NYHA Functional Class II-IV Heart Failure

Drug	Drug Name	Drug Description
DB00331	Metformin	A biguanide antihyperglycemic used in conjunction with diet and exercise for glycemic control in type 2 diabetes mellitus. It is also used off-label for insulin resistance in polycystic ovary syndrome (PCOS).

Drug	Drug Name	Target	Type
DB00331	Metformin	5'-AMP-activated protein kinase subunit beta-1	target
DB00331	Metformin	Solute carrier family 22 member 2	transporter
DB00331	Metformin	Solute carrier family 22 member 1	transporter
DB00331	Metformin	Multidrug and toxin extrusion protein 1	transporter
DB00331	Metformin	Equilibrative nucleoside transporter 4	transporter
DB00331	Metformin	Solute carrier family 22 member 3	transporter
DB00331	Metformin	Multidrug and toxin extrusion protein 2	transporter
DB00331	Metformin	Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial	target
DB00331	Metformin	Glycerol-3-phosphate dehydrogenase [NAD(+)], cytoplasmic	target

Drug	Drug Name	Phase	Status	Count