Pharmacogenomic Effect/ADR for Codeine (DBSNPE007304)
- Identifier
- DBSNPE007304
- Drug
- Codeine (DB00318)
- Interacting Gene/Enzyme
- Cytochrome P450 2D6
- Gene Name
- CYP2D6
- UniProt ID
- P10635
- Defining Change(s)
3877G>A rs28371733 - Allele Name
- CYP2D6*4
- Genotype(s)
- Not Available
- Type(s)
- Effect Directly Studied
- Groups
- Not Available
- Description
- The presence of this polymorphism in CYP2D6 results in non-functioning enzyme variant and may be associated with reduced therapeutic response when treated with codeine.
- References
- Not Available