NAD(P) transhydrogenase subunit beta
Details
- Name
- NAD(P) transhydrogenase subunit beta
- Synonyms
- 1.6.1.2
- dIII
- Nicotinamide nucleotide transhydrogenase subunit beta
- nntB
- Proton-translocating transhydrogenase NADP(H)-binding component
- Pyridine nucleotide transhydrogenase subunit beta
- Gene Name
- pntB
- Organism
- Rhodospirillum rubrum
- Amino acid sequence
>lcl|BSEQ0011501|NAD(P) transhydrogenase subunit beta MTHSLTMAAYIVAGVLFILALRGLSNPESARNGNRMGMVGMAIAILTTLLSPSVQAYAWI VLAIAIGGAIGTVIAKKVLMTALPQLVAAFHSLVGMAAVLVATGALLNPEAYGIGSAGAI HAGSLVEMSLGLAVGAITFSGSVIAFGKLQGLIAGKPVTFPMQHPLNAVLGILLVVLLVV FAATESHTAYFALMILAFALGFLLIIPIGGADMPVVISMLNSYSGWAAAGIGFTLGNPLL IIAGALVGSSGAILSYIMCKGMNRSIFNVILGGFGSEGGVAAAGGAAGDRSVKAGSAEDA AFIMKNASKVIIVPGYGMAVAQAQHALREMADVLKKEGVEVSYAIHPVAGRMPGHMNVLL AEANVPYDEVFELEEINSSFQTADVAFVIGANDVTNPAAKTDPSSPIYGMPILDVEKAGT VLFIKRSMASGYAGVENELFFRNNTMMLFGDAKKMTEQIVQAMN
- Number of residues
- 464
- Molecular Weight
- 47807.835
- Theoretical pI
- 6.52
- GO Classification
- FunctionsNAD(P)+ transhydrogenase (AB-specific) activity / NADP bindingProcessesoxidation-reduction processComponentsintegral component of membrane / plasma membrane
- General Function
- Nadp binding
- Specific Function
- The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane.
- Pfam Domain Function
- PNTB (PF02233)
- Transmembrane Regions
- 54-74 86-106 126-146 164-184 191-211 227-247
- Cellular Location
- Cell inner membrane
- Chromosome Location
- Not Available
- Locus
- Not Available
- External Identifiers
Resource Link UniProtKB ID P0C188 UniProtKB Entry Name PNTB_RHORU GenBank Gene ID U01158 - General References
- Yamaguchi M, Hatefi Y: Energy-transducing nicotinamide nucleotide transhydrogenase: nucleotide sequences of the genes and predicted amino acid sequences of the subunits of the enzyme from Rhodospirillum rubrum. J Bioenerg Biomembr. 1994 Aug;26(4):435-45. [Article]
- Jeeves M, Smith KJ, Quirk PG, Cotton NP, Jackson JB: Solution structure of the NADP(H)-binding component (dIII) of proton-translocating transhydrogenase from Rhodospirillum rubrum. Biochim Biophys Acta. 2000 Aug 15;1459(2-3):248-57. [Article]
- Cotton NP, White SA, Peake SJ, McSweeney S, Jackson JB: The crystal structure of an asymmetric complex of the two nucleotide binding components of proton-translocating transhydrogenase. Structure. 2001 Feb 7;9(2):165-76. [Article]