- Identifier
- DBSNPE000073
- Drug
- Citalopram (DB00215)
- Interacting Gene/Enzyme
- 5-hydroxytryptamine receptor 2A
- Gene Name
- HTR2A
- UniProt ID
- P28223
- Defining Change(s)
- Allele Name
- Not Available
- Genotype(s)
- (A;A)
- Type(s)
- Effect Directly Studied
- Groups
- Not Available
- Description
- Patients with this genotype have an increased likelihood of responding to citalopram when treating major depressive disorder
- References
- McMahon FJ, Buervenich S, Charney D, Lipsky R, Rush AJ, Wilson AF, Sorant AJ, Papanicolaou GJ, Laje G, Fava M, Trivedi MH, Wisniewski SR, Manji H: Variation in the gene encoding the serotonin 2A receptor is associated with outcome of antidepressant treatment. Am J Hum Genet. 2006 May;78(5):804-14. Epub 2006 Mar 20. [PubMed:16642436]