- Identifier
- DBSNPE005634
- Drug
- Codeine (DB00318)
- Interacting Gene/Enzyme
- Cytochrome P450 2D6
- Gene Name
- CYP2D6
- UniProt ID
- P10635
- Defining Change(s)
- Allele Name
- CYP2D6*42
- Genotype(s)
- Not Available
- Type(s)
- Effect Inferred
- Groups
- Non-functional CYP2D6
- Description
- Poor drug metabolizer, lower dose requirements
- References
- Gaedigk A, Ndjountche L, Gaedigk R, Leeder JS, Bradford LD: Discovery of a novel nonfunctional cytochrome P450 2D6 allele, CYP2D642, in African American subjects. Clin Pharmacol Ther. 2003 Jun;73(6):575-6. [PubMed:12811367]
- The Human Cytochrome P450 (CYP) Allele Nomenclature Database [Link]