PCZA361.16
Details
- Name
- PCZA361.16
- Synonyms
- Not Available
- Gene Name
- Not Available
- Organism
- Amycolatopsis orientalis
- Amino acid sequence
>lcl|BSEQ0016808|PCZA361.16 MQARKLAVDGAIEFTPRVFADDRGLLILPYQEEAFVEAHGGPLFRVAQTIHSMSKRGVVR GIHYTVTPPGTAKYVYCARGKAMDIVIDIRVGSPTFGQWDSVLMDQQDPRAVYLPVGVGH AFVALEDDTVMSYMLSRSYVTQDELALSALDPALGLPIDIGVEPIVSDRDRVAITLAEAQ RQGLLPDYTTSQEIERRLTAVPVST
- Number of residues
- 205
- Molecular Weight
- 22488.53
- Theoretical pI
- 4.86
- GO Classification
- FunctionsdTDP-4-dehydrorhamnose 3,5-epimerase activity
- General Function
- Dtdp-4-dehydrorhamnose 3,5-epimerase activity
- Specific Function
- Not Available
- Pfam Domain Function
- dTDP_sugar_isom (PF00908)
- Transmembrane Regions
- Not Available
- Cellular Location
- Not Available
- Gene sequence
>lcl|BSEQ0004891|618 bp GTGCAAGCACGCAAACTCGCCGTCGACGGCGCGATCGAGTTCACCCCTCGCGTCTTCGCC GACGACCGGGGCCTGTTGATCCTGCCGTACCAGGAAGAGGCCTTCGTCGAGGCGCACGGC GGCCCGCTTTTCCGTGTGGCACAGACGATCCACAGCATGTCCAAGCGCGGCGTGGTGCGG GGCATCCACTACACCGTGACGCCACCGGGTACCGCCAAATACGTCTACTGCGCCCGCGGC AAGGCCATGGACATCGTGATCGACATCAGAGTCGGCTCGCCCACGTTCGGGCAGTGGGAC TCGGTGCTGATGGACCAGCAGGATCCCCGGGCGGTGTACCTTCCGGTCGGCGTCGGCCAT GCGTTCGTGGCCCTCGAGGACGACACCGTCATGTCGTACATGCTCTCCAGAAGCTATGTG ACGCAGGACGAACTCGCCCTCTCGGCCCTGGATCCCGCACTGGGCCTGCCCATCGACATC GGCGTCGAACCGATCGTGTCCGATCGGGACCGGGTGGCCATCACGCTCGCCGAGGCCCAG CGGCAGGGCCTGCTGCCGGATTACACCACCAGTCAGGAGATCGAGCGGCGGCTGACCGCG GTCCCCGTCTCGACCTGA
- Chromosome Location
- Not Available
- Locus
- Not Available
- External Identifiers
Resource Link UniProtKB ID O52806 UniProtKB Entry Name O52806_AMYOR GenBank Gene ID AJ223998 - General References
- van Wageningen AM, Kirkpatrick PN, Williams DH, Harris BR, Kershaw JK, Lennard NJ, Jones M, Jones SJ, Solenberg PJ: Sequencing and analysis of genes involved in the biosynthesis of a vancomycin group antibiotic. Chem Biol. 1998 Mar;5(3):155-62. [Article]
- Merkel AB, Temple GK, Burkart MD, Losey HC, Beis K, Walsh CT, Naismith JH: Purification, crystallization and preliminary structural studies of dTDP-4-keto-6-deoxy-glucose-5-epimerase (EvaD) from Amycolatopsis orientalis, the fourth enzyme in the dTDP-L-epivancosamine biosynthetic pathway. Acta Crystallogr D Biol Crystallogr. 2002 Jul;58(Pt 7):1226-8. Epub 2002 Jun 20. [Article]
- Merkel AB, Major LL, Errey JC, Burkart MD, Field RA, Walsh CT, Naismith JH: The position of a key tyrosine in dTDP-4-Keto-6-deoxy-D-glucose-5-epimerase (EvaD) alters the substrate profile for this RmlC-like enzyme. J Biol Chem. 2004 Jul 30;279(31):32684-91. Epub 2004 May 24. [Article]