- Identifier
- DBSNPE000002, DBSNPE005523
- Drug
- Acetylsalicylic acid (DB00945)
- Interacting Gene/Enzyme
- Cytochrome P450 2C9
- Gene Name
- CYP2C9
- UniProt ID
- P11712
- Defining Change(s)
- Allele Name
- CYP2C9*3
- Genotype(s)
- (A;C) / (C;C)
- Type(s)
- Effect Directly Studied
- Groups
- Non-functional CYP2C9; Decreased CYP2C9
- Description
- Patients with this genotype have reduced metabolism of acetylsalicylic acid.
- References
- Kirchheiner J, Stormer E, Meisel C, Steinbach N, Roots I, Brockmoller J: Influence of CYP2C9 genetic polymorphisms on pharmacokinetics of celecoxib and its metabolites. Pharmacogenetics. 2003 Aug;13(8):473-80. [Article]