Pharmacogenomic Effect/ADR for Vortioxetine (DBSNPE004957)
- Identifier
- DBSNPE004957
- Drug
- Vortioxetine (DB09068)
- Interacting Gene/Enzyme
- Cytochrome P450 2D6
- Gene Name
- CYP2D6
- UniProt ID
- P10635
- Defining Change(s)
2573insC Not Available - Allele Name
- CYP2D6*21
- Genotype(s)
- Not Available
- Type(s)
- Effect Inferred
- Groups
- Non-functional CYP2D6
- Description
- Poor drug metabolizer, lower maximum dose.
- References
- Trintellix (vortioxetine) tablets[package insert]. Deerfield, Illinois: Takeda Pharmaceuticals America, Inc. 2017. [Link]