Phenazine biosynthesis protein

Details

Name

Phenazine biosynthesis protein

Synonyms

• Phenazine biosynthesis protein phzD
• Phenazine biosynthesis protein PhzG
• phzD
• PhzG
• phzG1
• phzG1_1
• phzG1_2
• Putative pyridoxamine 5'-phosphate oxidase
• Pyridoxamine 5'-phosphate oxidase

Gene Name

phzG

Organism

Pseudomonas aeruginosa

Amino acid sequence

>lcl|BSEQ0022501|Phenazine biosynthesis protein
MGVNANISESLTGTIEAPFPEFEAPPANPMEVLRNWLERARRYGVREPRALALATVDGQG
RPSTRIVVIAELGERGVVFATHADSQKGRELAQNPWASGVLYWRESSQQIILNGRAERLP
DERADAQWLSRPYQTHPMSIASRQSETLADIHALRAEARRLAETDGPLPRPPGYCLFELC
LESVEFWGNGTERLHERLRYDRDEGGWKHRYLQP

Number of residues

214

Molecular Weight

24268.005

Theoretical pI

6.37

GO Classification

Functions

FMN binding / pyridoxamine-phosphate oxidase activity

Processes

phenazine biosynthetic process / pyridoxine biosynthetic process

General Function

Pyridoxamine-phosphate oxidase activity

Specific Function

Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).

Pfam Domain Function

• Pyridox_oxidase (PF01243)
• PNPOx_C (PF10590)

Transmembrane Regions

Not Available

Cellular Location

Not Available

Gene sequence

>lcl|BSEQ0022502|Phenazine biosynthesis protein (phzG)
ATGGGCGTCAACGCGAACATTTCCGAGTCCCTCACCGGGACCATCGAAGCCCCTTTCCCG
GAGTTCGAGGCGCCGCCGGCGAACCCCATGGAGGTGCTGCGCAACTGGCTGGAACGCGCC
CGCCGCTACGGCGTGCGCGAGCCGCGGGCACTGGCCCTGGCCACGGTCGACGGGCAGGGC
CGGCCGTCGACGCGGATCGTGGTGATCGCCGAGCTGGGCGAGCGCGGGGTGGTGTTCGCC
ACCCACGCCGATAGCCAGAAGGGCCGCGAACTGGCGCAGAACCCCTGGGCCTCGGGGGTG
CTGTACTGGCGCGAGAGCAGCCAGCAGATCATCCTCAACGGCCGCGCCGAACGCCTGCCC
GACGAGCGCGCCGACGCCCAGTGGCTGAGCCGCCCGTACCAGACCCACCCGATGTCGATC
GCCTCGCGGCAGAGCGAAACCCTCGCCGACATCCACGCCCTGCGCGCCGAAGCCCGGCGC
CTGGCGGAAACCGACGGCCCGCTGCCGCGCCCGCCGGGCTACTGCCTGTTCGAACTGTGC
CTGGAGTCGGTGGAGTTCTGGGGCAACGGCACCGAGCGGCTGCACGAGCGCCTGCGCTAC
GACCGCGACGAAGGAGGCTGGAAGCACCGCTACCTGCAACCGTGA

Chromosome Location

Not Available

Locus

Not Available

External Identifiers

Resource	Link
UniProtKB ID	O69755
UniProtKB Entry Name	O69755_PSEAI
GenBank Gene ID	AF005404

General References

1. Parsons JF, Calabrese K, Eisenstein E, Ladner JE: Structure of the phenazine biosynthesis enzyme PhzG. Acta Crystallogr D Biol Crystallogr. 2004 Nov;60(Pt 11):2110-3. Epub 2004 Oct 20. [Article]

Drug Relations

Drug Relations

DrugBank ID	Name	Drug group	Pharmacological action?	Actions	Details
DB03247	Flavin mononucleotide	approved, investigational	unknown		Details