Active Non-radiographic Axial Spondyloarthritis

Drug	Drug Name	Drug Description
DB11569	Ixekizumab	A monoclonal antibody used to treat moderate to severe plaque psoriasis.
DB15091	Upadacitinib	An oral Janus kinase (JAK)1-selective inhibitor used in the treatment of moderate to severe rheumatoid arthritis, active psoriatic arthritis, ankylosing spondylitis, and severe atopic dermatitis, including in patients who did not respond well to other therapies.

Drug	Drug Name	Target	Type
DB11569	Ixekizumab	Interleukin-17A	target
DB15091	Upadacitinib	Tyrosine-protein kinase JAK1	target
DB15091	Upadacitinib	Cytochrome P450 3A4	enzyme
DB15091	Upadacitinib	Cytochrome P450 2D6	enzyme
DB15091	Upadacitinib	P-glycoprotein 1	transporter
DB15091	Upadacitinib	ATP-binding cassette sub-family G member 2	transporter
DB15091	Upadacitinib	Solute carrier organic anion transporter family member 1B1	transporter

Drug	Drug Name	Phase	Status	Count