Acute Lymphoblastic Leukaemia Recurrent

Also known as: Acute, recurrent Lymphoblastic Leukaemia / Acute, recurrent Lymphoblastic Leukemia / Recurrent Acute lymphoblastic leukemia / Acute, relapsed Lymphoblastic Leukemia / Relapsed Acute Lymphoblastic Leukemia / Acute lymphoblastic leukemia recurrent / Relapsed ALL / Acute lymphocytic leukemia recurrent / Acute lymphocytic leukaemia recurrent

DrugDrug NameDrug Description
DB00631ClofarabineA purine nucleoside used to treat relapsed or refractory acute lymphoblastic leukemia in patients 1 to 21 years old.
DB00444TeniposideA cytotoxic drug used as an adjunct for chemotherapy induction in the treatment of refractory childhood acute lymphoblastic leukemia.
DB00541VincristineA vinca alkaloid used to treat acute leukemia, malignant lymphoma, Hodgkin's disease, acute erythraemia, and acute panmyelosis.
DrugDrug NameTargetType
DB00631ClofarabineDNA polymerase alpha catalytic subunittarget
DB00631ClofarabineRibonucleoside-diphosphate reductase large subunittarget
DB00631ClofarabineDeoxycytidine kinaseenzyme
DB00631ClofarabineDNAtarget
DB00631ClofarabineATP-binding cassette sub-family G member 2transporter
DB00444TeniposideDNA topoisomerase 2-alphatarget
DB00444TeniposideCytochrome P450 2C19enzyme
DB00444TeniposideCytochrome P450 2C9enzyme
DB00444TeniposideCytochrome P450 3A4enzyme
DB00444TeniposideMultidrug resistance-associated protein 6transporter
DB00444TeniposideATP-binding cassette sub-family G member 2transporter
DB00444TeniposideCytochrome P450 3A5enzyme
DB00541VincristineTubulin beta chaintarget
DB00541VincristineCytochrome P450 3A4enzyme
DB00541VincristineCytochrome P450 3A5enzyme
DB00541VincristineCytochrome P450 3A7enzyme
DB00541VincristineP-glycoprotein 1transporter
DB00541VincristineCanalicular multispecific organic anion transporter 2transporter
DB00541VincristineSolute carrier family 22 member 3transporter
DB00541VincristineMultidrug resistance-associated protein 1transporter
DB00541VincristineMultidrug resistance-associated protein 7transporter
DB00541VincristineCanalicular multispecific organic anion transporter 1transporter
DB00541VincristineBile salt export pumptransporter
DB00541VincristineATP-binding cassette sub-family G member 2transporter
DB00541VincristineTubulin alpha-4A chaintarget
DB00541VincristineRalA-binding protein 1transporter
DB00541VincristineSolute carrier organic anion transporter family member 1B1transporter
DB00541VincristineSolute carrier organic anion transporter family member 1B3transporter
DrugDrug NamePhaseStatusCount
DB12001Abemaciclib1Recruiting1
DB05812Abiraterone1Recruiting1
DB08916Afatinib1Recruiting1
DB09312Antilymphocyte immunoglobulin (horse)1Active Not Recruiting1
DB00098Antithymocyte immunoglobulin (rabbit)1Active Not Recruiting1
DB08886Asparaginase Erwinia chrysanthemi1Terminated1
DB00023Asparaginase Escherichia coli1Recruiting1
DB00023Asparaginase Escherichia coli1Terminated1
DB09495Avobenzone1Recruiting1
DB00112Bevacizumab1Recruiting1
DB01128Bicalutamide1Recruiting1
DB00188Bortezomib1Recruiting1
DB01008Busulfan1Active Not Recruiting1
DB06772Cabazitaxel1Recruiting1
DB08875Cabozantinib1Recruiting1
DB01101Capecitabine1Recruiting1
DB00958Carboplatin1Recruiting1
DB00482Celecoxib1Recruiting1
DB00631Clofarabine1Active Not Recruiting1
DB06189Clofarabine1Active Not Recruiting1
DB05239Cobimetinib1Recruiting1
DB12483Copanlisib1Recruiting1
DB00531Cyclophosphamide1Active Not Recruiting1
DB00987Cytarabine1Recruiting2
DB00987Cytarabine1Terminated1
DB08912Dabrafenib1Recruiting1
DB11963Dacomitinib1Recruiting1
DB12941Darolutamide1Recruiting1
DB01254Dasatinib1Recruiting1
DB00694Daunorubicin1Recruiting1
DB01262Decitabine1Recruiting1
DB01234Dexamethasone1Recruiting2
DB01234Dexamethasone1Terminated1
DB00380Dexrazoxane1Terminated1
DB00997Doxorubicin1Recruiting2
DB00997Doxorubicin1Terminated1
DB11714Durvalumab1Recruiting1
DB08899Enzalutamide1Recruiting1
DB00530Erlotinib1Recruiting1
DB01590Everolimus1Recruiting1
DB01073Fludarabine1Active Not Recruiting2
DB01073Fludarabine1Recruiting1
DB00544Fluorouracil1Recruiting1
DB00741Hydrocortisone1Recruiting1
DB09054Idelalisib1Recruiting1
DB00619Imatinib1Recruiting1
DB06186Ipilimumab1Active Not Recruiting1
DB06186Ipilimumab1Recruiting1
DB00480Lenalidomide1Active Not Recruiting1
DB09078Lenvatinib1Recruiting1
DB00650Leucovorin1Recruiting1
DB12130Lorlatinib1Recruiting1
DB00678Losartan1Recruiting1
DB00888Mechlorethamine1Active Not Recruiting1
DB00563Methotrexate1Recruiting1
DB00563Methotrexate1Terminated1
DB00688Mycophenolate mofetil1Active Not Recruiting1
DB15721Natural Killer Cell1Active Not Recruiting1
DB11828Neratinib1Recruiting1
DB09035Nivolumab1Active Not Recruiting1
DB09035Nivolumab1Recruiting1
DB09496Octinoxate1Recruiting1
DB09074Olaparib1Recruiting1
DB00526Oxaliplatin1Recruiting1
DB01229Paclitaxel1Recruiting1
DB09073Palbociclib1Recruiting2
DB06603Panobinostat1Recruiting1
DB00059Pegaspargase1Recruiting1
DB09037Pembrolizumab1Recruiting1
DB06366Pertuzumab1Recruiting1
DB11759Pevonedistat1Recruiting1
DB08901Ponatinib1Recruiting1
DB08896Regorafenib1Recruiting1
DB04974Rimiducid1Withdrawn1
DB00073Rituximab1Active Not Recruiting1
DB08877Ruxolitinib1Recruiting1
DB14797SEphB4-HSA1Recruiting1
DB00877Sirolimus1Recruiting1
DB00398Sorafenib1Recruiting2
DB01268Sunitinib1Recruiting1
DB00864Tacrolimus1Active Not Recruiting1
DB08911Trametinib1Recruiting1
DB05773Trastuzumab emtansine1Recruiting1
DB00755Tretinoin1Recruiting1
DB08881Vemurafenib1Recruiting1
DB11581Venetoclax1Recruiting1
DB00541Vincristine1Recruiting2
DB00541Vincristine1Terminated1
DB08828Vismodegib1Recruiting1
DB02546Vorinostat1Active Not Recruiting1
DB02546Vorinostat1Recruiting1
DB09052Blinatumomab1 / 2Recruiting1
DB00531Cyclophosphamide1 / 2Recruiting1
DB00091Cyclosporine1 / 2Recruiting1
DB01234Dexamethasone1 / 2Recruiting2
DB00099Filgrastim1 / 2Recruiting1
DB01073Fludarabine1 / 2Recruiting2
DB00075Muromonab1 / 2Recruiting1
DB00688Mycophenolate mofetil1 / 2Recruiting2
DB09037Pembrolizumab1 / 2Recruiting1
DB08901Ponatinib1 / 2Recruiting1
DB00073Rituximab1 / 2Recruiting1
DB11689Selumetinib1 / 2Recruiting1
DB00877Sirolimus1 / 2Recruiting2
DB13881Tisagenlecleucel1 / 2Recruiting1
DB11581Venetoclax1 / 2Recruiting1
DB02379Beta-D-Glucose2Recruiting2
DB09052Blinatumomab2Recruiting3
DB00188Bortezomib2Recruiting1
DB01008Busulfan2Active Not Recruiting1
DB00631Clofarabine2Recruiting1
DB14681Cortisone2Active Not Recruiting1
DB14681Cortisone2Recruiting2
DB00531Cyclophosphamide2Active Not Recruiting3
DB00531Cyclophosphamide2Recruiting3
DB00987Cytarabine2Active Not Recruiting1
DB00987Cytarabine2Recruiting3
DB01254Dasatinib2Active Not Recruiting1
DB01254Dasatinib2Recruiting1
DB00694Daunorubicin2Active Not Recruiting1
DB00694Daunorubicin2Recruiting1
DB01234Dexamethasone2Active Not Recruiting1
DB01234Dexamethasone2Recruiting1
DB00997Doxorubicin2Active Not Recruiting1
DB00997Doxorubicin2Recruiting1
DB00773Etoposide2Recruiting2
DB00099Filgrastim2Recruiting2
DB15223Flotetuzumab2Not Yet Recruiting1
DB01073Fludarabine2Active Not Recruiting2
DB05889Inotuzumab ozogamicin2Completed1
DB01033Mercaptopurine2Recruiting1
DB00563Methotrexate2Active Not Recruiting2
DB00563Methotrexate2Recruiting3
DB00075Muromonab2Recruiting3
DB00688Mycophenolate mofetil2Active Not Recruiting2
DB06650Ofatumumab2Recruiting2
DB00019Pegfilgrastim2Recruiting2
DB09037Pembrolizumab2Terminated1
DB08901Ponatinib2Recruiting2
DB00635Prednisone2Active Not Recruiting1
DB00635Prednisone2Recruiting2
DB00073Rituximab2Recruiting3
DB14546Sulfate ion2Recruiting2
DB00864Tacrolimus2Active Not Recruiting2
DB04572Thiotepa2Active Not Recruiting2
DB03754Tromethamine2Active Not Recruiting2
DB00541Vincristine2Active Not Recruiting1
DB00541Vincristine2Recruiting4