Refractory Chronic Lymphocytic Leukemia (CLL)

Also known as: Chronic Lymphocytic Leukemia (CLL) - Refractory / CLL, Refractory / Chronic, refractory Lymphocytic leukaemia / Refractory CLL / Refractory Chronic Lymphocytic Leukemia / Chronic lymphocytic leukemia refractory / Chronic Lymphocytic Leukaemia Refractory / Chronic, refractory Lymphocytic Leukemia

DrugDrug NameDrug Description
DB11952DuvelisibAn inhibitor of phosphatidylinositol 3-kinase delta and gamma used to treat relapsed or refractory chronic lymphocytic leukemia or small lymphocytic lymphoma.
DB00480LenalidomideA thalidomide derivative used to treat multiple myeloma and anemia in low to intermediate risk myelodysplastic syndrome.
DB16582Lisocabtagene maraleucelA CAR T-cell therapy for treatment resistant or more severe B-cell lymphomas.
DB06650OfatumumabAn anti-CD20 antibody used for the treatment of chronic lymphocytic leukemia (CLL) in selected patients with certain treatment histories and responsiveness to anticancer medications.
DrugDrug NamePhaseStatusCount
DB00531Cyclophosphamide0Completed1
DB00091Cyclosporine0Completed1
DB01073Fludarabine0Completed1
DB00688Mycophenolate mofetil0Completed1
DB025942'-Deoxycytidine1Completed1
DB12707AR-421Completed1
DB12001Abemaciclib1Terminated1
DB05812Abiraterone1Terminated1
DB08916Afatinib1Terminated1
DB00062Albumin human1Terminated1
DB00041Aldesleukin1Completed1
DB00087Alemtuzumab1Terminated1
DB05220Alisertib1Completed1
DB12442Alvespimycin1Terminated1
DB03496Alvocidib1Completed2
DB03496Alvocidib1Terminated1
DB06467Apolizumab1Completed1
DB09495Avobenzone1Terminated1
DB00928Azacitidine1Active Not Recruiting1
DB06769Bendamustine1Completed1
DB06769Bendamustine1Recruiting2
DB06769Bendamustine1Terminated2
DB00112Bevacizumab1Terminated1
DB01128Bicalutamide1Terminated1
DB00188Bortezomib1Completed2
DB00188Bortezomib1Terminated2
DB16741Bortezomib D-mannitol1Completed1
DB16741Bortezomib D-mannitol1Terminated1
DB11752Bryostatin 11Completed1
DB11666Buparlisib1Terminated1
DB06772Cabazitaxel1Terminated1
DB08875Cabozantinib1Terminated1
DB01101Capecitabine1Terminated1
DB00958Carboplatin1Terminated1
DB08889Carfilzomib1Completed1
DB00482Celecoxib1Terminated1
DB05239Cobimetinib1Terminated1
DB12483Copanlisib1Terminated1
DB00531Cyclophosphamide1Completed2
DB00531Cyclophosphamide1Not Yet Recruiting1
DB00531Cyclophosphamide1Recruiting5
DB00531Cyclophosphamide1Terminated2
DB00531Cyclophosphamide1Unknown Status2
DB00091Cyclosporine1Completed1
DB08912Dabrafenib1Terminated1
DB11963Dacomitinib1Terminated1
DB12941Darolutamide1Terminated1
DB01254Dasatinib1Completed1
DB01254Dasatinib1Terminated1
DB00694Daunorubicin1Terminated1
DB01262Decitabine1Completed1
DB12109Devimistat1Terminated1
DB00380Dexrazoxane1Terminated1
DB00997Doxorubicin1Terminated2
DB11714Durvalumab1Terminated1
DB13874Enasidenib1Terminated1
DB17297Enitociclib1Terminated1
DB11986Entrectinib1Terminated1
DB08899Enzalutamide1Terminated1
DB00530Erlotinib1Terminated1
DB01175Escitalopram1Active Not Recruiting1
DB00773Etoposide1Terminated1
DB01590Everolimus1Completed1
DB01590Everolimus1Terminated1
DB01073Fludarabine1Completed4
DB01073Fludarabine1Not Yet Recruiting1
DB01073Fludarabine1Recruiting5
DB01073Fludarabine1Terminated2
DB01073Fludarabine1Unknown Status2
DB00544Fluorouracil1Terminated1
DB09053Ibrutinib1Active Not Recruiting4
DB09053Ibrutinib1Completed1
DB09053Ibrutinib1Terminated2
DB09054Idelalisib1Terminated1
DB00619Imatinib1Completed1
DB00619Imatinib1Terminated1
DB06186Ipilimumab1Active Not Recruiting1
DB06186Ipilimumab1Completed1
DB06186Ipilimumab1Terminated1
DB00480Lenalidomide1Active Not Recruiting2
DB00480Lenalidomide1Completed3
DB00480Lenalidomide1Unknown Status1
DB09078Lenvatinib1Terminated1
DB00650Leucovorin1Terminated1
DB00166Lipoic acid1Terminated1
DB12130Lorlatinib1Terminated1
DB00678Losartan1Terminated1
DB00888Mechlorethamine1Unknown Status1
DB00331Metformin1Completed1
DB06328Methoxyamine1Completed1
DB00688Mycophenolate mofetil1Completed1
DB00688Mycophenolate mofetil1Unknown Status1
DB15721Natural Killer Cell1Unknown Status1
DB11828Neratinib1Terminated1
DB09035Nivolumab1Active Not Recruiting1
DB09035Nivolumab1Terminated1
DB12191Obatoclax1Terminated2
DB08935Obinutuzumab1Active Not Recruiting1
DB09496Octinoxate1Terminated1
DB06650Ofatumumab1Terminated1
DB09074Olaparib1Terminated1
DB00526Oxaliplatin1Terminated2
DB01229Paclitaxel1Terminated1
DB09073Palbociclib1Terminated1
DB06603Panobinostat1Terminated1
DB09037Pembrolizumab1Terminated1
DB06366Pertuzumab1Terminated1
DB11759Pevonedistat1Active Not Recruiting1
DB08860Pitavastatin1Active Not Recruiting1
DB08901Ponatinib1Terminated1
DB08896Regorafenib1Terminated1
DB00503Ritonavir1Completed1
DB00073Rituximab1Active Not Recruiting1
DB00073Rituximab1Completed3
DB00073Rituximab1Terminated4
DB00073Rituximab1Unknown Status1
DB06176Romidepsin1Active Not Recruiting1
DB06176Romidepsin1Completed1
DB08877Ruxolitinib1Terminated1
DB11965SJG-1361Terminated1
DB11942Selinexor1Active Not Recruiting1
DB00877Sirolimus1Terminated1
DB00398Sorafenib1Completed1
DB00398Sorafenib1Terminated1
DB14546Sulfate ion1Completed1
DB01268Sunitinib1Completed1
DB01268Sunitinib1Terminated1
DB00864Tacrolimus1Unknown Status1
DB06398Tanespimycin1Terminated2
DB17459Therapeutic allogeneic lymphocytes1Completed2
DB13881Tisagenlecleucel1Completed1
DB06273Tocilizumab1Recruiting1
DB05109Trabectedin1Withdrawn1
DB08911Trametinib1Terminated1
DB05773Trastuzumab emtansine1Terminated1
DB00755Tretinoin1Terminated1
DB00313Valproic acid1Completed1
DB08881Vemurafenib1Terminated1
DB11581Venetoclax1Active Not Recruiting1
DB11581Venetoclax1Terminated1
DB11581Venetoclax1Withdrawn1
DB00541Vincristine1Completed1
DB00541Vincristine1Terminated1
DB08828Vismodegib1Terminated1
DB02546Vorinostat1Completed1
DB02546Vorinostat1Terminated1
DB00087Alemtuzumab1 / 2Completed1
DB17746Allogeneic cytomegalovirus-specific cytotoxic T lymphocytes1 / 2Completed1
DB03496Alvocidib1 / 2Completed1
DB06769Bendamustine1 / 2Completed2
DB02379Beta-D-Glucose1 / 2Completed1
DB00262Carmustine1 / 2Completed1
DB00531Cyclophosphamide1 / 2Active Not Recruiting1
DB00531Cyclophosphamide1 / 2Completed2
DB00531Cyclophosphamide1 / 2Unknown Status1
DB00531Cyclophosphamide1 / 2Withdrawn1
DB00091Cyclosporine1 / 2Completed4
DB00987Cytarabine1 / 2Completed1
DB12021Dinaciclib1 / 2Completed1
DB12121Entospletinib1 / 2Completed1
DB00773Etoposide1 / 2Completed1
DB01590Everolimus1 / 2Completed1
DB05076Fenretinide1 / 2Terminated1
DB01073Fludarabine1 / 2Active Not Recruiting1
DB01073Fludarabine1 / 2Completed5
DB01073Fludarabine1 / 2Unknown Status1
DB01073Fludarabine1 / 2Withdrawn1
DB09053Ibrutinib1 / 2Active Not Recruiting1
DB00888Mechlorethamine1 / 2Completed1
DB00688Mycophenolate mofetil1 / 2Completed5
DB15721Natural Killer Cell1 / 2Completed1
DB08935Obinutuzumab1 / 2Active Not Recruiting1
DB08935Obinutuzumab1 / 2Completed1
DB17468Odetiglucan1 / 2Completed1
DB06650Ofatumumab1 / 2Completed1
DB06603Panobinostat1 / 2Completed1
DB00073Rituximab1 / 2Completed3
DB00073Rituximab1 / 2Terminated1
DB00864Tacrolimus1 / 2Completed1
DB13881Tisagenlecleucel1 / 2Recruiting1
DB07232Veliparib1 / 2Completed1
DB11581Venetoclax1 / 2Active Not Recruiting1
DB11703Acalabrutinib2Active Not Recruiting1
DB11703Acalabrutinib2Recruiting2
DB00087Alemtuzumab2Completed2
DB03496Alvocidib2Completed1
DB03496Alvocidib2Terminated1
DB09312Antilymphocyte immunoglobulin (horse)2Completed1
DB09312Antilymphocyte immunoglobulin (horse)2Terminated1
DB00098Antithymocyte immunoglobulin (rabbit)2Completed1
DB00098Antithymocyte immunoglobulin (rabbit)2Terminated1
DB06467Apolizumab2Completed1
DB00394Beclomethasone dipropionate2Completed1
DB02379Beta-D-Glucose2Completed1
DB00112Bevacizumab2Completed1
DB00112Bevacizumab2Withdrawn1
DB00188Bortezomib2Completed1
DB01008Busulfan2Completed1
DB01008Busulfan2Terminated1
DB00262Carmustine2Completed1
DB04849Cediranib2Completed1
DB00531Cyclophosphamide2Completed5
DB00531Cyclophosphamide2Recruiting1
DB00531Cyclophosphamide2Terminated1
DB00531Cyclophosphamide2Withdrawn1
DB00091Cyclosporine2Completed8
DB00091Cyclosporine2Recruiting1
DB00987Cytarabine2Completed1
DB09331Daratumumab2Active Not Recruiting1
DB01254Dasatinib2Completed1
DB01609Deferasirox2Terminated1
DB01234Dexamethasone2Completed1
DB11952Duvelisib2Active Not Recruiting1
DB00773Etoposide2Completed1
DB01590Everolimus2Recruiting1
DB00099Filgrastim2Recruiting1
DB01073Fludarabine2Completed11
DB01073Fludarabine2Recruiting1
DB01073Fludarabine2Terminated2
DB01073Fludarabine2Withdrawn2
DB09053Ibrutinib2Active Not Recruiting2
DB09053Ibrutinib2Completed4
DB09054Idelalisib2Completed1
DB00480Lenalidomide2Active Not Recruiting1
DB00480Lenalidomide2Terminated2
DB00888Mechlorethamine2Completed1
DB01042Melphalan2Completed1
DB14123Menthol2Completed1
DB14123Menthol2Terminated1
DB00563Methotrexate2Completed3
DB00959Methylprednisolone2Completed1
DB00688Mycophenolate mofetil2Completed12
DB00688Mycophenolate mofetil2Recruiting1
DB00688Mycophenolate mofetil2Terminated1
DB00688Mycophenolate mofetil2Withdrawn1
DB01024Mycophenolic acid2Recruiting1
DB09035Nivolumab2Active Not Recruiting1
DB09035Nivolumab2Completed1
DB08935Obinutuzumab2Recruiting1
DB08935Obinutuzumab2Terminated1
DB00904Ondansetron2Completed1
DB09037Pembrolizumab2Completed1
DB08910Pomalidomide2Recruiting1
DB00073Rituximab2Completed3
DB00073Rituximab2Terminated2
DB00073Rituximab2Withdrawn1
DB00877Sirolimus2Completed2
DB00398Sorafenib2Terminated1
DB12369Sotrastaurin2Withdrawn1
DB01268Sunitinib2Completed1
DB01268Sunitinib2Terminated1
DB00864Tacrolimus2Completed7
DB00864Tacrolimus2Terminated1
DB00864Tacrolimus2Withdrawn1
DB15044Tafasitamab2Active Not Recruiting1
DB06287Temsirolimus2Completed1
DB06287Temsirolimus2Terminated1
DB01041Thalidomide2Completed1
DB01041Thalidomide2Terminated1
DB17459Therapeutic allogeneic lymphocytes2Completed1
DB11678Treosulfan2Recruiting1
DB00135Tyrosine2Recruiting2
DB11850Ublituximab2Active Not Recruiting1
DB14989Umbralisib2Active Not Recruiting1
DB11581Venetoclax2Active Not Recruiting1
DB11581Venetoclax2Completed1
DB11581Venetoclax2Recruiting2
DB02546Vorinostat2Completed1
DB00091Cyclosporine3Completed2
DB01073Fludarabine3Completed2
DB00688Mycophenolate mofetil3Completed2
DB00877Sirolimus3Completed1
DB09312Antilymphocyte immunoglobulin (horse)Not AvailableCompleted1
DB00098Antithymocyte immunoglobulin (rabbit)Not AvailableCompleted1
DB01169Arsenic trioxideNot AvailableTerminated1
DB01008BusulfanNot AvailableCompleted1
DB00958CarboplatinNot AvailableCompleted1
DB00262CarmustineNot AvailableCompleted1
DB00531CyclophosphamideNot AvailableCompleted1
DB00091CyclosporineNot AvailableCompleted3
DB00773EtoposideNot AvailableCompleted1
DB00773EtoposideNot AvailableTerminated1
DB00099FilgrastimNot AvailableTerminated2
DB01073FludarabineNot AvailableCompleted3
DB00529FoscarnetNot AvailableCompleted1
DB01004GanciclovirNot AvailableCompleted1
DB14509Lithium carbonateNot AvailableCompleted1
DB01042MelphalanNot AvailableCompleted2
DB00688Mycophenolate mofetilNot AvailableCompleted3
DB00039PaliferminNot AvailableCompleted1
DB06809PlerixaforNot AvailableTerminated2
DB17459Therapeutic allogeneic lymphocytesNot AvailableCompleted2
DB04572ThiotepaNot AvailableCompleted1
DB01610ValganciclovirNot AvailableCompleted1