Actin-related protein 2/3 complex subunit 1B
Details
- Name
- Actin-related protein 2/3 complex subunit 1B
- Synonyms
- ARC41
- Arp2/3 complex 41 kDa subunit
- p41-ARC
- Gene Name
- ARPC1B
- Organism
- Humans
- Amino acid sequence
>lcl|BSEQ0017382|Actin-related protein 2/3 complex subunit 1B MAYHSFLVEPISCHAWNKDRTQIAICPNNHEVHIYEKSGAKWTKVHELKEHNGQVTGIDW APESNRIVTCGTDRNAYVWTLKGRTWKPTLVILRINRAARCVRWAPNENKFAVGSGSRVI SICYFEQENDWWVCKHIKKPIRSTVLSLDWHPNNVLLAAGSCDFKCRIFSAYIKEVEERP APTPWGSKMPFGELMFESSSSCGWVHGVCFSASGSRVAWVSHDSTVCLADADKKMAVATL ASETLPLLALTFITDNSLVAAGHDCFPVLFTYDAAAGMLSFGGRLDVPKQSSQRGLTARE RFQNLDKKASSEGGTAAGAGLDSLHKNSVSQISVLSGGKAKCSQFCTTGMDGGMSIWDVK SLESALKDLKIK
- Number of residues
- 372
- Molecular Weight
- 40949.415
- Theoretical pI
- 8.44
- GO Classification
- Functionsstructural constituent of cytoskeletonProcessesArp2/3 complex-mediated actin nucleation / axon guidance / ephrin receptor signaling pathway / Fc-gamma receptor signaling pathway involved in phagocytosis / innate immune response / movement of cell or subcellular component / small GTPase mediated signal transductionComponentsactin cytoskeleton / Arp2/3 protein complex / cytosol / extracellular exosome / focal adhesion
- General Function
- Structural constituent of cytoskeleton
- Specific Function
- Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks.
- Pfam Domain Function
- WD40 (PF00400)
- Transmembrane Regions
- Not Available
- Cellular Location
- Cytoplasm
- Gene sequence
>lcl|BSEQ0017383|Actin-related protein 2/3 complex subunit 1B (ARPC1B) ATGGCCTACCACAGCTTCCTGGTGGAGCCCATCAGCTGCCACGCCTGGAACAAGGACCGC ACCCAGATTGCCATCTGCCCCAACAACCATGAGGTGCATATCTATGAAAAGAGCGGTGCC AAATGGACCAAGGTGCACGAGCTCAAGGAGCACAACGGGCAGGTGACAGGCATCGACTGG GCCCCCGAGAGTAACCGTATTGTGACCTGCGGCACAGACCGCAACGCCTACGTGTGGACG CTGAAGGGCCGCACATGGAAGCCCACGCTGGTCATCCTGCGGATCAACCGGGCTGCCCGC TGCGTGCGCTGGGCCCCCAACGAGAACAAGTTTGCTGTGGGCAGCGGCTCTCGTGTGATC TCCATCTGTTATTTCGAGCAGGAGAATGACTGGTGGGTTTGCAAGCACATCAAGAAGCCC ATCCGCTCCACCGTCCTCAGCCTGGACTGGCACCCCAACAATGTGCTGCTGGCTGCCGGC TCCTGTGACTTCAAGTGTCGGATCTTTTCAGCCTACATCAAGGAGGTGGAGGAACGGCCG GCACCCACCCCGTGGGGCTCCAAGATGCCCTTTGGGGAACTGATGTTCGAATCCAGCAGT AGCTGCGGCTGGGTACATGGCGTCTGTTTCTCAGCCAGCGGGAGCCGCGTGGCCTGGGTA AGCCACGACAGCACCGTCTGCCTGGCTGATGCCGACAAGAAGATGGCCGTCGCGACTCTG GCCTCTGAAACACTACCACTGCTGGCGCTGACCTTCATCACAGACAACAGCCTGGTGGCA GCGGGCCACGACTGCTTCCCGGTGCTGTTCACCTATGACGCCGCCGCGGGGATGCTGAGC TTCGGCGGGCGGCTGGACGTTCCTAAGCAGAGCTCGCAGCGTGGCTTGACGGCCCGCGAG CGCTTCCAGAACCTGGACAAGAAGGCGAGCTCCGAGGGTGGCACGGCTGCGGGCGCGGGC CTAGACTCGCTGCACAAGAACAGCGTCAGCCAGATCTCGGTGCTCAGCGGCGGCAAGGCC AAGTGCTCGCAGTTCTGCACCACTGGCATGGATGGCGGCATGAGTATCTGGGATGTGAAG AGCTTGGAGTCAGCCTTGAAGGACCTCAAGATCAAATGA
- Chromosome Location
- 7
- Locus
- 7q22.1
- External Identifiers
Resource Link UniProtKB ID O15143 UniProtKB Entry Name ARC1B_HUMAN GenBank Protein ID 2282034 GenBank Gene ID AF006084 HGNC ID HGNC:704 - General References
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