- Identifier
- DBSNPE005518
- Drug
- Acetylsalicylic acid (DB00945)
- Interacting Gene/Enzyme
- Cytochrome P450 2C9
- Gene Name
- CYP2C9
- UniProt ID
- P11712
- Defining Change(s)
- Allele Name
- CYP2C9*6
- Genotype(s)
- Not Available
- Type(s)
- Effect Inferred
- Groups
- Non-functional CYP2C9
- Description
- Poor drug metabolizer, lower dose requirements
- References
- Kidd RS, Curry TB, Gallagher S, Edeki T, Blaisdell J, Goldstein JA: Identification of a null allele of CYP2C9 in an African-American exhibiting toxicity to phenytoin. Pharmacogenetics. 2001 Dec;11(9):803-8. [Article]
- Allabi AC, Gala JL, Horsmans Y: CYP2C9, CYP2C19, ABCB1 (MDR1) genetic polymorphisms and phenytoin metabolism in a Black Beninese population. Pharmacogenet Genomics. 2005 Nov;15(11):779-86. [Article]
- The Human Cytochrome P450 (CYP) Allele Nomenclature Database [Link]