Porin P
Details
- Name
- Porin P
- Synonyms
- Outer membrane protein D1
- Gene Name
- oprP
- Organism
- Pseudomonas aeruginosa (strain ATCC 15692 / PAO1 / 1C / PRS 101 / LMG 12228)
- Amino acid sequence
>lcl|BSEQ0012764|Porin P MIRRHSCKGVGSSVAWSLLGLAISAQSLAGTVTTDGADIVIKTKGGLEVATTDKEFSFKL GGRLQADYGRFDGYYTNNGNTADAAYFRRAYLEFGGTAYRDWKYQINYDLSRNVGNDSAG YFDEASVTYTGFNPVNLKFGRFYTDFGLEKATSSKWVTALERNLTYDIADWVNDNVGTGI QASSVVGGMAFLSGSVFSENNNDTDGDSVKRYNLRGVFAPLHEPGNVVHLGLQYAYRDLE DSAVDTRIRPRMGMRGVSTNGGNDAGSNGNRGLFGGSSAVEGLWKDDSVWGLEGAWALGA FSAQAEYLRRTVKAERDREDLKASGYYAQLAYTLTGEPRLYKLDGAKFDTIKPENKEIGA WELFYRYDSIKVEDDNIVVDSATREVGDAKGKTHTLGVNWYANEAVKVSANYVKAKTDKI SNANGDDSGDGLVMRLQYVF
- Number of residues
- 440
- Molecular Weight
- 48210.955
- Theoretical pI
- 5.21
- GO Classification
- Functionsporin activityProcessesion transportComponentscell outer membrane / pore complex
- General Function
- Porin activity
- Specific Function
- Anion specific, the binding site has higher affinity for phosphate than chloride ions. Porin O has a higher affinity for polyphosphates (tripolyphosphate and pyrophosphate) while porin P has a higher affinity for orthophosphate.
- Pfam Domain Function
- Porin_O_P (PF07396)
- Transmembrane Regions
- Not Available
- Cellular Location
- Cell outer membrane
- Gene sequence
>lcl|BSEQ0012765|Porin P (oprP) ATGATTCGCAGACACTCGTGCAAAGGGGTGGGGAGCAGTGTTGCCTGGAGTTTGCTGGGC CTGGCGATTTCCGCGCAGAGCCTGGCCGGGACCGTGACCACCGACGGTGCCGACATCGTG ATCAAGACCAAGGGCGGCCTCGAAGTCGCCACCACCGACAAGGAATTCAGCTTCAAGCTC GGCGGCCGCCTGCAGGCCGACTACGGCCGCTTCGACGGCTACTACACGAACAACGGCAAT ACCGCCGATGCCGCCTACTTCCGCCGCGCCTACCTGGAGTTCGGCGGCACCGCCTACCGG GACTGGAAGTACCAGATCAACTACGACCTGTCGCGCAACGTCGGCAACGACAGCGCCGGC TACTTTGACGAAGCTTCGGTCACCTATACCGGCTTCAACCCGGTCAACCTGAAGTTCGGC CGCTTCTACACCGACTTCGGCCTGGAAAAGGCCACCAGCTCCAAATGGGTCACCGCGCTG GAGCGCAACCTCACCTACGACATCGCCGACTGGGTCAACGACAACGTCGGTACCGGTATC CAAGCCAGCTCGGTGGTGGGCGGCATGGCTTTCCTCTCTGGCAGCGTGTTCAGCGAGAAC AACAACGATACCGACGGCGACAGCGTCAAGCGCTACAACCTGCGCGGCGTGTTCGCGCCG CTGCACGAGCCGGGCAACGTGGTGCACCTGGGCCTGCAATACGCCTATCGCGACCTGGAG GACAGCGCGGTGGATACCCGGATCCGCCCGCGCATGGGCATGCGCGGCGTCTCCACCAAT GGCGGCAACGATGCCGGCAGCAATGGCAACCGCGGTCTGTTCGGCGGCAGTTCGGCAGTC GAGGGGCTGTGGAAGGACGACTCGGTCTGGGGCCTGGAAGGCGCCTGGGCGCTGGGTGCC TTCTCGGCCCAGGCCGAGTACCTGCGGCGCACGGTCAAGGCCGAGCGCGACCGCGAGGAT CTCAAGGCCTCCGGCTATTACGCGCAACTGGCCTACACCCTCACCGGCGAGCCGCGCCTC TACAAGCTGGACGGCGCCAAGTTCGACACCATCAAGCCGGAGAACAAGGAAATCGGCGCC TGGGAGCTGTTCTACCGCTACGACTCGATCAAGGTCGAGGATGACAACATCGTCGTCGAC AGCGCCACCCGCGAGGTCGGCGACGCCAAGGGCAAGACCCATACCCTGGGCGTCAACTGG TACGCCAACGAGGCGGTGAAGGTTTCCGCCAACTACGTCAAGGCGAAGACCGACAAGATC AGCAATGCCAACGGCGACGATAGCGGCGATGGCCTGGTGATGCGCCTGCAGTACGTGTTC TGA
- Chromosome Location
- Not Available
- Locus
- Not Available
- External Identifiers
Resource Link UniProtKB ID P05695 UniProtKB Entry Name PORP_PSEAE GenBank Protein ID 45379 GenBank Gene ID X53313 - General References
- Siehnel R, Martin NL, Hancock RE: Sequence and relatedness in other bacteria of the Pseudomonas aeruginosa oprP gene coding for the phosphate-specific porin P. Mol Microbiol. 1990 May;4(5):831-8. [Article]
- Siehnel RJ, Egli C, Hancock RE: Polyphosphate-selective porin OprO of Pseudomonas aeruginosa: expression, purification and sequence. Mol Microbiol. 1992 Aug;6(16):2319-26. [Article]
- Stover CK, Pham XQ, Erwin AL, Mizoguchi SD, Warrener P, Hickey MJ, Brinkman FS, Hufnagle WO, Kowalik DJ, Lagrou M, Garber RL, Goltry L, Tolentino E, Westbrock-Wadman S, Yuan Y, Brody LL, Coulter SN, Folger KR, Kas A, Larbig K, Lim R, Smith K, Spencer D, Wong GK, Wu Z, Paulsen IT, Reizer J, Saier MH, Hancock RE, Lory S, Olson MV: Complete genome sequence of Pseudomonas aeruginosa PAO1, an opportunistic pathogen. Nature. 2000 Aug 31;406(6799):959-64. [Article]
- Siehnel RJ, Worobec EA, Hancock RE: Regulation of components of the Pseudomonas aeruginosa phosphate-starvation-inducible regulon in Escherichia coli. Mol Microbiol. 1988 May;2(3):347-52. [Article]
- Worobec EA, Martin NL, McCubbin WD, Kay CM, Brayer GD, Hancock RE: Large-scale purification and biochemical characterization of crystallization-grade porin protein P from Pseudomonas aeruginosa. Biochim Biophys Acta. 1988 Apr 7;939(2):366-74. [Article]
- Hancock RE, Benz R: Demonstration and chemical modification of a specific phosphate binding site in the phosphate-starvation-inducible outer membrane porin protein P of Pseudomonas aeruginosa. Biochim Biophys Acta. 1986 Sep 11;860(3):699-707. [Article]