Susceptible Bacterial Infections

DrugDrug NameDrug Description
DB00415AmpicillinA penicillin derivative used for the treatment of a variety of infections caused by gram-positive and gram-negative bacteria as well as some anaerobes.
DB00548Azelaic acidA saturated dicarboxylic acid used to treat mild to moderate acne vulgaris.
DB01602BacampicillinAn ampicillin prodrug used to treat various susceptible bacterial infections in the body, such as respiratory infections and skin and subcutaneous tissue infections.
DB00443BetamethasoneA systemic corticosteroid used to relieve inflammation in various conditions, including but not limited to allergic states, dermatologic disorders, gastrointestinal diseases, and hematological disorders.
DB13028BiapenemA carbapenem antibiotic indicated in the treatment of bacterial infections.
DB00833CefaclorA second generation cephalosporin used to treat a wide variety of infections in the body.
DB00456CefalotinA broad-spectrum cephalosporin antibiotic used for the treatment of serious bacterial infections in various locations, such as the urinary tract, skin, bone, and lower respiratory tract.
DB14725Cefamandole nafateA second generation cephalosporin indicated in the prevention of infections during surgery.
DB01327CefazolinA broad-spectrum cephalosporin antibiotic mainly used for the treatment of skin bacterial infections and other moderate to severe bacterial infections in the lung, bone, joint, stomach, blood, heart valve, and urinary tract.
DB00274CefmetazoleA cephalosporin antibiotic used to treat a variety of bacterial infections.
DB09062CefminoxCefminox (INN) is a second generation cephalosporin antibiotic. It is approved for use in Japan.
DB00438CeftazidimeAn injected broad-spectrum third-generation cephalosporin beta-lactam antibiotic used to treat or prevent a variety of bacterial infections, including pneumonia, gynecological infections, bone and joint infections, and septicemia, among others.
DB01212CeftriaxoneA broad-spectrum cephalosporin antibiotic used for the treatment of bacterial infections in various locations, such as in the respiratory tract, skin, soft tissue, and urinary tract.
DB00766Clavulanic acidA beta lactamase inhibitor used to enhance the effectiveness of beta lactam antibiotics.
DB00257ClotrimazoleA topical broad-spectrum antifungal agent used for the treatment of a wide variety of dermatophyte infections and candidiasis.
DB14649Dexamethasone acetateCommonly known as decadron, dexamethasone acetate is a glucocorticosteroid previously marketed in the USA for the treatment of inflammatory respiratory, allergic, autoimmune, and other conditions.[T797,L10695,L14348] Developed in 1957, dexamethasone is...
DB02703Fusidic acidA topical antibacterial agent used to prevent and treat mild to moderate skin infections caused by susceptible bacteria.
DB00281LidocaineA local anesthetic used in a wide variety of superficial and invasive procedures.
DB00256LymecyclineA tetracycline antibiotic used for the treatment of acne vulgaris and other susceptible infections.
DB13260LysozymeAn enzyme indicated in the treatment of gastrointestinal disorders in infants, as well as Herpes zoster and Herpes simplex.
DB00916MetronidazoleA nitroimidazole used to treat trichomoniasis, amebiasis, inflammatory lesions of rosacea, and bacterial infections, as well as prevent postoperative infections.
DB14512Mometasone furoateA corticosteroid used to treat asthma, allergic rhinitis, nasal congestion, nasal polyps, dermatitis, and pruritus.
DB00994NeomycinAn aminoglycoside antibiotic agent used orally and topically to treat a wide variety of infections in the body.
DB00487PefloxacinAn antibiotic used to treat a variety of bacterial infections.
DB01604PivampicillinAn ampicillin prodrug used to treat a variety of infections.
DB00860PrednisoloneA glucocorticoid used to treat adrenocortical insufficiency, inflammatory conditions, and some cancers.
DB11753RifamycinAn antibacterial used to treat traveler's diarrhea.
DrugDrug NameTargetType
DB00415AmpicillinSerum albumincarrier
DB00415AmpicillinSolute carrier family 22 member 5transporter
DB00415AmpicillinSolute carrier family 15 member 1transporter
DB00415AmpicillinSolute carrier family 15 member 2transporter
DB00415AmpicillinPenicillin-binding protein 2atarget
DB00415AmpicillinPenicillin-binding protein 1btarget
DB00415AmpicillinPenicillin-binding protein 3target
DB00415AmpicillinPenicillin-binding protein 1Atarget
DB00415AmpicillinPenicillin-binding protein 2Btarget
DB00415AmpicillinMonocarboxylate transporter 1transporter
DB00415AmpicillinSolute carrier family 15 member 1target
DB00415AmpicillinSolute carrier family 15 member 2target
DB00415AmpicillinAngiopoietin-1 receptortarget
DB00548Azelaic acid3-oxo-5-alpha-steroid 4-dehydrogenase 2target
DB00548Azelaic acidDNA polymerase Itarget
DB00548Azelaic acidThioredoxin reductasetarget
DB00548Azelaic acidTyrosinasetarget
DB00548Azelaic acid3-oxo-5-beta-steroid 4-dehydrogenasetarget
DB01602BacampicillinPenicillin-binding proteintarget
DB00443BetamethasoneGlucocorticoid receptortarget
DB00443BetamethasoneCytochrome P450 3A4enzyme
DB00443BetamethasoneP-glycoprotein 1transporter
DB00443BetamethasoneCytochrome P450 19A1enzyme
DB00443BetamethasoneCytochrome P450 3A5enzyme
DB00443BetamethasoneCytochrome P450 3A7enzyme
DB00443BetamethasoneCytochrome P450 2A6enzyme
DB00443BetamethasoneCytochrome P450 1B1enzyme
DB00443BetamethasoneCytochrome P450 2B6enzyme
DB00443BetamethasoneCytochrome P450 2C8enzyme
DB00443BetamethasoneCytochrome P450 2C9enzyme
DB00443BetamethasoneCytochrome P450 2C19enzyme
DB00443BetamethasoneSerum albumincarrier
DB00443BetamethasoneCorticosteroid-binding globulincarrier
DB00833CefaclorPenicillin-binding protein 1Atarget
DB00833CefaclorSolute carrier family 15 member 1transporter
DB00833CefaclorSolute carrier family 15 member 2transporter
DB00833CefaclorPenicillin-binding protein 3target
DB00833CefaclorMyeloperoxidaseenzyme
DB00833CefaclorSolute carrier family 22 member 8transporter
DB00833CefaclorBile salt export pumptransporter
DB00456CefalotinPenicillin-binding protein 1Atarget
DB00456CefalotinD-alanyl-D-alanine carboxypeptidasetarget
DB00456CefalotinBeta-lactamasetarget
DB00456CefalotinSolute carrier family 22 member 5transporter
DB00456CefalotinSolute carrier family 15 member 1transporter
DB00456CefalotinSolute carrier family 15 member 2transporter
DB00456CefalotinSolute carrier family 22 member 6transporter
DB00456CefalotinSolute carrier family 22 member 8transporter
DB00456CefalotinSolute carrier family 22 member 11transporter
DB00456CefalotinSolute carrier family 22 member 7transporter
DB00456CefalotinPenicillin-binding protein 1Atarget
DB00456CefalotinPenicillin-binding protein 1btarget
DB00456CefalotinPenicillin-binding protein 3target
DB00456CefalotinPenicillin-binding protein 2atarget
DB00456CefalotinPenicillin-binding protein 2Btarget
DB00456CefalotinSerum albumincarrier
DB01327CefazolinSerum paraoxonase/arylesterase 1target
DB01327CefazolinSerum albumincarrier
DB01327CefazolinSolute carrier family 22 member 6transporter
DB01327CefazolinSolute carrier family 22 member 8transporter
DB01327CefazolinSolute carrier family 22 member 11transporter
DB01327CefazolinPenicillin-binding protein 1Atarget
DB01327CefazolinPenicillin-binding protein 1Btarget
DB01327CefazolinPenicillin-binding protein 2target
DB01327CefazolinPenicillin-binding protein 1Ctarget
DB01327CefazolinPeptidoglycan synthase FtsItarget
DB01327CefazolinMultidrug resistance-associated protein 4transporter
DB01327CefazolinThiopurine S-methyltransferaseenzyme
DB01327CefazolinInterleukin-15target
DB01327CefazolinInterleukin-2target
DB00274CefmetazolePenicillin binding protein 2atarget
DB00274CefmetazoleSerum albumincarrier
DB00274CefmetazoleSolute carrier family 15 member 1transporter
DB00274CefmetazoleSolute carrier family 15 member 2transporter
DB00274CefmetazolePenicillin-binding protein 1Atarget
DB00274CefmetazolePenicillin-binding protein 1Btarget
DB00274CefmetazolePeptidoglycan synthase FtsItarget
DB00274CefmetazoleD-alanyl-D-alanine carboxypeptidase DacAtarget
DB00274CefmetazoleD-alanyl-D-alanine carboxypeptidase DacCtarget
DB00438CeftazidimeSolute carrier family 22 member 6transporter
DB00438CeftazidimePeptidoglycan synthase FtsItarget
DB00438CeftazidimePenicillin-binding protein 1Atarget
DB00438CeftazidimePenicillin-binding protein 1Btarget
DB00438CeftazidimePenicillin-binding protein 2target
DB00438CeftazidimeSerum albumincarrier
DB01212CeftriaxoneSerum albumincarrier
DB01212CeftriaxoneSolute carrier family 15 member 1transporter
DB01212CeftriaxoneSolute carrier family 15 member 2transporter
DB01212CeftriaxoneSolute carrier family 22 member 6transporter
DB01212CeftriaxoneSolute carrier family 22 member 8transporter
DB01212CeftriaxoneSolute carrier family 22 member 11transporter
DB01212CeftriaxonePenicillin-binding protein 2Btarget
DB01212CeftriaxoneGlutamine synthetaseenzyme
DB01212CeftriaxoneSolute carrier family 22 member 11target
DB01212CeftriaxoneSolute carrier family 22 member 6target
DB01212CeftriaxoneSolute carrier family 22 member 8target
DB01212CeftriaxoneSolute carrier family 15 member 1target
DB01212CeftriaxoneP-glycoprotein 1transporter
DB00766Clavulanic acidBacterial beta-lactamase enzymestarget
DB00766Clavulanic acidSodium/glucose cotransporter 1transporter
DB00257ClotrimazoleIntermediate conductance calcium-activated potassium channel protein 4target
DB00257ClotrimazoleCytochrome P450 2D6enzyme
DB00257ClotrimazoleCytochrome P450 2C8enzyme
DB00257ClotrimazoleCytochrome P450 3A4enzyme
DB00257ClotrimazoleCytochrome P450 2B6enzyme
DB00257ClotrimazoleP-glycoprotein 1transporter
DB00257ClotrimazoleCytochrome P450 2A6enzyme
DB00257ClotrimazoleCytochrome P450 2C9enzyme
DB00257ClotrimazoleCytochrome P450 2E1enzyme
DB00257ClotrimazoleCytochrome P450 3A7enzyme
DB00257ClotrimazoleCytochrome P450 51target
DB00257ClotrimazoleNuclear receptor subfamily 1 group I member 2target
DB00257ClotrimazoleHydroxycarboxylic acid receptor 2target
DB00257ClotrimazoleBile salt export pumptransporter
DB00257ClotrimazoleSolute carrier organic anion transporter family member 1B1transporter
DB00257ClotrimazoleSolute carrier organic anion transporter family member 1B3transporter
DB00257ClotrimazoleErgosteroltarget
DB14649Dexamethasone acetateGlucocorticoid receptortarget
DB14649Dexamethasone acetateAnnexin A1target
DB14649Dexamethasone acetateNitric oxide synthase, inducibletarget
DB14649Dexamethasone acetateNuclear receptor subfamily 0 group B member 1target
DB14649Dexamethasone acetateCytochrome P450 3A4enzyme
DB14649Dexamethasone acetateCytochrome P450 3A5enzyme
DB14649Dexamethasone acetateCytochrome P450 3A7enzyme
DB14649Dexamethasone acetateBile salt export pumptransporter
DB14649Dexamethasone acetateP-glycoprotein 1transporter
DB14649Dexamethasone acetateCanalicular multispecific organic anion transporter 1transporter
DB14649Dexamethasone acetateSolute carrier organic anion transporter family member 1A2transporter
DB14649Dexamethasone acetateATP-binding cassette sub-family G member 2transporter
DB14649Dexamethasone acetateSteroid 17-alpha-hydroxylase/17,20 lyaseenzyme
DB14649Dexamethasone acetateCytochrome P450 1A1enzyme
DB14649Dexamethasone acetateCytochrome P450 2A6enzyme
DB14649Dexamethasone acetateCytochrome P450 2B6enzyme
DB14649Dexamethasone acetateCytochrome P450 2C19enzyme
DB14649Dexamethasone acetateCytochrome P450 2C8enzyme
DB14649Dexamethasone acetateCytochrome P450 2E1enzyme
DB14649Dexamethasone acetateCytochrome P450 3A43enzyme
DB14649Dexamethasone acetateCytochrome P450 4A11enzyme
DB14649Dexamethasone acetateNuclear receptor subfamily 1 group I member 2target
DB14649Dexamethasone acetateCytochrome P450 11B1, mitochondrialenzyme
DB14649Dexamethasone acetateSerum albumincarrier
DB14649Dexamethasone acetateCorticosteroid 11-beta-dehydrogenase isozyme 2enzyme
DB14649Dexamethasone acetateCorticosteroid 11-beta-dehydrogenase isozyme 1enzyme
DB14649Dexamethasone acetateSolute carrier family 22 member 8transporter
DB02703Fusidic acidChloramphenicol acetyltransferase 3target
DB02703Fusidic acidChloramphenicol acetyltransferasetarget
DB02703Fusidic acidBile salt export pumptransporter
DB02703Fusidic acidCanalicular multispecific organic anion transporter 1transporter
DB02703Fusidic acidElongation factor Gtarget
DB02703Fusidic acidCytochrome P450 2D6enzyme
DB02703Fusidic acidCytochrome P450 3A4enzyme
DB02703Fusidic acidUDP-glucuronosyltransferase 1-1enzyme
DB02703Fusidic acidATP-binding cassette sub-family G member 2transporter
DB02703Fusidic acidSolute carrier organic anion transporter family member 1B1transporter
DB00281LidocaineSodium channel protein type 5 subunit alphatarget
DB00281LidocaineSodium channel protein type 10 subunit alphatarget
DB00281LidocaineEpidermal growth factor receptortarget
DB00281LidocaineSodium channel protein type 9 subunit alphatarget
DB00281LidocaineCytochrome P450 1A2enzyme
DB00281LidocaineCytochrome P450 2D6enzyme
DB00281LidocaineCytochrome P450 3A4enzyme
DB00281LidocaineCytochrome P450 3A5enzyme
DB00281LidocaineCytochrome P450 3A7enzyme
DB00281LidocaineSolute carrier family 22 member 5transporter
DB00281LidocaineP-glycoprotein 1transporter
DB00281LidocaineCytochrome P450 2A6enzyme
DB00281LidocaineCytochrome P450 2B6enzyme
DB00281LidocaineCytochrome P450 2C8enzyme
DB00281LidocaineCytochrome P450 2C9enzyme
DB00281LidocaineSodium channel protein type 4 subunit alphatarget
DB00281LidocaineAlpha-1-acid glycoprotein 1target
DB00281LidocaineAlpha-1-acid glycoprotein 2target
DB00256Lymecycline30S ribosomal protein S4target
DB00916MetronidazoleOxygen-insensitive NADPH nitroreductasetarget
DB00916MetronidazoleCytochrome P450 2C9enzyme
DB00916MetronidazoleCytochrome P450 3A4enzyme
DB00916MetronidazoleCytochrome P450 2C8enzyme
DB00916MetronidazoleUDP-glucuronosyltransferase 1-1enzyme
DB00916MetronidazoleAnaerobic bacterial DNAtarget
DB00916MetronidazoleProtozoal DNAtarget
DB00916MetronidazoleP-glycoprotein 1transporter
DB00916MetronidazoleCytochrome P450 2A6enzyme
DB00916MetronidazoleCytochrome P450 3A5enzyme
DB00916MetronidazoleCytochrome P450 3A7enzyme
DB14512Mometasone furoateGlucocorticoid receptortarget
DB14512Mometasone furoateCytochrome P450 2C8enzyme
DB14512Mometasone furoateProgesterone receptortarget
DB14512Mometasone furoateCytochrome P450 3A4enzyme
DB14512Mometasone furoateCytochrome P450 3A5enzyme
DB00994Neomycin30S ribosomal protein S12target
DB00994Neomycin16S ribosomal RNAtarget
DB00994NeomycinExtracellular calcium-sensing receptortarget
DB00487PefloxacinDNA gyrase subunit Atarget
DB00487PefloxacinDNA topoisomerase 4 subunit Atarget
DB00487PefloxacinDNA topoisomerase 2-alphatarget
DB00487PefloxacinCytochrome P450 1A2enzyme
DB00487PefloxacinDNA topoisomerase 1target
DB01604PivampicillinPenicillin-binding protein 1Atarget
DB00860PrednisoloneCorticosteroid-binding globulincarrier
DB00860PrednisoloneCytochrome P450 3A4enzyme
DB00860PrednisoloneGlucocorticoid receptortarget
DB00860PrednisoloneSolute carrier organic anion transporter family member 1A2transporter
DB00860PrednisoloneP-glycoprotein 1transporter
DB00860PrednisoloneSerum albumincarrier
DB11753RifamycinCytochrome P450 3A4enzyme
DB11753RifamycinCytochrome P450 2C19enzyme
DB11753RifamycinCytochrome P450 2B6enzyme
DB11753RifamycinCytochrome P450 2C8enzyme
DB11753RifamycinCytochrome P450 2C9enzyme
DB11753RifamycinSolute carrier organic anion transporter family member 1A2transporter
DB11753RifamycinSolute carrier organic anion transporter family member 1B1transporter
DB11753RifamycinSolute carrier organic anion transporter family member 1B3transporter
DB11753RifamycinSolute carrier organic anion transporter family member 2A1transporter
DB11753RifamycinSolute carrier organic anion transporter family member 2B1transporter
DB11753RifamycinSerum albumincarrier
DB11753RifamycinDNA-directed RNA polymerase subunit betatarget
DB11753RifamycinDNA-directed RNA polymerase subunit alphatarget
DB11753RifamycinDNA-directed RNA polymerase subunit beta'target
DB11753RifamycinMultidrug and toxin extrusion protein 1transporter
DB11753RifamycinCytochrome P450 1A2enzyme
DB11753RifamycinP-glycoprotein 1transporter
DB11753RifamycinCytochrome P450 2D6enzyme
DrugDrug NamePhaseStatusCount