Trypanosoma Brucei Gambiense; Infection
Also known as: Sleeping Sickness / African Trypanosomiasis / Trypanosomiasis, African / Trypanosoma brucei gambiense infection / African trypanosomiasis, unspecified / African trypanosomiasis (disorder) / Chagas' disease (chronic) with heart involvement / Trypanosomiasis / Trypanosomiasis (disorder) / Trypanosomiasis, unspecified / Trypanosomiasis NOS
| Drug | Drug Name | Drug Description |
|---|---|---|
| DB12265 | Fexinidazole | An orally bioavailable 2-substituted 5-nitroimidazole used to treat early- and late-stage human African trypanosomiasis caused by Trypanosoma brucei gambiense. |
| Drug | Drug Name | Phase | Status | Count |
|---|---|---|---|---|
| DB13086 | Acoziborole | 1 | Completed | 2 |
| DB00514 | Dextromethorphan | 1 | Completed | 1 |
| DB12265 | Fexinidazole | 1 | Completed | 1 |
| DB12265 | Fexinidazole | 1 | Terminated | 1 |
| DB00683 | Midazolam | 1 | Completed | 1 |
| DB06532 | Pafuramidine | 2 | Completed | 2 |
| DB00738 | Pentamidine | 2 | Completed | 1 |
| DB13086 | Acoziborole | 2 / 3 | Completed | 2 |
| DB13086 | Acoziborole | 2 / 3 | Recruiting | 1 |
| DB06243 | Eflornithine | 2 / 3 | Completed | 1 |
| DB06243 | Eflornithine | 2 / 3 | Terminated | 1 |
| DB12265 | Fexinidazole | 2 / 3 | Completed | 1 |
| DB11820 | Nifurtimox | 2 / 3 | Completed | 1 |
| DB11820 | Nifurtimox | 2 / 3 | Terminated | 1 |
| DB06243 | Eflornithine | 3 | Completed | 1 |
| DB06243 | Eflornithine | 3 | Terminated | 1 |
| DB12265 | Fexinidazole | 3 | Completed | 1 |
| DB12864 | Melarsoprol | 3 | Terminated | 1 |
| DB11820 | Nifurtimox | 3 | Completed | 1 |
| DB11820 | Nifurtimox | 3 | Terminated | 1 |