Relapsed/Refractory Multiple Myeloma (RRMM)

Also known as: Relapsed/ Refractory Multiple Myeloma / Relapsed and/or Relapsed-refractory Multiple Myeloma / Relapsed and/or Refractory Multiple Myeloma (RRMM) / Relapse or Refractory Multiple Myeloma / Relapsed, Refractory Multiple Myeloma / Relapsed/Refractory Multiple Myeloma(MM) / Relapsed/Refractory Multiple Myeloma / Relapse and/or Refractory Multiple Myeloma / Relapsed Or Refractory Multiple Myeloma / Relapsed and/or Refractory Multiple Myeloma / Relapsed and Refractory Multiple Myeloma / Relapsed Refractory Multiple Myeloma / Relapsed, Refractory, Multiple Myeloma / Refractory or Relapsed Multiple Myeloma / Refractory, relapsed Multiple Myeloma / Relapsed-Refractory Multiple Myeloma / Plasma cell myeloma refractory

Drug	Drug Name	Drug Description
DB15719	Belantamab mafodotin	An anti B-cell maturation antigen antibody conjugated to a microtubule inhibitor to treat relapsed or refractory multiple myeloma.
DB08889	Carfilzomib	A proteasome inhibitor used either alone or in conjunction with a chemotherapy regimen to treat patients with relapsed or refractory multiple myeloma.
DB16627	Melphalan flufenamide	A melphalan prodrug used to treat relapsed or refractory multiple myeloma.

Drug	Drug Name	Target	Type
DB15719	Belantamab mafodotin	Solute carrier organic anion transporter family member 1B1	transporter
DB15719	Belantamab mafodotin	Solute carrier organic anion transporter family member 1B3	transporter
DB15719	Belantamab mafodotin	Multidrug resistance-associated protein 1	transporter
DB15719	Belantamab mafodotin	ATP-binding cassette sub-family C member 2	transporter
DB15719	Belantamab mafodotin	ATP-binding cassette sub-family C member 3	transporter
DB15719	Belantamab mafodotin	Bile salt export pump	transporter
DB15719	Belantamab mafodotin	ATP-dependent translocase ABCB1	transporter
DB15719	Belantamab mafodotin	Tumor necrosis factor receptor superfamily member 17	target
DB08889	Carfilzomib	ATP-dependent translocase ABCB1	transporter
DB08889	Carfilzomib	Proteasome subunit beta type-5	target
DB08889	Carfilzomib	Proteasome subunit beta type-9	target
DB08889	Carfilzomib	Proteasome subunit beta type-10	target
DB08889	Carfilzomib	Proteasome subunit beta type-8	target
DB08889	Carfilzomib	Proteasome subunit beta type-1	target
DB08889	Carfilzomib	Proteasome subunit beta type-2	target
DB16627	Melphalan flufenamide	Aminopeptidase N	enzyme
DB16627	Melphalan flufenamide	DNA	target

Drug	Drug Name	Phase	Status	Count
DB15719	Belantamab mafodotin	Not Available	Unknown Status	1
DB18180	CT103A	Not Available	Not Yet Recruiting	1
DB00531	Cyclophosphamide	Not Available	Not Yet Recruiting	1
DB00531	Cyclophosphamide	Not Available	Unknown Status	1
DB01234	Dexamethasone	Not Available	Approved for Marketing	1
DB01234	Dexamethasone	Not Available	Completed	1
DB01234	Dexamethasone	Not Available	Recruiting	1
DB01234	Dexamethasone	Not Available	Unknown Status	1
DB06317	Elotuzumab	Not Available	Recruiting	1
DB19016	Equecabtagene autoleucel	Not Available	Not Yet Recruiting	1
DB01073	Fludarabine	Not Available	Not Yet Recruiting	1
DB01073	Fludarabine	Not Available	Unknown Status	1
DB09570	Ixazomib	Not Available	Completed	2
DB09570	Ixazomib	Not Available	Unknown Status	1
DB00480	Lenalidomide	Not Available	Completed	1
DB00480	Lenalidomide	Not Available	Recruiting	1
DB00480	Lenalidomide	Not Available	Unknown Status	1
DB16627	Melphalan flufenamide	Not Available	Approved for Marketing	1
DB08910	Pomalidomide	Not Available	Recruiting	1
DB16678	Talquetamab	Not Available	Approved for Marketing	1
DB16678	Talquetamab	Not Available	No Longer Available	1
DB16655	Teclistamab	Not Available	Approved for Marketing	1
DB00531	Cyclophosphamide	0	Unknown Status	1
DB01073	Fludarabine	0	Unknown Status	1
DB17357	AMG 424	1	Terminated	1
DB12015	Alpelisib	1	Completed	1
DB18881	Anitocabtagene autoleucel	1	Active Not Recruiting	1
DB00098	Antithymocyte immunoglobulin (rabbit)	1	Completed	1
DB00928	Azacitidine	1	Completed	2
DB00188	Bortezomib	1	Completed	1
DB00188	Bortezomib	1	Unknown Status	1
DB00188	Bortezomib	1	Withdrawn	1
DB16741	Bortezomib D-mannitol	1	Unknown Status	1
DB16874	CB-5083	1	Terminated	1
DB18374	Cevostamab	1	Recruiting	1
DB00631	Clofarabine	1	Completed	1
DB00531	Cyclophosphamide	1	Active Not Recruiting	1
DB00531	Cyclophosphamide	1	Recruiting	3
DB00531	Cyclophosphamide	1	Terminated	2
DB00531	Cyclophosphamide	1	Unknown Status	1
DB00531	Cyclophosphamide	1	Withdrawn	1
DB09331	Daratumumab	1	Recruiting	2
DB01234	Dexamethasone	1	Completed	4
DB01234	Dexamethasone	1	Recruiting	2
DB01234	Dexamethasone	1	Terminated	3
DB01234	Dexamethasone	1	Unknown Status	1
DB01234	Dexamethasone	1	Withdrawn	1
DB15395	Elranatamab	1	Recruiting	1
DB15395	Elranatamab	1	Unknown Status	1
DB01073	Fludarabine	1	Active Not Recruiting	1
DB01073	Fludarabine	1	Recruiting	3
DB01073	Fludarabine	1	Terminated	2
DB01073	Fludarabine	1	Unknown Status	1
DB17251	ISB 1342	1	Completed	1
DB18570	ISB 2001	1	Recruiting	1
DB01167	Itraconazole	1	Completed	1
DB09570	Ixazomib	1	Completed	2
DB09570	Ixazomib	1	Terminated	1
DB14943	LGH-447	1	Completed	1
DB00480	Lenalidomide	1	Completed	1
DB00480	Lenalidomide	1	Recruiting	2
DB00480	Lenalidomide	1	Terminated	1
DB17430	MT-0169	1	Terminated	1
DB01204	Mitoxantrone	1	Unknown Status	1
DB16399	Modakafusp alfa	1	Withdrawn	1
DB12005	Nirogacestat	1	Active Not Recruiting	1
DB12005	Nirogacestat	1	Recruiting	1
DB12005	Nirogacestat	1	Terminated	1
DB18740	Nogapendekin alfa	1	Unknown Status	1
DB17254	Pacanalotamab	1	Terminated	1
DB08910	Pomalidomide	1	Completed	1
DB08910	Pomalidomide	1	Recruiting	1
DB08910	Pomalidomide	1	Terminated	1
DB08910	Pomalidomide	1	Withdrawn	1
DB17556	S65487	1	Completed	1
DB11942	Selinexor	1	Completed	1
DB16678	Talquetamab	1	Active Not Recruiting	1
DB17166	Tapotoclax	1	Completed	1
DB16655	Teclistamab	1	Active Not Recruiting	1
DB16655	Teclistamab	1	Recruiting	1
DB06273	Tocilizumab	1	Recruiting	1
DB11581	Venetoclax	1	Completed	1
DB02546	Vorinostat	1	Completed	1
DB15386	ALT-801	1 / 2	Terminated	1
DB11881	AUY922	1 / 2	Completed	1
DB12001	Abemaciclib	1 / 2	Unknown Status	1
DB15719	Belantamab mafodotin	1 / 2	Active Not Recruiting	2
DB15719	Belantamab mafodotin	1 / 2	Terminated	1
DB15719	Belantamab mafodotin	1 / 2	Unknown Status	1
DB06769	Bendamustine	1 / 2	Unknown Status	1
DB00188	Bortezomib	1 / 2	Completed	1
DB00188	Bortezomib	1 / 2	Withdrawn	1
DB15286	CB-1158	1 / 2	Terminated	1
DB08875	Cabozantinib	1 / 2	Completed	1
DB08875	Cabozantinib	1 / 2	Terminated	1
DB08889	Carfilzomib	1 / 2	Recruiting	2
DB08889	Carfilzomib	1 / 2	Terminated	1
DB05239	Cobimetinib	1 / 2	Unknown Status	1
DB00531	Cyclophosphamide	1 / 2	Active Not Recruiting	1
DB00531	Cyclophosphamide	1 / 2	Terminated	1
DB09331	Daratumumab	1 / 2	Recruiting	2
DB09331	Daratumumab	1 / 2	Terminated	2
DB09331	Daratumumab	1 / 2	Unknown Status	1
DB09331	Daratumumab	1 / 2	Withdrawn	1
DB01234	Dexamethasone	1 / 2	Active Not Recruiting	4
DB01234	Dexamethasone	1 / 2	Completed	2
DB01234	Dexamethasone	1 / 2	Not Yet Recruiting	2
DB01234	Dexamethasone	1 / 2	Recruiting	4
DB01234	Dexamethasone	1 / 2	Terminated	2
DB01234	Dexamethasone	1 / 2	Unknown Status	2
DB01234	Dexamethasone	1 / 2	Withdrawn	2
DB06317	Elotuzumab	1 / 2	Active Not Recruiting	1
DB06317	Elotuzumab	1 / 2	Not Yet Recruiting	1
DB16153	Eltanexor	1 / 2	Active Not Recruiting	1
DB13874	Enasidenib	1 / 2	Unknown Status	1
DB12147	Erdafitinib	1 / 2	Unknown Status	1
DB01073	Fludarabine	1 / 2	Terminated	1
DB19015	Forimtamig	1 / 2	Recruiting	1
DB14740	Hyaluronidase	1 / 2	Terminated	1
DB18475	ISB 1442	1 / 2	Recruiting	1
DB06186	Ipilimumab	1 / 2	Terminated	1
DB09570	Ixazomib	1 / 2	Recruiting	1
DB09570	Ixazomib	1 / 2	Unknown Status	1
DB00480	Lenalidomide	1 / 2	Terminated	1
DB16627	Melphalan flufenamide	1 / 2	Terminated	1
DB16370	Mezagitamab	1 / 2	Terminated	1
DB17584	Mezigdomide	1 / 2	Recruiting	1
DB01204	Mitoxantrone	1 / 2	Recruiting	1
DB19038	Narazaciclib	1 / 2	Not Yet Recruiting	1
DB17280	OriCar-017	1 / 2	Recruiting	1
DB01229	Paclitaxel	1 / 2	Terminated	1
DB08910	Pomalidomide	1 / 2	Active Not Recruiting	2
DB08910	Pomalidomide	1 / 2	Not Yet Recruiting	1
DB08910	Pomalidomide	1 / 2	Unknown Status	2
DB08910	Pomalidomide	1 / 2	Withdrawn	1
DB14851	Relatlimab	1 / 2	Active Not Recruiting	1
DB14851	Relatlimab	1 / 2	Not Yet Recruiting	1
DB19065	Renvistobart	1 / 2	Active Not Recruiting	1
DB19065	Renvistobart	1 / 2	Not Yet Recruiting	1
DB11942	Selinexor	1 / 2	Unknown Status	1
DB18753	Sonrotoclax	1 / 2	Recruiting	1
DB16406	Subasumstat	1 / 2	Terminated	1
DB11581	Venetoclax	1 / 2	Completed	1
DB11581	Venetoclax	1 / 2	Unknown Status	1
DB00316	Acetaminophen	2	Active Not Recruiting	1
DB15719	Belantamab mafodotin	2	Not Yet Recruiting	1
DB11967	Binimetinib	2	Completed	1
DB00188	Bortezomib	2	Completed	1
DB16741	Bortezomib D-mannitol	2	Completed	1
DB05147	CYT997	2	Terminated	1
DB08889	Carfilzomib	2	Active Not Recruiting	2
DB08889	Carfilzomib	2	Terminated	1
DB08889	Carfilzomib	2	Unknown Status	1
DB18374	Cevostamab	2	Recruiting	1
DB00531	Cyclophosphamide	2	Completed	4
DB09331	Daratumumab	2	Active Not Recruiting	1
DB09331	Daratumumab	2	Completed	1
DB01234	Dexamethasone	2	Active Not Recruiting	3
DB01234	Dexamethasone	2	Completed	7
DB01234	Dexamethasone	2	Recruiting	1
DB01234	Dexamethasone	2	Terminated	2
DB01234	Dexamethasone	2	Unknown Status	1
DB01075	Diphenhydramine	2	Active Not Recruiting	1
DB05928	Dovitinib	2	Completed	1
DB06317	Elotuzumab	2	Completed	1
DB11718	Encorafenib	2	Completed	1
DB15237	Fluciclovine	2	Recruiting	1
DB06205	Hyaluronidase (human recombinant)	2	Active Not Recruiting	1
DB14811	Isatuximab	2	Active Not Recruiting	1
DB09570	Ixazomib	2	Active Not Recruiting	1
DB09570	Ixazomib	2	Completed	2
DB09570	Ixazomib	2	Terminated	1
DB00480	Lenalidomide	2	Completed	1
DB00959	Methylprednisolone	2	Active Not Recruiting	1
DB00471	Montelukast	2	Active Not Recruiting	1
DB08910	Pomalidomide	2	Active Not Recruiting	2
DB08910	Pomalidomide	2	Completed	3
DB08910	Pomalidomide	2	Terminated	1
DB00635	Prednisone	2	Completed	1
DB18446	RAPA-201	2	Unknown Status	1
DB11942	Selinexor	2	Completed	1
DB11942	Selinexor	2	Recruiting	1
DB01041	Thalidomide	2	Completed	1
DB01041	Thalidomide	2	Unknown Status	1
DB11581	Venetoclax	2	Recruiting	1
DB02546	Vorinostat	2	Completed	1
DB15719	Belantamab mafodotin	3	Withdrawn	1
DB00188	Bortezomib	3	Active Not Recruiting	1
DB00188	Bortezomib	3	Completed	1
DB00188	Bortezomib	3	Recruiting	3
DB16741	Bortezomib D-mannitol	3	Completed	1
DB16741	Bortezomib D-mannitol	3	Recruiting	2
DB08889	Carfilzomib	3	Completed	2
DB08889	Carfilzomib	3	Recruiting	2
DB09331	Daratumumab	3	Recruiting	1
DB09331	Daratumumab	3	Terminated	1
DB01234	Dexamethasone	3	Active Not Recruiting	1
DB01234	Dexamethasone	3	Completed	5
DB01234	Dexamethasone	3	Recruiting	6
DB01234	Dexamethasone	3	Terminated	1
DB06317	Elotuzumab	3	Recruiting	1
DB06205	Hyaluronidase (human recombinant)	3	Terminated	1
DB00480	Lenalidomide	3	Completed	2
DB16627	Melphalan flufenamide	3	Terminated	1
DB17584	Mezigdomide	3	Recruiting	2
DB04977	Plitidepsin	3	Completed	1
DB08910	Pomalidomide	3	Recruiting	5
DB11942	Selinexor	3	Active Not Recruiting	1
DB16678	Talquetamab	3	Recruiting	2
DB16678	Talquetamab	3	Withdrawn	1
DB16655	Teclistamab	3	Recruiting	2
DB11581	Venetoclax	3	Completed	1
DB00188	Bortezomib	4	Completed	1
DB08889	Carfilzomib	4	Active Not Recruiting	1
DB08889	Carfilzomib	4	Completed	1
DB01234	Dexamethasone	4	Active Not Recruiting	1
DB01234	Dexamethasone	4	Completed	1
DB09570	Ixazomib	4	Completed	1
DB00480	Lenalidomide	4	Active Not Recruiting	1
DB00480	Lenalidomide	4	Completed	1