Acute Bacterial Skin and Skin Structure Infection (ABSSSI)

Also known as: Acute Bacterial Skin and Skin Structure Infections / Acute Bacterial Skin and Skin Structure Infection / Acute Acute Bacterial Skin and Skin Structure Infections / Bacterial infection of skin (disorder) / Skin Diseases, Bacterial / Skin bacterial infection

Drug	Drug Name	Drug Description
DB06590	Ceftaroline fosamil	An antibacterial agent used to treat various bacterial infections, such as acute bacterial skin and skin structure infections and community-acquired bacterial pneumonia.
DB06219	Dalbavancin	An antibacterial used to treat acute bacterial skin and skin structure infections (ABSSSI) caused by susceptible strains of Gram-positive bacteria.
DB11943	Delafloxacin	A fluoroquinolone antibiotic used to treat skin and skin structure infections.
DB12455	Omadacycline	A tetracycline antibiotic used to treat community acquired bacterial pneumonia.
DB14569	Tedizolid	An oxazolidinone class antibiotic that inhibits bacterial protein synthesis and is proven to be effective in the treatment of certain Gram-positive bacterial infections.
DB09042	Tedizolid phosphate	An oxazolidinone class antibiotic that inhibits bacterial protein synthesis and is proven to be effective in the treatment of certain Gram-positive bacterial infections.

Drug	Drug Name	Target	Type
DB06219	Dalbavancin	D-Ala-D-Ala moiety of NAM/NAG peptide subunits of peptidoglycan	target
DB11943	Delafloxacin	UDP-glucuronosyltransferase 1-1	enzyme
DB11943	Delafloxacin	UDP-glucuronosyltransferase 1-3	enzyme
DB11943	Delafloxacin	UDP-glucuronosyltransferase 2B15	enzyme
DB11943	Delafloxacin	DNA topoisomerase 4 subunit A	target
DB11943	Delafloxacin	DNA gyrase subunit A	target
DB11943	Delafloxacin	Cytochrome P450 2E1	enzyme
DB11943	Delafloxacin	Cytochrome P450 2C9	enzyme
DB11943	Delafloxacin	Cytochrome P450 3A4	enzyme
DB11943	Delafloxacin	ATP-binding cassette sub-family B member 5	transporter
DB11943	Delafloxacin	ATP-binding cassette sub-family G member 2	transporter
DB11943	Delafloxacin	Serum albumin	carrier
DB12455	Omadacycline	P-glycoprotein 1	transporter
DB12455	Omadacycline	30S ribosomal protein S3	target
DB12455	Omadacycline	30S ribosomal protein S7	target
DB12455	Omadacycline	30S ribosomal protein S8	target
DB12455	Omadacycline	30S ribosomal protein S19	target
DB12455	Omadacycline	30S ribosomal protein S14	target
DB12455	Omadacycline	16S ribosomal RNA	target
DB12455	Omadacycline	Serum albumin	carrier
DB14569	Tedizolid	23S ribosomal RNA	target
DB14569	Tedizolid	Amine oxidase [flavin-containing] A	enzyme
DB14569	Tedizolid	Amine oxidase [flavin-containing] B	enzyme
DB09042	Tedizolid phosphate	23S ribosomal RNA	target
DB09042	Tedizolid phosphate	Amine oxidase [flavin-containing] A	enzyme
DB09042	Tedizolid phosphate	Amine oxidase [flavin-containing] B	enzyme

Drug	Drug Name	Phase	Status	Count
DB04911	Oritavancin	1	Completed	1
DB01327	Cefazolin	2	Unknown Status	1
DB00601	Linezolid	2	Completed	1
DB04911	Oritavancin	2	Recruiting	1
DB00355	Aztreonam	3	Completed	1
DB04918	Ceftobiprole	3	Completed	1
DB14733	Ceftobiprole medocaril	3	Completed	1
DB02703	Fusidic acid	3	Completed	1
DB16219	Levonadifloxacin	3	Completed	1
DB00601	Linezolid	3	Completed	2
DB09042	Tedizolid phosphate	3	Completed	1
DB00512	Vancomycin	3	Completed	1
DB06590	Ceftaroline fosamil	4	Terminated	1
DB06219	Dalbavancin	4	Completed	2
DB00080	Daptomycin	4	Terminated	1
DB00601	Linezolid	4	Terminated	1
DB04911	Oritavancin	4	Completed	1
DB00512	Vancomycin	4	Terminated	1
DB00682	Warfarin	4	Completed	1
DB06219	Dalbavancin	Not Available	Completed	1
DB00080	Daptomycin	Not Available	Completed	1
DB06149	Teicoplanin	Not Available	Completed	1
DB00512	Vancomycin	Not Available	Completed	1