Pharmacogenomic Effect/ADR for Pimozide (DBSNPE004739)

Identifier
DBSNPE004739
Drug
Pimozide (DB01100)
Interacting Gene/Enzyme
Cytochrome P450 2D6
Gene Name
CYP2D6
UniProt ID
P10635
Defining Change(s)
124G>Ars5030862
Allele Name
CYP2D6*12
Genotype(s)
Not Available
Type(s)
Effect Inferred
Groups
Non-functional CYP2D6
Description
Poor drug metabolizer, lower dose requirement.
References
  1. Orap® (Pimozide) tablets[package insert]. Sellersville, Pennsylvania: Teva Pharmaceuticals USA; 2011. [Link]