- Identifier
- DBSNPE005626
- Drug
- Codeine (DB00318)
- Interacting Gene/Enzyme
- Cytochrome P450 2D6
- Gene Name
- CYP2D6
- UniProt ID
- P10635
- Defining Change(s)
137insT, 137_138insT | Not Available |
- Allele Name
- CYP2D6*15
- Genotype(s)
- Not Available
- Type(s)
- Effect Inferred
- Groups
- Non-functional CYP2D6
- Description
- Poor drug metabolizer, lower dose requirements
- References
- Sachse C, Brockmoller J, Bauer S, Reum T, Roots I: A rare insertion of T226 in exon 1 of CYP2D6 causes a frameshift and is associated with the poor metabolizer phenotype: CYP2D6*15. Pharmacogenetics. 1996 Jun;6(3):269-72. [PubMed:8807669]
- The Human Cytochrome P450 (CYP) Allele Nomenclature Database [Link]