Pharmacogenomic Effect/ADR for Citalopram (DBSNPE000074)

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Identifier
DBSNPE000074
Drug
Citalopram (DB00215)
Interacting Gene/Enzyme
Glutamate receptor ionotropic, kainate 4
Gene Name
GRIK4
UniProt ID
Q16099
Defining Change(s)
C Allelers1954787
Allele Name
Not Available
Genotype(s)
(C;C)
Type(s)
Effect Directly Studied
Groups
Not Available
Description
Patients with this genotype have an increased likelihood of responding to citalopram when treating major depressive disorder
References
  1. Paddock S, Laje G, Charney D, Rush AJ, Wilson AF, Sorant AJ, Lipsky R, Wisniewski SR, Manji H, McMahon FJ: Association of GRIK4 with outcome of antidepressant treatment in the STAR*D cohort. Am J Psychiatry. 2007 Aug;164(8):1181-8. [Article]