Myosin light chain 6B
Details
- Name
- Myosin light chain 6B
- Synonyms
- MLC1SA
- Myosin light chain 1 slow-twitch muscle A isoform
- Smooth muscle and nonmuscle myosin light chain alkali 6B
- Gene Name
- MYL6B
- Organism
- Humans
- Amino acid sequence
>lcl|BSEQ0017399|Myosin light chain 6B MPPKKDVPVKKPAGPSISKPAAKPAAAGAPPAKTKAEPAVPQAPQKTQEPPVDLSKVVIE FNKDQLEEFKEAFELFDRVGDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDELKSR RVDFETFLPMLQAVAKNRGQGTYEDYLEGFRVFDKEGNGKVMGAELRHVLTTLGEKMTEE EVETVLAGHEDSNGCINYEAFLKHILSV
- Number of residues
- 208
- Molecular Weight
- 22763.855
- Theoretical pI
- 5.44
- GO Classification
- Functionscalcium ion binding / motor activity / structural constituent of muscleProcessesmuscle contraction / muscle filament sliding / skeletal muscle tissue developmentComponentscytosol / extracellular exosome / muscle myosin complex / myosin complex / unconventional myosin complex
- General Function
- Structural constituent of muscle
- Specific Function
- Regulatory light chain of myosin. Does not bind calcium.
- Pfam Domain Function
- Not Available
- Transmembrane Regions
- Not Available
- Cellular Location
- Not Available
- Gene sequence
>lcl|BSEQ0017400|Myosin light chain 6B (MYL6B) ATGCCTCCCAAGAAGGATGTTCCCGTGAAGAAACCAGCAGGGCCCTCCATCTCCAAACCT GCTGCTAAGCCAGCAGCAGCAGGGGCTCCTCCAGCCAAGACCAAAGCTGAGCCAGCTGTC CCCCAGGCCCCTCAGAAAACCCAGGAGCCTCCAGTCGATCTCTCCAAAGTGGTGATCGAG TTTAACAAGGACCAGCTGGAGGAGTTCAAGGAGGCCTTCGAGCTGTTTGACCGAGTGGGG GATGGCAAGATCCTGTACAGCCAGTGTGGGGACGTGATGAGGGCCCTGGGCCAGAACCCC ACCAACGCCGAGGTGCTCAAGGTCCTGGGGAACCCCAAGAGTGATGAGCTGAAGTCGCGG CGTGTGGACTTTGAGACTTTCCTGCCCATGCTCCAGGCAGTGGCCAAGAACCGAGGCCAA GGCACATATGAGGACTACTTGGAGGGGTTTCGTGTGTTTGACAAGGAGGGGAACGGCAAA GTCATGGGAGCAGAGCTCAGACATGTTCTCACCACCCTTGGAGAGAAGATGACTGAGGAG GAGGTGGAGACCGTTCTGGCAGGACACGAGGACAGCAACGGCTGCATCAACTACGAGGCC TTCTTGAAACACATCCTAAGCGTCTGA
- Chromosome Location
- 12
- Locus
- 12q13.13
- External Identifiers
Resource Link UniProtKB ID P14649 UniProtKB Entry Name MYL6B_HUMAN GenBank Protein ID 34676 GenBank Gene ID X16434 HGNC ID HGNC:29823 - General References
- Hailstones DL, Gunning PW: Characterization of human myosin light chains 1sa and 3nm: implications for isoform evolution and function. Mol Cell Biol. 1990 Mar;10(3):1095-104. [Article]
- Zimmermann K, Starzinski-Powitz A: A novel isoform of myosin alkali light chain isolated from human muscle cells. Nucleic Acids Res. 1989 Dec 25;17(24):10496. [Article]
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- Burkard TR, Planyavsky M, Kaupe I, Breitwieser FP, Burckstummer T, Bennett KL, Superti-Furga G, Colinge J: Initial characterization of the human central proteome. BMC Syst Biol. 2011 Jan 26;5:17. doi: 10.1186/1752-0509-5-17. [Article]