Pharmacogenomic Effect/ADR for Citalopram (DBSNPE000074)
- Identifier
- DBSNPE000074
- Drug
- Citalopram (DB00215)
- Interacting Gene/Enzyme
- Glutamate receptor ionotropic, kainate 4
- Gene Name
- GRIK4
- UniProt ID
- Q16099
- Defining Change(s)
C Allele rs1954787 - Allele Name
- Not Available
- Genotype(s)
- (C;C)
- Type(s)
- Effect Directly Studied
- Groups
- Not Available
- Description
- Patients with this genotype have an increased likelihood of responding to citalopram when treating major depressive disorder
- References
- Paddock S, Laje G, Charney D, Rush AJ, Wilson AF, Sorant AJ, Lipsky R, Wisniewski SR, Manji H, McMahon FJ: Association of GRIK4 with outcome of antidepressant treatment in the STAR*D cohort. Am J Psychiatry. 2007 Aug;164(8):1181-8. [Article]