Pharmacogenomic Effect/ADR for Acetylsalicylic acid (DBSNPE005524)

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Identifier
DBSNPE005524
Drug
Acetylsalicylic acid (DB00945)
Interacting Gene/Enzyme
Cytochrome P450 2C9
Gene Name
CYP2C9
UniProt ID
P11712
Defining Change(s)
1076T>Crs56165452
Allele Name
CYP2C9*4
Genotype(s)
Not Available
Type(s)
Effect Inferred
Groups
Decreased CYP2C9
Description
Poor drug metabolizer, lower dose requirements
References
  1. Van Booven D, Marsh S, McLeod H, Carrillo MW, Sangkuhl K, Klein TE, Altman RB: Cytochrome P450 2C9-CYP2C9. Pharmacogenet Genomics. 2010 Apr;20(4):277-81. doi: 10.1097/FPC.0b013e3283349e84. [Article]
  2. The Human Cytochrome P450 (CYP) Allele Nomenclature Database [Link]