Patients with this genotype have reduced metabolism of acetylsalicylic acid.
References
Kirchheiner J, Stormer E, Meisel C, Steinbach N, Roots I, Brockmoller J: Influence of CYP2C9 genetic polymorphisms on pharmacokinetics of celecoxib and its metabolites. Pharmacogenetics. 2003 Aug;13(8):473-80. [Article]