Pharmacogenomic Effect/ADR for Codeine (DBSNPE005635)

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Identifier
DBSNPE005635
Drug
Codeine (DB00318)
Interacting Gene/Enzyme
Cytochrome P450 2D6
Gene Name
CYP2D6
UniProt ID
P10635
Defining Change(s)
2950G>CNot Available
Allele Name
CYP2D6*44
Genotype(s)
Not Available
Type(s)
Effect Inferred
Groups
Non-functional CYP2D6
Description
Poor drug metabolizer, lower dose requirements
References
  1. Yamazaki H, Kiyotani K, Tsubuko S, Matsunaga M, Fujieda M, Saito T, Miura J, Kobayashi S, Kamataki T: Two novel haplotypes of CYP2D6 gene in a Japanese population. Drug Metab Pharmacokinet. 2003;18(4):269-71. [Article]
  2. The Human Cytochrome P450 (CYP) Allele Nomenclature Database [Link]