Insufficient Response to Methotrexate

Drug	Drug Name	Drug Description
DB08895	Tofacitinib	A Janus kinase (JAK) inhibitor used to treat rheumatic conditions, such as rheumatoid arthritis and ankylosing spondylitis, and ulcerative colitis.

Drug	Drug Name	Target	Type
DB08895	Tofacitinib	Non-receptor tyrosine-protein kinase TYK2	target
DB08895	Tofacitinib	Cytochrome P450 3A4	enzyme
DB08895	Tofacitinib	Cytochrome P450 2C19	enzyme
DB08895	Tofacitinib	Tyrosine-protein kinase JAK2	target
DB08895	Tofacitinib	Tyrosine-protein kinase JAK1	target
DB08895	Tofacitinib	Tyrosine-protein kinase JAK3	target
DB08895	Tofacitinib	Serum albumin	carrier

Drug	Drug Name	Phase	Status	Count