Pharmacogenomic Effect/ADR for Acetylsalicylic acid (DBSNPE005533)
- Identifier
- DBSNPE005533
- Drug
- Acetylsalicylic acid (DB00945)
- Interacting Gene/Enzyme
- Cytochrome P450 2C9
- Gene Name
- CYP2C9
- UniProt ID
- P11712
- Defining Change(s)
389C>G Not Available - Allele Name
- CYP2C9*26
- Genotype(s)
- Not Available
- Type(s)
- Effect Inferred
- Groups
- Decreased CYP2C9
- Description
- Poor drug metabolizer, lower dose requirements
- References
- Maekawa K, Fukushima-Uesaka H, Tohkin M, Hasegawa R, Kajio H, Kuzuya N, Yasuda K, Kawamoto M, Kamatani N, Suzuki K, Yanagawa T, Saito Y, Sawada J: Four novel defective alleles and comprehensive haplotype analysis of CYP2C9 in Japanese. Pharmacogenet Genomics. 2006 Jul;16(7):497-514. [Article]
- The Human Cytochrome P450 (CYP) Allele Nomenclature Database [Link]