Pharmacogenomic Effect/ADR for Tioguanine (DBSNPE007252)
- Identifier
- DBSNPE007252
- Drug
- Tioguanine (DB00352)
- Interacting Gene/Enzyme
- Thiopurine S-methyltransferase
- Gene Name
- TPMT
- UniProt ID
- P51580
- Defining Change(s)
c.460G>A rs1800460 - Allele Name
- TPMT*3B
- Genotype(s)
- Not Available
- Type(s)
- ADR Inferred
- Groups
- Non-functional TPMT
- Description
- Severe myelosuppression.
- References
- Medical Genetics Summaries: Azathioprine Therapy and TPMT Genotype [Link]