Fibrodysplasia Ossificans Progressiva (FOP) Completed Phase 1 Trials for Palovarotene (DB05467)

Also known as: FOP / Fibrodysplasia Ossificans Progressiva / Myositis ossificans progressiva, unspecified site / Myositis ossificans progressiva / Progressive myositis ossificans / Progressive myositis ossificans (disorder)

IndicationStatusPhase
DBCOND0086420 (Fibrodysplasia Ossificans Progressiva (FOP))Completed1
clinicaltrials.gov IdentifierTitlePurposeDrugs
NCT04829786Study to Compare the Pharmacokinetics, Safety, and Tolerability Following Administration of Palovarotene in Healthy Japanese and Non-Asian SubjectsTreatment
NCT04829773Study Evaluating the Effect of Food on the Pharmacokinetics of Palovarotene and the Effect of Palovarotene on the Pharmacokinetics of the CYP3A4 Substrate Midazolam in Two Cohorts of Healthy Adult SubjectsTreatment