Leiomyosarcoma (LMS)

Also known as: LMS - Leiomyosarcoma / Leiomyosarcomas / Leiomyosarcoma / Leiomyosarcoma (morphologic abnormality) / Leiomyosarcoma NOS / Leiomyosarcoma (disorder)

Drug	Drug Name	Drug Description
DB00398	Sorafenib	A kinase inhibitor used to treat unresectable liver carcinoma, advanced renal carcinoma, and differentiated thyroid carcinoma.

Drug	Drug Name	Target	Type
DB00398	Sorafenib	Serine/threonine-protein kinase B-raf	target
DB00398	Sorafenib	Receptor-type tyrosine-protein kinase FLT3	target
DB00398	Sorafenib	RAF proto-oncogene serine/threonine-protein kinase	target
DB00398	Sorafenib	Vascular endothelial growth factor receptor 3	target
DB00398	Sorafenib	Platelet-derived growth factor receptor beta	target
DB00398	Sorafenib	Mast/stem cell growth factor receptor Kit	target
DB00398	Sorafenib	Vascular endothelial growth factor receptor 2	target
DB00398	Sorafenib	Cytochrome P450 3A4	enzyme
DB00398	Sorafenib	UDP-glucuronosyltransferase 1A9	enzyme
DB00398	Sorafenib	Cytochrome P450 2B6	enzyme
DB00398	Sorafenib	Cytochrome P450 2C8	enzyme
DB00398	Sorafenib	Cytochrome P450 3A5	enzyme
DB00398	Sorafenib	Cytochrome P450 3A7	enzyme
DB00398	Sorafenib	Cytochrome P450 2C9	enzyme
DB00398	Sorafenib	ATP-binding cassette sub-family C member 4	transporter
DB00398	Sorafenib	ATP-dependent translocase ABCB1	transporter
DB00398	Sorafenib	ATP-binding cassette sub-family C member 2	transporter
DB00398	Sorafenib	Broad substrate specificity ATP-binding cassette transporter ABCG2	transporter
DB00398	Sorafenib	Cytochrome P450 1A2	enzyme
DB00398	Sorafenib	Cytochrome P450 2C19	enzyme
DB00398	Sorafenib	Cytochrome P450 2D6	enzyme
DB00398	Sorafenib	UDP-glucuronosyltransferase 1A1	enzyme
DB00398	Sorafenib	RalA-binding protein 1	transporter
DB00398	Sorafenib	Fibroblast growth factor receptor 1	target
DB00398	Sorafenib	Proto-oncogene tyrosine-protein kinase receptor Ret	target
DB00398	Sorafenib	Vascular endothelial growth factor receptor 1	target
DB00398	Sorafenib	Solute carrier organic anion transporter family member 1B1	transporter
DB00398	Sorafenib	Epidermal growth factor receptor	target

Drug	Drug Name	Phase	Status	Count
DB00445	Epirubicin	Not Available	Unknown Status	1
DB08896	Regorafenib	Not Available	Recruiting	1
DB00853	Temozolomide	Not Available	Unknown Status	1
DB12001	Abemaciclib	1 / 2	Not Yet Recruiting	1
DB01248	Docetaxel	1 / 2	Not Yet Recruiting	1
DB00441	Gemcitabine	1 / 2	Not Yet Recruiting	1
DB03619	Deoxycholic acid	2	Terminated	1
DB01234	Dexamethasone	2	Completed	1
DB00380	Dexrazoxane	2	Completed	1
DB01248	Docetaxel	2	Completed	1
DB00997	Doxorubicin	2	Completed	2
DB00997	Doxorubicin	2	Not Yet Recruiting	1
DB08871	Eribulin	2	Active Not Recruiting	1
DB00441	Gemcitabine	2	Completed	1
DB01181	Ifosfamide	2	Not Yet Recruiting	1
DB09035	Nivolumab	2	Completed	1
DB09037	Pembrolizumab	2	Active Not Recruiting	1
DB06233	Ridaforolimus	2	Completed	1
DB05109	Trabectedin	2	Completed	1