Transketolase
Details
- Name
- Transketolase
- Synonyms
- 2.2.1.1
- Gene Name
- tkt2
- UniProtKB Entry
- A0A6L7H165TrEMBL
- Organism
- Bacillus anthracis
- NCBI Taxonomy ID
- 1392
- Amino acid sequence
>lcl|BSEQ0017401|Transketolase MSHSIEQLSINTIRTLSIDAIEKANSGHPGMPMGAAPMAYTLWTQFMKHNPNNPTWFNRD RFVLSAGHGSMLLYSLLHLSGYDVTMDDLKNFRQWGSKTPGHPEYGHTAGVDATTGPLGQ GIATAVGMAMAERHLAAKYNRDAYNIVDHYTYAICGDGDLMEGVSAEASSLAAHLQLGRL VVLYDSNDISLDGDLNRSFSESVEDRYKAYGWQVIRVEDGNDIEAIAKAIEEAKADEKRP TLIEVRTTIGFGSPNKSGKSASHGSPLGVEETKLTKEAYAWTAEQDFHVAEEVYENFRKT VQDVGETAQAEWNTMLGEYAQAYPELANELQAAMNGLLPEGWEQNLPTYELGSKAATRNS SGAVINAIAESVPSFFGGSADLAGSNKTYMNNEKDFTRDDYSGKNIWYGVREFAMGAAMN GIALHGGLKTYGGTFFVFSDYLRPAIRLAALMQLPVTYVFTHDSIAVGEDGPTHEPIEQL AALRAMPNVSVIRPADGNESVAAWRLALESTNKPTALVLTRQDLPTLEGAKDDTYEKVAK GAYVVSASKKETADVILLATGSEVSLAVEAQKALAVDGVDASVVSMPSMDRFEAQTAEYK ESVLPKAVTKRFAIEMGATFGWHRYVGLEGDVLGIDTFGASAPGEKIMEEYGFTVENVVR KVKEML
- Number of residues
- 666
- Molecular Weight
- 72408.685
- Theoretical pI
- 4.71
- GO Classification
- Functionsmetal ion binding / transketolase activity
- General Function
- Transketolase activity
- Specific Function
- Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.
- Pfam Domain Function
- Signal Regions
- Not Available
- Transmembrane Regions
- Not Available
- Cellular Location
- Not Available
- Gene sequence
>lcl|BSEQ0017402|Transketolase (tkt2) ATGTCACATTCAATCGAACAACTTTCTATCAACACGATTCGCACATTATCCATCGATGCG ATTGAAAAAGCAAACTCTGGTCACCCAGGAATGCCAATGGGTGCAGCACCAATGGCTTAT ACATTATGGACTCAATTTATGAAACACAATCCAAATAACCCAACGTGGTTTAACCGTGAT CGTTTCGTATTATCTGCAGGTCATGGTTCAATGTTATTATACAGCCTACTTCACCTATCT GGTTATGATGTAACAATGGATGACTTAAAGAACTTCCGTCAATGGGGAAGCAAAACTCCA GGGCATCCTGAGTACGGTCATACAGCTGGTGTAGATGCAACTACTGGTCCACTTGGACAA GGTATTGCAACTGCTGTAGGTATGGCAATGGCAGAAAGACATTTAGCTGCTAAATATAAC CGTGATGCGTATAATATAGTAGATCATTATACATACGCTATTTGTGGTGATGGAGATTTA ATGGAAGGCGTTTCTGCTGAAGCATCTTCATTAGCTGCTCATTTACAATTAGGTCGTCTT GTTGTGCTTTATGATTCAAACGATATTTCATTAGATGGCGATTTAAATCGTTCATTCTCT GAAAGTGTAGAAGATCGTTACAAAGCATACGGATGGCAAGTAATCCGTGTTGAGGATGGA AACGATATTGAAGCTATCGCGAAAGCAATCGAAGAAGCGAAAGCTGACGAAAAACGCCCA ACGCTAATTGAAGTAAGAACGACAATTGGTTTCGGTTCTCCAAACAAATCAGGAAAATCA GCTTCACATGGTTCTCCACTTGGTGTAGAAGAAACAAAGTTAACGAAAGAAGCATACGCT TGGACTGCTGAACAAGACTTCCATGTAGCAGAAGAAGTATATGAAAACTTCCGTAAAACA GTACAAGATGTTGGTGAAACTGCACAAGCTGAGTGGAATACTATGCTAGGTGAATATGCA CAAGCATATCCAGAATTAGCAAACGAACTGCAAGCAGCAATGAACGGTCTTCTTCCAGAA GGTTGGGAGCAAAACTTACCAACTTATGAATTAGGATCAAAAGCAGCAACTCGTAATTCT TCAGGTGCTGTAATTAATGCAATTGCAGAGTCTGTACCATCATTCTTCGGTGGATCTGCT GACCTTGCTGGTTCTAACAAAACATACATGAATAACGAAAAAGACTTTACAAGAGATGAT TACAGCGGTAAAAACATTTGGTACGGTGTACGTGAGTTCGCAATGGGTGCAGCAATGAAC GGTATTGCACTACATGGTGGTTTAAAAACTTACGGTGGTACGTTCTTCGTATTCTCTGAC TACTTACGCCCAGCAATTCGTCTTGCAGCATTAATGCAATTGCCGGTAACGTATGTATTC ACACACGACAGTATCGCTGTTGGTGAAGATGGTCCAACACATGAACCAATCGAGCAATTA GCAGCGCTACGTGCAATGCCAAATGTATCTGTTATTCGTCCAGCTGACGGTAACGAATCT GTTGCAGCTTGGAGACTAGCTCTAGAATCTACAAACAAACCAACTGCTTTAGTATTAACT CGTCAAGATCTTCCAACATTAGAAGGTGCAAAAGACGATACGTATGAAAAAGTAGCAAAA GGTGCGTATGTAGTTTCTGCAAGCAAGAAAGAAACAGCTGATGTAATCTTACTTGCAACT GGATCTGAAGTAAGTCTAGCTGTTGAAGCTCAAAAAGCATTAGCAGTAGACGGCGTTGAT GCATCTGTTGTCAGCATGCCATCTATGGATCGCTTTGAAGCTCAAACAGCTGAGTACAAA GAATCTGTATTACCAAAAGCAGTAACAAAACGTTTCGCAATCGAAATGGGTGCTACATTC GGATGGCACCGTTACGTAGGTCTTGAAGGAGATGTGTTAGGTATCGATACATTCGGTGCT TCTGCTCCTGGTGAGAAGATTATGGAAGAGTATGGATTTACTGTAGAGAACGTTGTTCGT AAAGTAAAAGAAATGCTTTAA
- Chromosome Location
- Not Available
- Locus
- Not Available
- External Identifiers
Resource Link UniProtKB ID A0A6L7H165 UniProtKB Entry Name Q81Y15_BACAN GenBank Protein ID 30253517 GenBank Gene ID AE016879 PDB ID(s) 3HYL, 3M49 KEGG ID bar:GBAA_3744 - General References
- Ravel J, Jiang L, Stanley ST, Wilson MR, Decker RS, Read TD, Worsham P, Keim PS, Salzberg SL, Fraser-Liggett CM, Rasko DA: The complete genome sequence of Bacillus anthracis Ames "Ancestor". J Bacteriol. 2009 Jan;191(1):445-6. doi: 10.1128/JB.01347-08. Epub 2008 Oct 24. [Article]
Associated Data
- Bio-Entities
Bio-Entity Type Transketolase (Bacillus anthracis) protein primary- Drug Relations
Drug Drug group Pharmacological action? Type Actions Details Triglyme experimental unknown target Details