- Identifier
- DBSNPE000046
- Drug
- Citalopram (DB00215)
- Interacting Gene/Enzyme
- Glutamate receptor ionotropic, kainate 2
- Gene Name
- GRIK2
- UniProt ID
- Q13002
- Defining Change(s)
- Allele Name
- Not Available
- Genotype(s)
- (C;C)
- Type(s)
- ADR Directly Studied
- Groups
- Not Available
- Description
- Patients with this genotype have increased frequency of suicidal ideation with citalopram
- References
- Laje G, Paddock S, Manji H, Rush AJ, Wilson AF, Charney D, McMahon FJ: Genetic markers of suicidal ideation emerging during citalopram treatment of major depression. Am J Psychiatry. 2007 Oct;164(10):1530-8. [Article]