Small ribosomal subunit protein eS17

Details

Name
Small ribosomal subunit protein eS17
Synonyms
  • 40S ribosomal protein S17
  • RPS17L
Gene Name
RPS17
UniProtKB Entry
P08708Swiss-Prot
Organism
Humans
NCBI Taxonomy ID
9606
Amino acid sequence
>lcl|BSEQ0049928|Small ribosomal subunit protein eS17
MGRVRTKTVKKAARVIIEKYYTRLGNDFHTNKRVCEEIAIIPSKKLRNKIAGYVTHLMKR
IQRGPVRGISIKLQEEERERRDNYVPEVSALDQEIIEVDPDTKEMLKLLDFGSLSNLQVT
QPTVGMNFKTPRGPV
Number of residues
135
Molecular Weight
15550.02
Theoretical pI
Not Available
GO Classification
Processes
cytoplasmic translation
Components
cytoplasm / cytosolic ribosome / nucleolus / small-subunit processome / synapse
General Function
Component of the small ribosomal subunit (PubMed:23636399). The ribosome is a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell (PubMed:23636399). Part of the small subunit (SSU) processome, first precursor of the small eukaryotic ribosomal subunit. During the assembly of the SSU processome in the nucleolus, many ribosome biogenesis factors, an RNA chaperone and ribosomal proteins associate with the nascent pre-rRNA and work in concert to generate RNA folding, modifications, rearrangements and cleavage as well as targeted degradation of pre-ribosomal RNA by the RNA exosome (PubMed:34516797)
Specific Function
Rna binding
Pfam Domain Function
Signal Regions
Not Available
Transmembrane Regions
Not Available
Cellular Location
Cytoplasm
Gene sequence
>lcl|BSEQ0049929|40S ribosomal protein S17 (RPS17)
ATGGGCCGCGTTCGCACCAAAACCGTGAAGAAGGCGGCCCGGGTCATCATAGAAAAGTAC
TACACGCGCCTGGGCAACGACTTCCACACGAACAAGCGCGTGTGCGAGGAGATCGCCATT
ATCCCCAGCAAAAAGCTCCGCAACAAGATAGCAGGTTATGTCACGCATCTGATGAAGCGA
ATTCAGAGAGGCCCAGTAAGAGGTATCTCCATCAAGCTGCAGGAGGAGGAGAGAGAAAGG
AGAGACAATTATGTTCCTGAGGTCTCAGCCTTGGATCAGGAGATTATTGAAGTAGATCCT
GACACTAAGGAAATGCTGAAGCTTTTGGACTTCGGCAGTCTGTCCAACCTTCAGGTCACT
CAGCCTACAGTTGGGATGAATTTCAAAACGCCTCGGGGACCTGTTTGA
Chromosome Location
15
Locus
15q25.2
External Identifiers
ResourceLink
UniProtKB IDP08708
UniProtKB Entry NameRS17_HUMAN
GeneCard IDRPS17
HGNC IDHGNC:10397
PDB ID(s)4UG0, 4V6X, 5A2Q, 5AJ0, 5FLX, 5LKS, 5OA3, 5T2C, 5VYC, 6FEC, 6G18, 6G4S, 6G4W, 6G51, 6G53, 6G5H, 6G5I, 6IP5, 6IP6, 6IP8, 6OLE, 6OLF, 6OLG, 6OLI, 6OLZ, 6OM0, 6OM7, 6QZP, 6XA1, 6Y0G, 6Y2L, 6Y57, 6YBD, 6YBS, 6YBW, 6Z6L, 6Z6M, 6Z6N, 6ZLW, 6ZM7, 6ZME, 6ZMI, 6ZMO, 6ZMT, 6ZMW, 6ZN5, 6ZOJ, 6ZOK, 6ZOL, 6ZON, 6ZP4, 6ZUO, 6ZV6, 6ZVH, 6ZVJ, 6ZXD, 6ZXE, 6ZXF, 6ZXG, 6ZXH, 7A09, 7K5I, 7MQ8, 7MQ9, 7MQA, 7QP6, 7QP7, 7QVP, 7R4X, 7TQL, 7WTT, 7WTU, 7WTV, 7WTW, 7WTX, 7WTZ, 7WU0, 7XNX, 7XNY, 8G5Y, 8G5Z, 8G60, 8G61, 8G6J, 8GLP, 8IFD, 8IFE, 8JDJ, 8JDK, 8JDL, 8JDM, 8OZ0, 8PPK, 8PPL, 8T4S, 8Y0W, 8Y0X
KEGG IDhsa:6218
NCBI Gene ID6218
General References
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Associated Data

Bio-Entities
Bio-EntityType
Small ribosomal subunit protein eS17 (Humans)protein
primary
Drug Relations
DrugDrug groupPharmacological action?TypeActionsDetails
Artenimolapproved, experimental, investigationalunknowntargetligandDetails