P2X purinoceptor 6
Details
- Name
- P2X purinoceptor 6
- Synonyms
- ATP receptor
- P2RXL1
- P2X6
- P2XM
- Purinergic receptor
- Purinergic receptor P2X-like 1
- Gene Name
- P2RX6
- Organism
- Humans
- Amino acid sequence
>lcl|BSEQ0052209|P2X purinoceptor 6 MCPQLAGAGSMGSPGATTGWGLLDYKTEKYVMTRNWRVGALQRLLQFGIVVYVVGWALLA KKGYQERDLEPQFSIITKLKGVSVTQIKELGNRLWDVADFVKPPQGENVFFLVTNFLVTP AQVQGRCPEHPSVPLANCWVDEDCPEGEGGTHSHGVKTGQCVVFNGTHRTCEIWSWCPVE SGVVPSRPLLAQAQNFTLFIKNTVTFSKFNFSKSNALETWDPTYFKHCRYEPQFSPYCPV FRIGDLVAKAGGTFEDLALLGGSVGIRVHWDCDLDTGDSGCWPHYSFQLQEKSYNFRTAT HWWEQPGVEARTLLKLYGIRFDILVTGQAGKFGLIPTAVTLGTGAAWLGVVTFFCDLLLL YVDREAHFYWRTKYEEAKAPKATANSVWRELALASQARLAECLRRSSAPAPTATAAGSQT QTPGWPCPSSDTHLPTHSGSL
- Number of residues
- 441
- Molecular Weight
- 48828.32
- Theoretical pI
- Not Available
- GO Classification
- FunctionsATP binding / channel activity / extracellularly ATP-gated cation channel activity / purinergic nucleotide receptor activity / transmembrane signaling receptor activityProcessesblood coagulation / muscle contraction / protein heterooligomerization / response to ATP / signal transductionComponentscell junction / cytoplasm / dendritic spine / glutamatergic synapse / integral component of nuclear inner membrane / integral component of plasma membrane / integral component of postsynaptic specialization membrane / neuronal cell body / parallel fiber to Purkinje cell synapse / plasma membrane / postsynaptic density / receptor complex
- General Function
- Receptor for ATP that acts as a ligand-gated ion channel.
- Specific Function
- Atp binding
- Pfam Domain Function
- Not Available
- Transmembrane Regions
- 40-60 334-354
- Cellular Location
- Membrane
- Gene sequence
>lcl|BSEQ0052210|P2X purinoceptor 6 (P2RX6) ATGTGCCCGCAGCTAGCAGGAGCTGGCAGCATGGGCTCCCCAGGGGCTACGACAGGCTGG GGGCTTCTGGATTATAAGACGGAGAAGTATGTGATGACCAGGAACTGGCGGGTGGGCGCC CTGCAGAGGCTGCTGCAGTTTGGGATCGTGGTCTATGTGGTAGGGTGGGCTCTCCTCGCC AAAAAAGGCTACCAGGAGCGGGACCTGGAACCCCAGTTTTCCATCATCACCAAACTCAAA GGGGTTTCCGTCACTCAGATCAAGGAGCTTGGAAACCGGCTGTGGGATGTGGCCGACTTC GTGAAGCCACCTCAGGGAGAGAACGTGTTCTTCTTGGTGACCAACTTCCTTGTGACGCCA GCCCAAGTTCAGGGCAGATGCCCAGAGCACCCGTCCGTCCCACTGGCTAACTGCTGGGTC GACGAGGACTGCCCCGAAGGGGAGGGAGGCACACACAGCCACGGTGTAAAAACAGGCCAG TGTGTGGTGTTCAATGGGACCCACAGGACCTGTGAGATCTGGAGTTGGTGCCCCGTGGAG AGTGGCGTTGTGCCCTCGAGGCCCCTGCTGGCCCAGGCCCAGAACTTCACACTGTTCATC AAAAACACAGTCACCTTCAGCAAGTTCAACTTCTCTAAGTCCAATGCCTTGGAGACCTGG GACCCCACCTATTTTAAGCACTGCCGCTATGAACCACAATTCAGCCCCTACTGTCCCGTG TTCCGCATTGGGGACCTCGTGGCCAAGGCTGGAGGGACCTTCGAGGACCTGGCGTTGCTG GGTGGCTCTGTAGGCATCAGAGTTCACTGGGATTGTGACCTGGACACCGGGGACTCTGGC TGCTGGCCTCACTACTCCTTCCAGCTGCAGGAGAAGAGCTACAACTTCAGGACAGCCACT CACTGGTGGGAGCAACCGGGTGTGGAGGCCCGCACCCTGCTCAAGCTCTATGGAATCCGC TTCGACATCCTCGTCACCGGGCAGGCAGGGAAGTTCGGGCTCATCCCCACGGCCGTCACA CTGGGCACCGGGGCAGCTTGGCTGGGCGTGGTCACCTTTTTCTGTGACCTGCTACTGCTG TATGTGGATAGAGAAGCCCATTTCTACTGGAGGACAAAGTATGAGGAGGCCAAGGCCCCG AAAGCAACCGCCAACTCTGTGTGGAGGGAGCTGGCCCTTGCATCCCAAGCCCGACTGGCC GAGTGCCTCAGACGGAGCTCAGCACCTGCACCCACGGCCACTGCTGCTGGGAGTCAGACA CAGACACCAGGATGGCCCTGTCCAAGTTCTGACACCCACTTGCCAACCCATTCCGGGAGC CTGTAG
- Chromosome Location
- 22
- Locus
- 22q11.21
- External Identifiers
Resource Link UniProtKB ID O15547 UniProtKB Entry Name P2RX6_HUMAN HGNC ID HGNC:8538 - General References
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