 2C8target
DB03796Palmitic AcidTrafficking protein particle complex subunit 3target
DB03796Palmitic AcidFatty acid-binding protein TM_1468target
DB03796Palmitic AcidFatty acid-binding protein, intestinalcarrier
DB03796Palmitic AcidAlpha-lactalbumintarget
DB03796Palmitic AcidPeroxisome proliferator-activated receptor alphatarget
DB03088Pidolic acidAlpha-amylase 2Btarget
DB03088Pidolic acidVascular endothelial growth factor Atarget
DB03088Pidolic acidPancreatic alpha-amylasetarget
DB03088Pidolic acidIg lambda-1 chain C regionstarget
DB03088Pidolic acidIg lambda chain V-II region MGCtarget
DB03088Pidolic acidTrefoil factor 2target
DB03088Pidolic acidCytochrome c2target
DB03088Pidolic acidDisintegrin and metalloproteinase domain-containing protein 28target
DB03088Pidolic acidEndo-1,4-beta-xylanasetarget
DB03088Pidolic acidDissimilatory copper-containing nitrite reductasetarget
DB03088Pidolic acidKeratin-associated protein 5-2target
DB03088Pidolic acidOrexintarget
DB03088Pidolic acidC-C motif chemokine 8target
DB03088Pidolic acidCytochrome c'target
DB03088Pidolic acidPancreatic alpha-amylaseenzyme
DB03904UreaArginase-1target
DB03904UreaCarbonic anhydrase 2target
DB03904UreaCatenin beta-1target
DB03904UreaSulfoxide reductase catalytic subunit YedYtarget
DB03904UreaUrea transporter 2transporter
DB03904UreaUrea transporter 1transporter
DB03904UreaDihydrofolate reductasetarget
DrugDrug NamePhaseStatusCount
DB06768Ammonium lactate3Completed1
DB08818Hyaluronic acid3Completed1
DB03904Urea3Completed1
DB14256Centella asiatica4Unknown Status1
DB00350Minoxidil4Not Yet Recruiting1
DB11058Petrolatum4Unknown Status1