Onchocerciasis caused by Infection with Onchocerca volvulus

Drug	Drug Name	Drug Description
DB00602	Ivermectin	An anti parasite medication used to treat head lice, onchocerciasis, strongyloidiasis, ascariasis, trichuriasis, and enterobiasis.
DB11431	Moxidectin	Moxidectin is indicated for the treatment of river blindness, also called onchocerciasis, in patients aged 12 years and older. River blindness is caused by a parasitic worm Onchocerca volvulus and...

Drug	Drug Name	Target	Type
DB00602	Ivermectin	P-glycoprotein 1	transporter
DB00602	Ivermectin	Multidrug resistance-associated protein 1	transporter
DB00602	Ivermectin	Canalicular multispecific organic anion transporter 1	transporter
DB00602	Ivermectin	ATP-binding cassette sub-family G member 2	transporter
DB00602	Ivermectin	Cytochrome P450 3A4	enzyme
DB00602	Ivermectin	Solute carrier organic anion transporter family member 1B1	transporter
DB00602	Ivermectin	Solute carrier organic anion transporter family member 1B3	transporter
DB00602	Ivermectin	Cytochrome P450 2D6	enzyme
DB00602	Ivermectin	Cytochrome P450 2E1	enzyme
DB11431	Moxidectin	CYP2B protein	enzyme
DB11431	Moxidectin	Glutamate-gated chloride channel	target
DB11431	Moxidectin	GABA-A gated chloride channel	target
DB11431	Moxidectin	ABC transporters	target

Drug	Drug Name	Phase	Status	Count