- Identifier
- DBSNPE000075
- Drug
- Eletriptan (DB00216)
- Interacting Gene/Enzyme
- Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-3
- Gene Name
- GNB3
- UniProt ID
- P16520
- Defining Change(s)
- Allele Name
- Not Available
- Genotype(s)
- (C;T) / (T;T)
- Type(s)
- Effect Directly Studied
- Groups
- Not Available
- Description
- Patients with this genotype have an increased likelihood of responding to elitriptan when treating (condition: cluster headache).
- References
- Schurks M, Kurth T, Stude P, Rimmbach C, de Jesus J, Jonjic M, Diener HC, Rosskopf D: G protein beta3 polymorphism and triptan response in cluster headache. Clin Pharmacol Ther. 2007 Oct;82(4):396-401. Epub 2007 Mar 14. [Article]